iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117988

Ensembl Protein ID

ENSTRUP00000012244.1

UniProt Accession

H2SIL2; H2SIL2_TAKRU

Protein Name

Histone-lysine N-methyltransferase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005108.1	ENSTRUT00000012304.1	ENSTRUP00000012244.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.90e-19	69.8	22	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 1    ekvClvCgeggedekslveCek.CrewfHpaClklsveeelpnsekwiCpkCrs 53
           e++C vC+++ge    l+ Ce  C+ +fH aC +l+   e p+ + +iCp+C+s
   Q: 22   ENICQVCEKTGE----LLLCEGqCCGAFHLACISLA---EAPKGK-FICPECKS 67
           589*********....*****99*************...999997.******86 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

DDTLSPSRKI IGDRGGPASM KENICQVCEK TGELLLCEGQ CCGAFHLACI SLAEAPKGKF 60
ICPECKSGIH TCFVCKKRSE DVRRCMIPVC GKFYHGECIA NFAPTVAVNR GFRCSIHVCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGACACAC TTTCACCTTC AAGGAAGATC ATAGGAGATC GAGGCGGCCC CGCTTCCATG 60
AAGGAGAACA TATGTCAGGT GAGCTTCGCT GCAAGATCTG TTTAACTGAG AGCTCTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001795	Ailuropoda melanoleuca	77.71	0.00e+00	1203.00
IUUC-Apl-003953	Anas platyrhynchos	77.57	0.00e+00	1163.00
IUUC-Aca-005339	Anolis carolinensis	77.54	0.00e+00	1203.00
IUUC-Bta-012966	Bos taurus	78.43	0.00e+00	1204.00
IUUC-Cja-018780	Callithrix jacchus	74.86	0.00e+00	1199.00
IUUC-Cfa-020975	Canis familiaris	77.71	0.00e+00	1204.00
IUUC-Cpo-021331	Cavia porcellus	77.64	0.00e+00	1187.00
IUUC-Csa-024226	Chlorocebus sabaeus	75.00	0.00e+00	1200.00
IUUC-Csv-026298	Ciona savignyi	37.76	7.00e-58	218.00
IUUC-Dre-027488	Danio rerio	81.05	0.00e+00	1244.00
IUUC-Dno-029230	Dasypus novemcinctus	74.12	0.00e+00	1135.00
IUUC-Dor-031016	Dipodomys ordii	68.83	0.00e+00	922.00
IUUC-Eca-033591	Equus caballus	78.19	0.00e+00	1201.00
IUUC-Fca-035791	Felis catus	77.71	0.00e+00	1204.00
IUUC-Fal-037378	Ficedula albicollis	76.94	0.00e+00	1167.00
IUUC-Gmo-038919	Gadus morhua	81.23	0.00e+00	1003.00
IUUC-Gga-040881	Gallus gallus	77.09	0.00e+00	1174.00
IUUC-Gac-041378	Gasterosteus aculeatus	92.89	0.00e+00	1171.00
IUUC-Hsa-046436	Homo sapiens	75.00	0.00e+00	1202.00
IUUC-Itr-048194	Ictidomys tridecemlineatus	77.71	0.00e+00	1204.00
IUUC-Lch-049684	Latimeria chalumnae	77.29	0.00e+00	1144.00
IUUC-Laf-054046	Loxodonta africana	78.43	0.00e+00	1200.00
IUUC-Mcc-055593	Macaca mulatta	75.00	0.00e+00	1202.00
IUUC-Mga-059756	Meleagris gallopavo	77.49	0.00e+00	1172.00
IUUC-Mmr-061182	Microcebus murinus	77.57	0.00e+00	1204.00
IUUC-Mdo-061984	Monodelphis domestica	75.53	0.00e+00	1149.00
IUUC-Mmu-063605	Mus musculus	78.43	0.00e+00	1215.00
IUUC-Mpu-066446	Mustela putorius furo	77.71	0.00e+00	1204.00
IUUC-Mlu-067261	Myotis lucifugus	77.71	0.00e+00	1205.00
IUUC-Nle-069818	Nomascus leucogenys	77.43	0.00e+00	1191.00
IUUC-Opr-070842	Ochotona princeps	73.20	0.00e+00	1092.00
IUUC-Oan-073496	Ornithorhynchus anatinus	77.86	0.00e+00	1185.00
IUUC-Ocu-074918	Oryctolagus cuniculus	77.34	0.00e+00	1209.00
IUUC-Obr-076122	Oryza brachyantha	27.98	3.00e-11	62.40
IUUC-Ogl-077641	Oryza glaberrima	27.23	5.00e-11	61.60
IUUC-Ogu-078898	Oryza glumaepatula	27.23	5.00e-11	61.60
IUUC-Oin-079557	Oryza indica	27.23	5.00e-11	61.60
IUUC-Osa-085353	Oryza sativa	27.23	5.00e-11	62.00
IUUC-Oga-088743	Otolemur garnettii	75.52	0.00e+00	1206.00
IUUC-Oar-090265	Ovis aries	78.43	0.00e+00	1204.00
IUUC-Ptr-090521	Pan troglodytes	75.00	0.00e+00	1202.00
IUUC-Psi-093245	Pelodiscus sinensis	76.50	0.00e+00	1165.00
IUUC-Pfo-096066	Poecilia formosa	91.87	0.00e+00	1357.00
IUUC-Pab-098644	Pongo abelii	75.00	0.00e+00	1199.00
IUUC-Pva-103094	Pteropus vampyrus	81.24	0.00e+00	1013.00
IUUC-Rno-105803	Rattus norvegicus	78.22	0.00e+00	1219.00
IUUC-Sha-107278	Sarcophilus harrisii	77.78	0.00e+00	1199.00
IUUC-Sar-113402	Sorex araneus	76.58	0.00e+00	919.00
IUUC-Sbi-114581	Sorghum bicolor	32.46	4.00e-08	52.00
IUUC-Ssc-116193	Sus scrofa	78.29	0.00e+00	1198.00
IUUC-Tgu-116532	Taeniopygia guttata	77.88	0.00e+00	1064.00
IUUC-Tsy-118830	Tarsius syrichta	77.86	0.00e+00	1197.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence