• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
UUCD2 ID IUUC-Aml-001575
UUCD1 version UUC-AiM-00468
Ensembl Protein ID ENSAMEP00000007058.1
UniProt Accession G1LJF3; G1LJF3_AILME
Genbank Protein ID ENSAMEP00000007058
Protein Name E3 ubiquitin-protein ligase
Genbank Nucleotide ID ACTA01018935
Gene Name WWP2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000006697.1 ENSAMET00000007355.1 ENSAMEP00000007058.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 2.60e-136 454.5 537 871
Active Site
Position(s) Description Evidence
840 Glycyl thioester intermediate {ECO:0000256|PIRSR:PIRSR001569-1,
ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl++rl+v ++gEegld+gG++re+++lls+e+ np+++lf+y  +++++lq+np+s + np+hl +F+f+Gr++++al++g+++d+
   Q: 537  PYDLRRRLYVIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSI-NPDHLTYFRFIGRFIAMALYHGKFIDT 624
           6799********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk++l+k+ +l+dle++dpe+y+s+ +iken   ++ee+gl+l f ++ eilg+++++eLk+gGe+i+Vt+eNk+eY+ l+++
   Q: 625  GFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKEN---NLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKDEYIMLLTD 710
           ***********************************99...9************************************************ PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+++g++eq++af +Gfnev ple+l++F+e+elel++cG++eid++d++k+t y++ yt++s++iqwFw+v++e+++e+r ++LqFv
   Q: 711  WRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNTIYRH-YTKNSKQIQWFWQVVKEMDNEKRIRLLQFV 798
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk......prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tg++rlP+gGfael       p++f+i k +++++lP+s+TCfn+L+LP+Y+s+e+lkekLlyAieet+gF++
   Q: 799  TGTCRLPVGGFAELIvtgsngPQKFCIDKVGKETWLPRSHTCFNRLDLPPYKSYEQLKEKLLYAIEETEGFGQ 871
           ***********************************************************************96 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MASASSSRAG VALPFEKSQL TLKVVSAKPK VHNRQPRINS FVEVAVDGLP SETKKTGKRI 60
GSSELLWNEI IILNVTAQSH LDLKVWSCHT LRNELLGTAS VNLSNVLKNN GGKMENTQLT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001575|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCATCCG CCAGCTCCAG CCGGGCAGGA GTGGCCCTGC CTTTTGAGAA ATCTCAGCTT 60
ACTTTGAAAG GTGAGTGGCA CCATGTGAAA TGTTTACCAT TCCAGGTCCA GCCCAATCTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001575|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000008--C2_dom
IPR024928--E3_ub_ligase_SMURF1
IPR000569--HECT_dom
IPR001202--WW_dom
PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2
Pfam

PF00632--HECT
PF00397--WW
SMART

SM00239--C2
SM00119--HECTc
SM00456--WW
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0005634--C:nucleus
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0051224--P:negative regulation of protein transport
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0032410--P:negative regulation of transporter activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042391--P:regulation of membrane potential
GO:1901016--P:regulation of potassium ion transmembrane transporter activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003912 Anas platyrhynchos 76.80 0.00e+00 1239.00
IUUC-Aca-004291 Anolis carolinensis 80.60 0.00e+00 1431.00
IUUC-Bta-013231 Bos taurus 95.87 0.00e+00 1617.00
IUUC-Cel-018299 Caenorhabditis elegans 66.95 0.00e+00 827.00
IUUC-Cja-019455 Callithrix jacchus 95.64 0.00e+00 1677.00
IUUC-Cfa-021017 Canis familiaris 97.94 0.00e+00 1649.00
IUUC-Cpo-021988 Cavia porcellus 95.07 0.00e+00 1651.00
IUUC-Csa-023549 Chlorocebus sabaeus 95.64 0.00e+00 1686.00
IUUC-Dre-028513 Danio rerio 91.27 0.00e+00 1131.00
IUUC-Dno-028976 Dasypus novemcinctus 95.99 0.00e+00 1679.00
IUUC-Dor-030176 Dipodomys ordii 92.11 0.00e+00 1501.00
IUUC-Eca-033949 Equus caballus 97.25 0.00e+00 1667.00
IUUC-Eeu-034529 Erinaceus europaeus 89.24 0.00e+00 1391.00
IUUC-Fca-036236 Felis catus 97.48 0.00e+00 1699.00
IUUC-Fal-036948 Ficedula albicollis 78.15 0.00e+00 1333.00
IUUC-Gmo-038842 Gadus morhua 88.58 0.00e+00 1064.00
IUUC-Gga-040617 Gallus gallus 79.80 0.00e+00 1429.00
IUUC-Gac-041338 Gasterosteus aculeatus 69.46 0.00e+00 1244.00
IUUC-Ggo-045278 Gorilla gorilla 96.10 0.00e+00 1690.00
IUUC-Hsa-046148 Homo sapiens 96.10 0.00e+00 1690.00
IUUC-Itr-047945 Ictidomys tridecemlineatus 97.77 0.00e+00 1118.00
IUUC-Lch-050663 Latimeria chalumnae 78.19 0.00e+00 1385.00
IUUC-Loc-052604 Lepisosteus oculatus 75.37 0.00e+00 1308.00
IUUC-Laf-053944 Loxodonta africana 96.22 0.00e+00 1676.00
IUUC-Mcc-055655 Macaca mulatta 95.76 0.00e+00 1687.00
IUUC-Meu-055953 Macropus eugenii 79.98 0.00e+00 1380.00
IUUC-Mga-060190 Meleagris gallopavo 80.41 0.00e+00 1431.00
IUUC-Mmr-060896 Microcebus murinus 95.96 0.00e+00 1632.00
IUUC-Mdo-062536 Monodelphis domestica 91.08 0.00e+00 1612.00
IUUC-Mmu-064017 Mus musculus 94.84 0.00e+00 1641.00
IUUC-Mpu-066608 Mustela putorius furo 95.19 0.00e+00 1607.00
IUUC-Mlu-067623 Myotis lucifugus 93.47 0.00e+00 1605.00
IUUC-Nle-069496 Nomascus leucogenys 93.93 0.00e+00 1636.00
IUUC-Opr-071054 Ochotona princeps 83.90 0.00e+00 1419.00
IUUC-Ont-071279 Oreochromis niloticus 73.80 0.00e+00 1278.00
IUUC-Oan-073512 Ornithorhynchus anatinus 88.32 0.00e+00 1491.00
IUUC-Ocu-074271 Oryctolagus cuniculus 94.64 0.00e+00 1614.00
IUUC-Ola-087237 Oryzias latipes 69.17 0.00e+00 1226.00
IUUC-Oga-088164 Otolemur garnettii 96.10 0.00e+00 1680.00
IUUC-Oar-089698 Ovis aries 96.22 0.00e+00 1629.00
IUUC-Ptr-091306 Pan troglodytes 94.95 0.00e+00 1660.00
IUUC-Pan-092814 Papio anubis 92.11 0.00e+00 1596.00
IUUC-Pfo-096709 Poecilia formosa 72.12 0.00e+00 1279.00
IUUC-Pab-098494 Pongo abelii 90.75 0.00e+00 1591.00
IUUC-Pca-100596 Procavia capensis 83.73 0.00e+00 1373.00
IUUC-Pva-103154 Pteropus vampyrus 90.87 0.00e+00 1561.00
IUUC-Rno-104954 Rattus norvegicus 94.20 0.00e+00 1413.00
IUUC-Sha-106781 Sarcophilus harrisii 91.08 0.00e+00 1643.00
IUUC-Ssc-116307 Sus scrofa 84.99 0.00e+00 1451.00
IUUC-Tgu-116530 Taeniopygia guttata 75.92 0.00e+00 1186.00
IUUC-Tru-118287 Takifugu rubripes 88.97 0.00e+00 1063.00
IUUC-Tsy-119097 Tarsius syrichta 82.84 0.00e+00 1221.00
IUUC-Tni-120801 Tetraodon nigroviridis 76.04 0.00e+00 1074.00
IUUC-Tbe-127793 Tupaia belangeri 83.94 0.00e+00 1433.00
IUUC-Ttr-128275 Tursiops truncatus 91.28 0.00e+00 1561.00
IUUC-Xtr-132866 Xenopus tropicalis 85.10 0.00e+00 1127.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved