iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093187

Ensembl Protein ID

ENSPSIP00000020372.1

UniProt Accession

K7GJB1; K7GJB1_PELSI

Genbank Protein ID

ENSPSIP00000020372

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01203173

Gene Name

USP8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000018031.1	ENSPSIT00000020468.1	ENSPSIP00000020372.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-33	116.0	747	857

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmNS+LQcL n p l++++++  ++e++n+ n  ++kge+++++  ++++lw+++ +++sp++++ +++k++ +fsgy+
   Q: 747  TGLRNLGNTCYMNSILQCLCNAPLLADYFNRnLYQEDINRLNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFSGYS 835
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkke 110
           qqD+qE+l fl+d+l+e+l+k 
   Q: 836  QQDSQELLLFLMDGLHEDLNKV 857
           *******************774 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MPAVASVPKE LYLCTSLKDL NKKTEIKAEK TSTKNYVQSA LKIFKAAEEC RLDRDEEKAY 60
VLYMKYVTVY DLIKKRPDFK QQQDYFLSIL GPTNIKKAIE EAERLSDSLK LRYEEAEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGTCGACC CCCACGCATC CAGACTATCG CGCTGAGCCG ACAAACAGCT GATCAGCTGT 60
TTGTCGGCTC AGGGTGGCAG CCATGTAAAT TTAAATGAAG CAGCGATTAT TTAAATCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS50235--USP_3

Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer

SMART

SM00450--RHOD

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0019897--C:extrinsic component of plasma membrane
GO:0030496--C:midbody
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007032--P:endosome organization
GO:0000281--P:mitotic cytokinesis
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	65.29	6.00e-163	568.00
IUUC-Apl-003226	Anas platyrhynchos	71.19	9.00e-169	587.00
IUUC-Aca-004936	Anolis carolinensis	65.29	0.00e+00	936.00
IUUC-Ame-011029	Astyanax mexicanus	61.32	2.00e-73	268.00
IUUC-Bta-013008	Bos taurus	63.37	5.00e-161	561.00
IUUC-Cja-019173	Callithrix jacchus	66.67	0.00e+00	1026.00
IUUC-Cfa-021243	Canis familiaris	65.56	1.00e-164	573.00
IUUC-Cpo-021522	Cavia porcellus	68.63	0.00e+00	1026.00
IUUC-Csa-023616	Chlorocebus sabaeus	74.71	1.00e-132	467.00
IUUC-Cho-024381	Choloepus hoffmanni	61.35	0.00e+00	986.00
IUUC-Dre-028440	Danio rerio	59.75	2.00e-103	370.00
IUUC-Dno-029039	Dasypus novemcinctus	66.85	0.00e+00	1046.00
IUUC-Dor-031043	Dipodomys ordii	75.90	4.00e-56	213.00
IUUC-Ete-033040	Echinops telfairi	63.86	0.00e+00	971.00
IUUC-Eca-033449	Equus caballus	67.15	2.00e-164	573.00
IUUC-Eeu-034693	Erinaceus europaeus	80.31	1.00e-83	304.00
IUUC-Fca-035794	Felis catus	89.02	4.00e-122	431.00
IUUC-Fal-037322	Ficedula albicollis	69.03	0.00e+00	1079.00
IUUC-Gmo-038584	Gadus morhua	53.99	3.00e-75	276.00
IUUC-Gga-041188	Gallus gallus	72.69	0.00e+00	643.00
IUUC-Gac-041850	Gasterosteus aculeatus	51.02	4.00e-104	372.00
IUUC-Ggo-045565	Gorilla gorilla	65.90	6.00e-173	601.00
IUUC-Hsa-046438	Homo sapiens	66.11	2.00e-173	602.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	68.99	0.00e+00	1028.00
IUUC-Lch-050485	Latimeria chalumnae	72.33	3.00e-126	446.00
IUUC-Loc-052769	Lepisosteus oculatus	54.02	6.00e-116	411.00
IUUC-Laf-053432	Loxodonta africana	85.77	3.00e-130	459.00
IUUC-Mcc-055823	Macaca mulatta	65.90	3.00e-174	605.00
IUUC-Mga-059739	Meleagris gallopavo	73.05	0.00e+00	657.00
IUUC-Mmr-061158	Microcebus murinus	65.90	7.00e-168	584.00
IUUC-Mdo-061801	Monodelphis domestica	68.91	2.00e-161	563.00
IUUC-Mmu-063665	Mus musculus	65.68	0.00e+00	985.00
IUUC-Mpu-066738	Mustela putorius furo	66.37	0.00e+00	1009.00
IUUC-Mlu-067307	Myotis lucifugus	64.16	0.00e+00	992.00
IUUC-Nle-069314	Nomascus leucogenys	66.11	6.00e-174	604.00
IUUC-Opr-070378	Ochotona princeps	74.19	9.00e-136	478.00
IUUC-Ont-071545	Oreochromis niloticus	67.27	4.00e-103	369.00
IUUC-Oan-073537	Ornithorhynchus anatinus	67.01	4.00e-159	555.00
IUUC-Ocu-074193	Oryctolagus cuniculus	67.83	0.00e+00	1053.00
IUUC-Ola-086622	Oryzias latipes	67.03	3.00e-100	359.00
IUUC-Oga-088271	Otolemur garnettii	63.11	1.00e-161	563.00
IUUC-Oar-090431	Ovis aries	63.60	7.00e-161	561.00
IUUC-Ptr-091339	Pan troglodytes	65.72	0.00e+00	1050.00
IUUC-Pan-091783	Papio anubis	65.90	2.00e-175	608.00
IUUC-Pfo-096463	Poecilia formosa	52.09	6.00e-106	378.00
IUUC-Pab-097645	Pongo abelii	66.32	6.00e-174	604.00
IUUC-Pva-103222	Pteropus vampyrus	58.89	2.00e-168	586.00
IUUC-Rno-105510	Rattus norvegicus	66.02	0.00e+00	1019.00
IUUC-Sha-106879	Sarcophilus harrisii	68.00	5.00e-159	555.00
IUUC-Sar-113019	Sorex araneus	62.02	0.00e+00	934.00
IUUC-Ssc-116334	Sus scrofa	68.10	0.00e+00	1046.00
IUUC-Tgu-117062	Taeniopygia guttata	68.08	4.00e-165	575.00
IUUC-Tru-117908	Takifugu rubripes	52.48	0.00e+00	777.00
IUUC-Tsy-118867	Tarsius syrichta	75.15	6.00e-133	468.00
IUUC-Tni-120206	Tetraodon nigroviridis	49.16	1.00e-104	374.00
IUUC-Tbe-127877	Tupaia belangeri	61.29	2.00e-59	224.00
IUUC-Ttr-128580	Tursiops truncatus	73.41	3.00e-140	492.00
IUUC-Vpa-130541	Vicugna pacos	67.15	5.00e-173	601.00
IUUC-Xtr-132161	Xenopus tropicalis	76.92	9.00e-123	434.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence