iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090510

Ensembl Protein ID

ENSPTRP00000045907.3

UniProt Accession

H2R3Q8; H2R3Q8_PANTR

Genbank Protein ID

JAA10577.1; JAA21399.1; JAA43531.1

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AACZ03061604; GABF01000746; GABE01001208

Gene Name

WHSC1L1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000020173.5	ENSPTRT00000045036.3	ENSPTRP00000045907.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.30e-11	42.3	702	746

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCr 52
           +vC +C+++g+   sl+ Ce  C++ fH +Cl+l+   +lp+s+ +iC +C+
   Q: 702  TVCQICESSGD---SLIACEGeCCKHFHLECLGLT---SLPDSK-FICMECK 746
           79********9...5********************...*****7.******7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDFSFSFMQG IMGNTIQQPP QLIDSANIRQ EDAFDNNSDI AEDGGQTPYE ATLQQGFQYP 60
ATTEDLPQLT NGYPSSISVY ETQTKYQSYN QYPNGSANGF GAVRNFSPTD YYHSEIPNTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGCTTTG TGCGCGGCGG CGGCGGGAGA GGCGGCGGCG GCGGCCAGCA CGGAGGCGGA 60
GGCCGAGGGG GCTGTGCACA GGTCGCCGCG GAGAGGCGTG CGAATTCCGA GCCGAGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000310	Aegilops tauschii	29.41	4.00e-12	66.60
IUUC-Aml-001809	Ailuropoda melanoleuca	95.42	0.00e+00	1761.00
IUUC-Apl-004027	Anas platyrhynchos	78.37	0.00e+00	2101.00
IUUC-Aca-005380	Anolis carolinensis	82.88	0.00e+00	2237.00
IUUC-Ame-011234	Astyanax mexicanus	67.75	0.00e+00	1267.00
IUUC-Bta-013575	Bos taurus	92.43	0.00e+00	2642.00
IUUC-Bdi-014781	Brachypodium distachyon	34.76	3.00e-13	70.50
IUUC-Cja-020013	Callithrix jacchus	98.26	0.00e+00	2853.00
IUUC-Cfa-021060	Canis familiaris	96.11	0.00e+00	2686.00
IUUC-Cpo-021834	Cavia porcellus	94.58	0.00e+00	2608.00
IUUC-Csa-023370	Chlorocebus sabaeus	98.33	0.00e+00	2852.00
IUUC-Cho-025058	Choloepus hoffmanni	87.42	0.00e+00	1122.00
IUUC-Dre-027664	Danio rerio	61.74	0.00e+00	1512.00
IUUC-Dno-029302	Dasypus novemcinctus	94.03	0.00e+00	2628.00
IUUC-Eca-033626	Equus caballus	93.55	0.00e+00	2659.00
IUUC-Fca-035556	Felis catus	95.55	0.00e+00	2716.00
IUUC-Fal-037101	Ficedula albicollis	82.91	0.00e+00	2245.00
IUUC-Gmo-038901	Gadus morhua	57.77	0.00e+00	1574.00
IUUC-Gga-040366	Gallus gallus	83.71	0.00e+00	2221.00
IUUC-Gac-042047	Gasterosteus aculeatus	62.68	0.00e+00	1385.00
IUUC-Ggo-044695	Gorilla gorilla	96.26	0.00e+00	2736.00
IUUC-Hsa-046080	Homo sapiens	99.65	0.00e+00	2863.00
IUUC-Itr-048622	Ictidomys tridecemlineatus	95.69	0.00e+00	2730.00
IUUC-Lch-050544	Latimeria chalumnae	70.76	0.00e+00	1672.00
IUUC-Loc-052656	Lepisosteus oculatus	65.95	0.00e+00	1632.00
IUUC-Laf-054112	Loxodonta africana	95.01	0.00e+00	2680.00
IUUC-Mcc-054956	Macaca mulatta	98.96	0.00e+00	2865.00
IUUC-Meu-056051	Macropus eugenii	86.39	0.00e+00	2256.00
IUUC-Mga-060139	Meleagris gallopavo	85.92	0.00e+00	2299.00
IUUC-Mmr-060789	Microcebus murinus	96.04	0.00e+00	2788.00
IUUC-Mdo-062908	Monodelphis domestica	90.29	0.00e+00	2531.00
IUUC-Mmu-063165	Mus musculus	87.42	0.00e+00	2444.00
IUUC-Mpu-066002	Mustela putorius furo	96.11	0.00e+00	2712.00
IUUC-Nle-069417	Nomascus leucogenys	98.01	0.00e+00	2670.00
IUUC-Ont-071900	Oreochromis niloticus	59.58	0.00e+00	1662.00
IUUC-Oan-072857	Ornithorhynchus anatinus	90.56	0.00e+00	2546.00
IUUC-Ocu-073809	Oryctolagus cuniculus	95.35	0.00e+00	2679.00
IUUC-Obr-076122	Oryza brachyantha	30.36	5.00e-09	54.70
IUUC-Ola-087085	Oryzias latipes	59.43	0.00e+00	1627.00
IUUC-Oga-088289	Otolemur garnettii	94.99	0.00e+00	2677.00
IUUC-Oar-089398	Ovis aries	93.12	0.00e+00	2640.00
IUUC-Pan-092291	Papio anubis	98.47	0.00e+00	2857.00
IUUC-Psi-093547	Pelodiscus sinensis	87.52	0.00e+00	2382.00
IUUC-Pma-094747	Petromyzon marinus	48.72	0.00e+00	1098.00
IUUC-Pfo-096669	Poecilia formosa	60.00	0.00e+00	1629.00
IUUC-Pab-097727	Pongo abelii	98.68	0.00e+00	2838.00
IUUC-Pca-100474	Procavia capensis	87.04	0.00e+00	2343.00
IUUC-Pva-102539	Pteropus vampyrus	94.25	0.00e+00	2414.00
IUUC-Rno-105685	Rattus norvegicus	90.03	0.00e+00	2484.00
IUUC-Sha-107287	Sarcophilus harrisii	91.39	0.00e+00	2525.00
IUUC-Sar-113547	Sorex araneus	88.69	0.00e+00	2534.00
IUUC-Ssc-116208	Sus scrofa	96.18	0.00e+00	2781.00
IUUC-Tgu-117006	Taeniopygia guttata	85.57	0.00e+00	2341.00
IUUC-Tru-118375	Takifugu rubripes	59.23	0.00e+00	1660.00
IUUC-Tsy-119323	Tarsius syrichta	96.11	0.00e+00	2723.00
IUUC-Tni-120509	Tetraodon nigroviridis	59.75	0.00e+00	1672.00
IUUC-Tca-121456	Theobroma cacao	32.35	2.00e-19	91.30
IUUC-Tae-124687	Triticum aestivum	29.41	4.00e-12	66.60
IUUC-Ttr-128240	Tursiops truncatus	93.53	0.00e+00	2605.00
IUUC-Vpa-130666	Vicugna pacos	94.85	0.00e+00	2654.00
IUUC-Xma-134036	Xiphophorus maculatus	60.19	0.00e+00	1644.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence