iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-020010

Ensembl Protein ID

ENSCJAP00000021842.2

UniProt Accession

F6RJ57; F6RJ57_CALJA

Genbank Protein ID

JAB09041.1; JAB30146.1; JAB40012.1; JAB44887.1; JAB44888.1; JAB44889.1; JAB44890.1; JAB44891.1

Protein Name

CD2-associated protein

Genbank Nucleotide ID

ACFV01029548; GAMR01003786; GAMQ01001839; GAMP01007868; GAMP01007867; GAMP01007866; GAMP01007865; GAMP01007864

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000011867.2	ENSCJAT00000023079.2	ENSCJAP00000021835.2
ENSCJAG00000011867.2	ENSCJAT00000023086.2	ENSCJAP00000021842.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.40e-67	223.8	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF ++++
   Q: 270  AKEYCRTLFAYESTNEDELTFKEGEIIHLISKETGEAGWWKG--ELNGKEGVFPDNFAVQIS 329
           689***************************************..9*************9986 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
TEFKDDSLPI RRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGTGGGT CTCCACCGTA GACTTGGAGG TCGCCTTCTC TAACTTCTAG TACTAAGGGA 60
GGGGCGAGGG GCGAGGGGCG AGGGGCGGGC TCCGAGGCTG GGTGGGTGCT CCGGGTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

KEGG

cjc:100386627

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	88.14	0.00e+00	959.00
IUUC-Apl-003573	Anas platyrhynchos	63.07	5.00e-159	554.00
IUUC-Aca-005118	Anolis carolinensis	63.84	3.00e-165	575.00
IUUC-Ame-010657	Astyanax mexicanus	55.06	7.00e-90	324.00
IUUC-Bta-012577	Bos taurus	85.54	0.00e+00	859.00
IUUC-Cfa-020040	Canis familiaris	90.75	0.00e+00	950.00
IUUC-Cpo-021906	Cavia porcellus	81.80	0.00e+00	799.00
IUUC-Csa-024008	Chlorocebus sabaeus	93.11	0.00e+00	945.00
IUUC-Cho-024359	Choloepus hoffmanni	56.88	6.00e-78	285.00
IUUC-Cin-025154	Ciona intestinalis	59.26	2.00e-13	67.00
IUUC-Csv-026228	Ciona savignyi	39.75	4.00e-24	103.00
IUUC-Dre-027661	Danio rerio	54.76	5.00e-92	332.00
IUUC-Dno-029568	Dasypus novemcinctus	86.27	0.00e+00	860.00
IUUC-Dor-030286	Dipodomys ordii	76.18	0.00e+00	707.00
IUUC-Ete-032576	Echinops telfairi	66.61	3.00e-177	614.00
IUUC-Eca-033438	Equus caballus	89.05	0.00e+00	966.00
IUUC-Eeu-034588	Erinaceus europaeus	72.19	2.00e-149	522.00
IUUC-Fca-036597	Felis catus	89.55	0.00e+00	976.00
IUUC-Fal-037305	Ficedula albicollis	63.80	7.00e-164	570.00
IUUC-Gmo-039516	Gadus morhua	45.75	1.00e-65	244.00
IUUC-Gga-040979	Gallus gallus	64.68	1.00e-176	613.00
IUUC-Gac-041945	Gasterosteus aculeatus	51.45	8.00e-79	288.00
IUUC-Ggo-044488	Gorilla gorilla	94.05	0.00e+00	990.00
IUUC-Hsa-045909	Homo sapiens	93.74	0.00e+00	985.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	91.17	3.00e-124	437.00
IUUC-Lch-049481	Latimeria chalumnae	54.39	5.00e-154	538.00
IUUC-Loc-052715	Lepisosteus oculatus	51.72	3.00e-143	502.00
IUUC-Laf-053444	Loxodonta africana	85.02	0.00e+00	900.00
IUUC-Mcc-054844	Macaca mulatta	93.27	0.00e+00	946.00
IUUC-Meu-056491	Macropus eugenii	64.77	2.00e-177	615.00
IUUC-Mga-060154	Meleagris gallopavo	65.33	1.00e-175	609.00
IUUC-Mmr-061099	Microcebus murinus	89.67	0.00e+00	913.00
IUUC-Mdo-062769	Monodelphis domestica	71.19	0.00e+00	766.00
IUUC-Mmu-063136	Mus musculus	84.66	0.00e+00	787.00
IUUC-Mpu-066509	Mustela putorius furo	89.19	0.00e+00	884.00
IUUC-Mlu-067174	Myotis lucifugus	85.65	0.00e+00	879.00
IUUC-Nle-070147	Nomascus leucogenys	93.90	0.00e+00	995.00
IUUC-Opr-070752	Ochotona princeps	80.60	6.00e-166	577.00
IUUC-Ont-071810	Oreochromis niloticus	55.94	4.00e-101	362.00
IUUC-Oan-072731	Ornithorhynchus anatinus	73.28	8.00e-170	590.00
IUUC-Ocu-074331	Oryctolagus cuniculus	88.94	0.00e+00	897.00
IUUC-Ola-086404	Oryzias latipes	45.74	6.00e-89	321.00
IUUC-Oga-088200	Otolemur garnettii	89.83	0.00e+00	997.00
IUUC-Oar-090423	Ovis aries	83.83	0.00e+00	827.00
IUUC-Ptr-091230	Pan troglodytes	94.05	0.00e+00	992.00
IUUC-Pan-091823	Papio anubis	93.11	0.00e+00	943.00
IUUC-Psi-093127	Pelodiscus sinensis	62.58	2.00e-162	565.00
IUUC-Pfo-096539	Poecilia formosa	48.67	2.00e-86	313.00
IUUC-Pab-097666	Pongo abelii	94.05	0.00e+00	981.00
IUUC-Pca-100812	Procavia capensis	81.04	2.00e-131	463.00
IUUC-Pva-102260	Pteropus vampyrus	81.02	0.00e+00	763.00
IUUC-Rno-106038	Rattus norvegicus	84.04	0.00e+00	820.00
IUUC-Sha-106975	Sarcophilus harrisii	71.63	0.00e+00	724.00
IUUC-Sar-113386	Sorex araneus	86.59	8.00e-108	384.00
IUUC-Ssc-115569	Sus scrofa	90.69	4.00e-113	400.00
IUUC-Tgu-117104	Taeniopygia guttata	63.96	4.00e-177	614.00
IUUC-Tru-117649	Takifugu rubripes	50.25	1.00e-95	343.00
IUUC-Tsy-119258	Tarsius syrichta	80.88	0.00e+00	826.00
IUUC-Tni-120755	Tetraodon nigroviridis	44.93	2.00e-122	432.00
IUUC-Tbe-127842	Tupaia belangeri	70.33	0.00e+00	646.00
IUUC-Ttr-129205	Tursiops truncatus	87.67	0.00e+00	804.00
IUUC-Vpa-130434	Vicugna pacos	85.10	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence