iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087173

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04027198

Gene Name

trip12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000011737.2	ENSORLT00000014713.2	ENSORLP00000014712.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.70e-97	326.5	1642	2021

Active Site

Position(s)	Description	Evidence
1988	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.......................ehlk 69
           ++ le+++++E g++l G+t+ef+al+s+elq++dlgl++ +e   ++ + n++     +                       +   
   Q: 1642 RAMLEIQYENEVGTGL-GPTQEFYALVSQELQRADLGLWRGEEVTLTNPKGNQEGT---KymfssrglfavpfgrttkpahiaKIKM 1724
           56899***********.**********************65555444444333322...12355667788889*********99999 PP
   S: 70   lFeflGrllgkalqdgrlldlplsksfyklllgk..klsledleevdpelykslkeikenaes........................ 130
            F+flG+l++ka++d rlldlpl  +fyk +l++  ++s +dl ++dp ++ks++ +++   +                        
   Q: 1725 KFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHetSVSSHDLVNIDPGVAKSIQHLEDIIRQkkrleqdrsqtretlqqaleslnm 1811
           9*********************************444666******************99833445555666667777544444444 PP
   S: 131  ...dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslF 209
              ++e+            +     l+   + eLk gG+++ Vt+ N+eeY +lvv ++l+eg+ +q+e+freGf++v+pl++l++F
   Q: 1812 ngcSVED------------LgldftLPGFPNIELKKGGKDVAVTIYNLEEYLRLVVYWTLNEGVSRQFESFREGFESVFPLHHLQYF 1886
           4444444............34455578999********************************************************* PP
   S: 210  teeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk... 291
            +eel++l+cG+  e++dv++l + ++ ++gyt+ds+ai++++evl++f++e+++ fLqFvTgs+rlP+gGf++l+p l+++rk   
   Q: 1887 YPEELDQLLCGSksETWDVKTLMECCRPDHGYTHDSRAIRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKtfe 1973
           ***********98889*********************************************************************** PP
   S: 292  ..dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
             ++ dd lPs++TC+nyLkLP+Yss ei++ekLl+A +e+ ++F+ls
   Q: 1974 stENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGqQSFHLS 2021
           988888***************************************985 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MSNRPNSNPG GSLRRSQRNT AAAQPQDHTV AGRSGLTLSV ASFVLQDDPE TAGTSEQERS 60
GHFSKSEGTR GLKRSEAPDQ ISVLGPTPSK KSKPIHQPRD NTSETKKGPA KSKKRPVASD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTTGCCCT GTCTGTTACA ACTACAACAC TGGAACAAAT AGGTAACAAC ATTCGGTCAA 60
ATGTTGAATT TGACAACATT GACATCTCGA CCAACAGTAT TTGTAGATTT TCAGGTTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr

PROSITE

PS50237--HECT
PS50918--WWE

Pfam

PF00632--HECT
PF02825--WWE

SMART

SM00119--HECTc
SM00678--WWE

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.23	2.00e-127	451.00
IUUC-Aml-001502	Ailuropoda melanoleuca	80.40	0.00e+00	3018.00
IUUC-Atr-002821	Amborella trichopoda	38.01	1.00e-119	424.00
IUUC-Apl-003531	Anas platyrhynchos	79.85	0.00e+00	2934.00
IUUC-Aly-005962	Arabidopsis lyrata	39.02	4.00e-117	416.00
IUUC-Ath-006636	Arabidopsis thaliana	38.88	7.00e-118	419.00
IUUC-Ago-007875	Ashbya gossypii	36.45	1.00e-81	298.00
IUUC-Acl-008242	Aspergillus clavatus	36.42	2.00e-116	414.00
IUUC-Afl-008736	Aspergillus flavus	39.82	6.00e-115	409.00
IUUC-Afu-008812	Aspergillus fumigatus	36.87	2.00e-118	421.00
IUUC-Ani-009407	Aspergillus nidulans	37.89	4.00e-113	403.00
IUUC-Ang-009763	Aspergillus niger	40.04	6.00e-108	386.00
IUUC-Aor-009941	Aspergillus oryzae	31.58	1.00e-118	421.00
IUUC-Ate-010459	Aspergillus terreus	38.25	1.00e-89	325.00
IUUC-Bgr-012265	Blumeria graminis	35.26	3.00e-106	380.00
IUUC-Bta-013070	Bos taurus	81.12	0.00e+00	3043.00
IUUC-Bci-013890	Botrytis cinerea	39.64	8.00e-103	369.00
IUUC-Bdi-014046	Brachypodium distachyon	37.73	2.00e-123	437.00
IUUC-Bol-015942	Brassica oleracea	40.75	1.00e-115	411.00
IUUC-Bra-016849	Brassica rapa	40.75	2.00e-115	411.00
IUUC-Cja-019046	Callithrix jacchus	79.98	0.00e+00	2999.00
IUUC-Cfa-020521	Canis familiaris	79.00	0.00e+00	2920.00
IUUC-Cpo-021639	Cavia porcellus	77.00	0.00e+00	2902.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.42	1.00e-90	326.00
IUUC-Csa-023231	Chlorocebus sabaeus	81.36	0.00e+00	3068.00
IUUC-Cho-024380	Choloepus hoffmanni	79.49	0.00e+00	1878.00
IUUC-Cin-025482	Ciona intestinalis	49.91	1.00e-157	549.00
IUUC-Csv-026121	Ciona savignyi	47.49	0.00e+00	1538.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	34.28	1.00e-108	388.00
IUUC-Cne-026857	Cryptococcus neoformans	39.89	9.00e-95	342.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.12	1.00e-74	275.00
IUUC-Dre-028174	Danio rerio	92.09	0.00e+00	3153.00
IUUC-Dor-030939	Dipodomys ordii	76.13	0.00e+00	2458.00
IUUC-Dse-031444	Dothistroma septosporum	39.27	2.00e-107	384.00
IUUC-Dme-032162	Drosophila melanogaster	59.13	0.00e+00	724.00
IUUC-Ete-032345	Echinops telfairi	78.45	0.00e+00	2020.00
IUUC-Eca-033229	Equus caballus	79.96	0.00e+00	2985.00
IUUC-Eeu-035205	Erinaceus europaeus	71.94	0.00e+00	2592.00
IUUC-Fca-036444	Felis catus	78.62	0.00e+00	2996.00
IUUC-Fal-037131	Ficedula albicollis	81.39	0.00e+00	3073.00
IUUC-Fox-038035	Fusarium oxysporum	35.51	9.00e-108	384.00
IUUC-Fso-038320	Fusarium solani	34.95	1.00e-107	385.00
IUUC-Gmo-039497	Gadus morhua	89.88	0.00e+00	3315.00
IUUC-Ggr-040057	Gaeumannomyces graminis	34.25	6.00e-105	376.00
IUUC-Gga-041021	Gallus gallus	81.58	0.00e+00	3076.00
IUUC-Gac-042474	Gasterosteus aculeatus	91.69	0.00e+00	3399.00
IUUC-Gma-043060	Glycine max	38.97	6.00e-122	432.00
IUUC-Ggo-044855	Gorilla gorilla	80.03	0.00e+00	3000.00
IUUC-Hsa-046147	Homo sapiens	81.12	0.00e+00	3013.00
IUUC-Hvu-047775	Hordeum vulgare	38.37	3.00e-126	447.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	86.91	0.00e+00	2984.00
IUUC-Kpa-049098	Komagataella pastoris	37.10	2.00e-84	308.00
IUUC-Lch-049818	Latimeria chalumnae	86.52	0.00e+00	2910.00
IUUC-Lpe-051017	Leersia perrieri	37.59	2.00e-118	421.00
IUUC-Loc-051777	Lepisosteus oculatus	86.32	0.00e+00	3289.00
IUUC-Lma-052990	Leptosphaeria maculans	35.71	3.00e-114	407.00
IUUC-Laf-053727	Loxodonta africana	79.77	0.00e+00	2974.00
IUUC-Mcc-055799	Macaca mulatta	87.31	0.00e+00	2924.00
IUUC-Meu-056065	Macropus eugenii	81.47	0.00e+00	1874.00
IUUC-Mor-057054	Magnaporthe oryzae	37.27	2.00e-102	368.00
IUUC-Mpo-057417	Magnaporthe poae	37.81	2.00e-104	374.00
IUUC-Mtr-057849	Medicago truncatula	37.07	1.00e-114	408.00
IUUC-Mla-058870	Melampsora laricipopulina	42.08	7.00e-110	392.00
IUUC-Mga-059580	Meleagris gallopavo	79.40	0.00e+00	2570.00
IUUC-Mvi-060507	Microbotryum violaceum	40.91	1.00e-114	408.00
IUUC-Mmr-060816	Microcebus murinus	81.32	0.00e+00	3062.00
IUUC-Mdo-062866	Monodelphis domestica	79.12	0.00e+00	2843.00
IUUC-Mmu-063906	Mus musculus	82.60	0.00e+00	3080.00
IUUC-Mac-064675	Musa acuminata	38.34	2.00e-111	396.00
IUUC-Mpu-066199	Mustela putorius furo	79.86	0.00e+00	2978.00
IUUC-Mlu-067110	Myotis lucifugus	82.50	0.00e+00	3067.00
IUUC-Nfi-068482	Neosartorya fischeri	36.72	2.00e-117	417.00
IUUC-Ncr-068906	Neurospora crassa	37.73	2.00e-105	378.00
IUUC-Nle-069410	Nomascus leucogenys	79.91	0.00e+00	2991.00
IUUC-Opr-070401	Ochotona princeps	74.34	0.00e+00	1702.00
IUUC-Ont-072100	Oreochromis niloticus	92.58	0.00e+00	3501.00
IUUC-Oan-073121	Ornithorhynchus anatinus	81.37	0.00e+00	3112.00
IUUC-Ocu-074623	Oryctolagus cuniculus	79.96	0.00e+00	2987.00
IUUC-Oba-075380	Oryza barthii	31.58	5.00e-114	405.00
IUUC-Obr-076915	Oryza brachyantha	37.16	2.00e-118	421.00
IUUC-Ogl-077055	Oryza glaberrima	37.75	3.00e-119	423.00
IUUC-Ogu-078892	Oryza glumaepatula	31.37	3.00e-113	403.00
IUUC-Oin-079256	Oryza indica	37.71	4.00e-118	420.00
IUUC-Olo-080343	Oryza longistaminata	37.85	5.00e-118	419.00
IUUC-Ome-081422	Oryza meridionalis	37.85	8.00e-118	419.00
IUUC-Oni-083047	Oryza nivara	31.58	8.00e-115	408.00
IUUC-Opu-083641	Oryza punctata	36.16	2.00e-108	387.00
IUUC-Oru-084439	Oryza rufipogon	31.48	7.00e-114	405.00
IUUC-Osa-085972	Oryza sativa	38.03	2.00e-117	416.00
IUUC-Olu-087871	Ostreococcus lucimarinus	37.64	4.00e-89	322.00
IUUC-Oga-087908	Otolemur garnettii	79.55	0.00e+00	2999.00
IUUC-Oar-090277	Ovis aries	82.66	0.00e+00	3110.00
IUUC-Ptr-091543	Pan troglodytes	81.17	0.00e+00	3014.00
IUUC-Pan-092243	Papio anubis	87.26	0.00e+00	2923.00
IUUC-Psi-093150	Pelodiscus sinensis	81.21	0.00e+00	3074.00
IUUC-Pno-094891	Phaeosphaeria nodorum	40.63	1.00e-114	408.00
IUUC-Ppa-095181	Physcomitrella patens	37.34	4.00e-107	382.00
IUUC-Pfo-096267	Poecilia formosa	91.37	0.00e+00	3420.00
IUUC-Pab-098072	Pongo abelii	80.15	0.00e+00	2999.00
IUUC-Pop-099190	Populus trichocarpa	37.14	1.00e-117	418.00
IUUC-Pca-100311	Procavia capensis	75.39	0.00e+00	2724.00
IUUC-Ppe-101284	Prunus persica	38.04	2.00e-118	421.00
IUUC-Pva-102215	Pteropus vampyrus	79.83	0.00e+00	1014.00
IUUC-Pgr-103694	Puccinia graminis	36.01	1.00e-107	385.00
IUUC-Ptt-103916	Puccinia triticina	40.16	2.00e-103	371.00
IUUC-Pte-104346	Pyrenophora teres	40.41	4.00e-112	400.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	40.41	1.00e-111	398.00
IUUC-Rno-105315	Rattus norvegicus	87.26	0.00e+00	2900.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.26	1.00e-70	261.00
IUUC-Sha-106835	Sarcophilus harrisii	79.68	0.00e+00	3092.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.57	5.00e-99	356.00
IUUC-Spo-108081	Schizosaccharomyces pombe	39.21	2.00e-97	351.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	39.44	1.00e-105	379.00
IUUC-Smo-108776	Selaginella moellendorffii	37.45	5.00e-117	416.00
IUUC-Sit-109757	Setaria italica	38.00	1.00e-123	438.00
IUUC-Sly-111469	Solanum lycopersicum	39.14	2.00e-121	431.00
IUUC-Stu-112896	Solanum tuberosum	37.80	1.00e-106	380.00
IUUC-Sar-113224	Sorex araneus	69.50	0.00e+00	1524.00
IUUC-Sbi-114313	Sorghum bicolor	37.86	2.00e-125	444.00
IUUC-Sre-114993	Sporisorium reilianum	33.86	1.00e-102	369.00
IUUC-Ssc-115535	Sus scrofa	79.47	0.00e+00	2966.00
IUUC-Tgu-117493	Taeniopygia guttata	78.85	0.00e+00	2320.00
IUUC-Tru-118669	Takifugu rubripes	87.54	0.00e+00	3255.00
IUUC-Tsy-119373	Tarsius syrichta	80.27	0.00e+00	1615.00
IUUC-Tni-120049	Tetraodon nigroviridis	82.57	0.00e+00	910.00
IUUC-Tca-121779	Theobroma cacao	38.40	2.00e-115	410.00
IUUC-Tre-122195	Trichoderma reesei	35.18	3.00e-104	374.00
IUUC-Tvi-122650	Trichoderma virens	34.72	4.00e-105	377.00
IUUC-Tae-123580	Triticum aestivum	38.29	5.00e-126	445.00
IUUC-Tur-126295	Triticum urartu	38.23	5.00e-127	449.00
IUUC-Tme-126964	Tuber melanosporum	40.64	3.00e-107	384.00
IUUC-Tbe-128149	Tupaia belangeri	73.44	0.00e+00	1111.00
IUUC-Ttr-128165	Tursiops truncatus	83.14	0.00e+00	2732.00
IUUC-Uma-129365	Ustilago maydis	35.17	5.00e-88	320.00
IUUC-Vda-129725	Verticillium dahliae	40.48	7.00e-107	382.00
IUUC-Vpa-130678	Vicugna pacos	84.21	0.00e+00	2382.00
IUUC-Vvi-131147	Vitis vinifera	39.12	6.00e-122	432.00
IUUC-Xtr-132636	Xenopus tropicalis	80.42	0.00e+00	2969.00
IUUC-Xma-133458	Xiphophorus maculatus	91.47	0.00e+00	3472.00
IUUC-Yli-134481	Yarrowia lipolytica	38.11	1.00e-98	355.00
IUUC-Zma-135782	Zea mays	37.89	3.00e-118	420.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence