iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033254

UUCD1 version

UUC-EqC-00363

Ensembl Protein ID

ENSECAP00000001453.1

UniProt Accession

F6W4M2; F6W4M2_HORSE

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000001100.1	ENSECAT00000002034.1	ENSECAP00000001453.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-40	133.4	11	43
E3 activity/RING/U-box	2.50e-24	85.3	403	474
UBD/Beta-Prp	3.00e-53	181.1	7	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+t+++++l+++ 
   Q: 11   HDDDVNCCAFSSALLATCSLDKTVRLYSLSDFS 43
           9*********5599**************98875 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           vp+ef+CpI+ elM++Pv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 403  VPDEFICPITRELMKEPVIASDGYSYEKEAMENWISKKKRTSPMTNLVLPSVVLIPNRTLKMAINRWLETHQ 474
           8********************************************************************997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h+++v +  +f  ++ llat s d+t++++++++ +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHDDDVNC-CAF--SSALLATCSLDKTVRLYSLSDFSElpHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTQNGQTLAVM 92
           66666666655.889..9********************777667789****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w+ ++++ ++ + s++dg+    ++ p+g l+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCQFSPDSTCLVSGAADGTVVMWNAQSYKLYR-CGSVKDGSLVACAFCPTGTLFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           9765267*********************************9.**********************************8.6678888877. PP
   S: 179  htdsvyslsfdsng.........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+          ++l+s+++d ++k+w ++
   Q: 179  HDLGITCCDFSSQPisdgeqthfFRLASCGQDCQIKMWVVS 219
           *********9998899999*******************776 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVKLIHTLAD HDDDVNCCAF SSALLATCSL DKTVRLYSLS DFSELPHSPL KFHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTQNGQTLA VMEQPSGSPV RVCQFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGGATAT TTTACTTCAA ATAAAGAACA TGGTGAAACT AATTCACACG TTAGCCGATC 60
ATGATGATGA TGTCAACTGC TGTGCGTTCT CCTCTGCCCT CTTGGCTACT TGCTCCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ecb:100051049

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	50.75	8.00e-17	82.40
IUUC-Aml-001614	Ailuropoda melanoleuca	91.39	0.00e+00	910.00
IUUC-Apl-003529	Anas platyrhynchos	74.37	0.00e+00	750.00
IUUC-Aca-004257	Anolis carolinensis	69.40	0.00e+00	704.00
IUUC-Ame-011357	Astyanax mexicanus	51.57	4.00e-115	408.00
IUUC-Bta-013032	Bos taurus	87.42	0.00e+00	874.00
IUUC-Cja-018743	Callithrix jacchus	90.13	0.00e+00	895.00
IUUC-Cfa-021197	Canis familiaris	90.13	0.00e+00	901.00
IUUC-Cpo-022279	Cavia porcellus	87.61	0.00e+00	876.00
IUUC-Csa-023954	Chlorocebus sabaeus	90.55	0.00e+00	903.00
IUUC-Cho-025083	Choloepus hoffmanni	74.01	6.00e-160	556.00
IUUC-Cin-025786	Ciona intestinalis	33.87	2.00e-79	289.00
IUUC-Dre-028087	Danio rerio	56.29	3.00e-144	504.00
IUUC-Dno-028919	Dasypus novemcinctus	91.60	0.00e+00	914.00
IUUC-Dor-031112	Dipodomys ordii	85.50	0.00e+00	848.00
IUUC-Ete-032405	Echinops telfairi	86.59	7.00e-180	622.00
IUUC-Eeu-034545	Erinaceus europaeus	84.24	0.00e+00	821.00
IUUC-Fca-035482	Felis catus	92.02	0.00e+00	912.00
IUUC-Fal-036976	Ficedula albicollis	60.08	3.00e-159	554.00
IUUC-Gmo-039213	Gadus morhua	54.83	2.00e-137	481.00
IUUC-Gga-040561	Gallus gallus	72.96	0.00e+00	733.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.05	9.00e-142	496.00
IUUC-Ggo-045503	Gorilla gorilla	90.34	0.00e+00	901.00
IUUC-Hsa-045910	Homo sapiens	90.34	0.00e+00	901.00
IUUC-Hvu-047757	Hordeum vulgare	43.96	1.00e-18	88.20
IUUC-Itr-048214	Ictidomys tridecemlineatus	86.21	0.00e+00	677.00
IUUC-Loc-052307	Lepisosteus oculatus	58.05	5.00e-167	580.00
IUUC-Laf-053587	Loxodonta africana	89.92	0.00e+00	896.00
IUUC-Mcc-055679	Macaca mulatta	90.34	0.00e+00	902.00
IUUC-Meu-055962	Macropus eugenii	71.22	0.00e+00	658.00
IUUC-Mga-059652	Meleagris gallopavo	72.54	0.00e+00	737.00
IUUC-Mmr-060943	Microcebus murinus	88.08	0.00e+00	873.00
IUUC-Mdo-062592	Monodelphis domestica	83.30	0.00e+00	836.00
IUUC-Mmu-063577	Mus musculus	79.58	0.00e+00	798.00
IUUC-Mpu-066422	Mustela putorius furo	90.13	0.00e+00	892.00
IUUC-Mlu-067250	Myotis lucifugus	89.71	0.00e+00	888.00
IUUC-Nle-069517	Nomascus leucogenys	90.13	0.00e+00	899.00
IUUC-Opr-070776	Ochotona princeps	86.34	0.00e+00	861.00
IUUC-Ont-071821	Oreochromis niloticus	57.02	2.00e-152	532.00
IUUC-Oan-073706	Ornithorhynchus anatinus	81.26	0.00e+00	820.00
IUUC-Ocu-074766	Oryctolagus cuniculus	80.00	0.00e+00	776.00
IUUC-Obr-076354	Oryza brachyantha	51.39	1.00e-18	87.40
IUUC-Ola-086531	Oryzias latipes	55.91	6.00e-147	513.00
IUUC-Oga-088388	Otolemur garnettii	88.03	0.00e+00	875.00
IUUC-Oar-089748	Ovis aries	87.84	0.00e+00	873.00
IUUC-Ptr-090616	Pan troglodytes	90.06	0.00e+00	893.00
IUUC-Pan-091769	Papio anubis	89.24	0.00e+00	639.00
IUUC-Psi-093334	Pelodiscus sinensis	77.73	0.00e+00	740.00
IUUC-Pma-094383	Petromyzon marinus	48.73	9.00e-134	469.00
IUUC-Pfo-096801	Poecilia formosa	55.02	6.00e-146	510.00
IUUC-Pab-098139	Pongo abelii	89.18	0.00e+00	722.00
IUUC-Pca-100523	Procavia capensis	75.21	0.00e+00	728.00
IUUC-Pva-102286	Pteropus vampyrus	88.66	0.00e+00	853.00
IUUC-Rno-104831	Rattus norvegicus	81.72	0.00e+00	811.00
IUUC-Sha-107499	Sarcophilus harrisii	82.77	0.00e+00	830.00
IUUC-Sar-113389	Sorex araneus	85.29	0.00e+00	828.00
IUUC-Tgu-116769	Taeniopygia guttata	71.43	0.00e+00	712.00
IUUC-Tru-118774	Takifugu rubripes	53.40	1.00e-139	489.00
IUUC-Tsy-119595	Tarsius syrichta	77.91	4.00e-180	623.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.14	7.00e-147	513.00
IUUC-Tbe-127938	Tupaia belangeri	78.69	3.00e-140	490.00
IUUC-Ttr-128193	Tursiops truncatus	89.39	0.00e+00	755.00
IUUC-Vpa-130275	Vicugna pacos	90.76	0.00e+00	897.00
IUUC-Xtr-131982	Xenopus tropicalis	59.49	1.00e-166	579.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence