iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067245

Ensembl Protein ID

ENSMLUP00000021136.1

UniProt Accession

G1QBQ3; G1QBQ3_MYOLU

Genbank Protein ID

ENSMLUP00000021136

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAPE02038655

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000026057.1	ENSMLUT00000030419.1	ENSMLUP00000021136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-09	37.7	124	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 124  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 170
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

FLETLKEIDD VYEKYKKEDD SNQKKRLQQH LQRALINSQE LGDEKIQIVT QMLELVENRA 60
RQMELHSQCF QDPAESERVS DKAKIDASQP ERSSKSAKKK KRSKAKQERE TSPVEFAIDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTAGAAA CATTAAAGGA AATTGATGAT GTCTATGAAA AATATAAGAA AGAAGATGAT 60
TCAAACCAGA AAAAACGCCT ACAGCAGCAT CTCCAGAGAG CATTAATCAA TAGTCAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	79.02	6.00e-76	277.00
IUUC-Apl-003705	Anas platyrhynchos	73.21	9.00e-78	282.00
IUUC-Aca-004990	Anolis carolinensis	69.51	3.00e-70	258.00
IUUC-Cja-018960	Callithrix jacchus	78.95	2.00e-68	252.00
IUUC-Cfa-020869	Canis familiaris	79.56	2.00e-75	275.00
IUUC-Csa-023304	Chlorocebus sabaeus	78.95	1.00e-68	252.00
IUUC-Dno-029945	Dasypus novemcinctus	80.00	6.00e-76	277.00
IUUC-Dor-030141	Dipodomys ordii	78.05	5.00e-76	277.00
IUUC-Ete-032709	Echinops telfairi	79.11	2.00e-85	308.00
IUUC-Eca-033432	Equus caballus	81.33	1.00e-76	279.00
IUUC-Fal-036700	Ficedula albicollis	73.33	2.00e-78	285.00
IUUC-Gmo-038748	Gadus morhua	57.38	2.00e-67	248.00
IUUC-Gga-040175	Gallus gallus	73.09	2.00e-77	281.00
IUUC-Hsa-045837	Homo sapiens	78.95	1.00e-68	252.00
IUUC-Lch-049965	Latimeria chalumnae	67.11	1.00e-75	276.00
IUUC-Mcc-055155	Macaca mulatta	77.01	6.00e-59	219.00
IUUC-Mga-059570	Meleagris gallopavo	73.09	9.00e-77	279.00
IUUC-Mmr-061385	Microcebus murinus	78.95	2.00e-68	252.00
IUUC-Nle-069968	Nomascus leucogenys	100.00	5.00e-47	180.00
IUUC-Oga-088336	Otolemur garnettii	78.42	6.00e-68	250.00
IUUC-Ptr-091348	Pan troglodytes	100.00	4.00e-47	181.00
IUUC-Pan-092819	Papio anubis	78.95	1.00e-68	252.00
IUUC-Pab-098346	Pongo abelii	78.42	4.00e-68	251.00
IUUC-Sha-107533	Sarcophilus harrisii	76.89	1.00e-81	295.00
IUUC-Sar-113630	Sorex araneus	78.54	8.00e-76	276.00
IUUC-Tgu-117034	Taeniopygia guttata	73.33	3.00e-78	284.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence