iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073939

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02068123

Gene Name

TRIM40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015671.2	ENSOCUT00000015669.2	ENSOCUP00000013457.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-07	32.1	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+e++k+   ++ CgH+f++ Cl q++  +k ++s    CPlCr
   Q: 14   CPICQEHLKE-ATSTECGHLFCRGCLtQHV--QKALASDVLCCPLCR 57
           ********99.888************8888..7778999999****8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLPWRDPSHD EGICPICQEH LKEATSTECG HLFCRGCLTQ HVQKALASDV LCCPLCRKPC 60
PECILGIGLV CVSHQKRASS FCEESRCLLC PQCLESPEHK SHSELTIENA ISHYKERLSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTCCCTT GGAGGGACCC CAGCCACGAC GAGGGCATCT GCCCCATCTG CCAGGAGCAT 60
CTGAAGGAGG CCACGAGCAC CGAGTGTGGA CACCTCTTCT GTCGAGGGTG CCTGACCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF00097--zf-C3HC4

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042177--P:negative regulation of protein catabolic process
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001427	Ailuropoda melanoleuca	57.03	1.00e-58	219.00
IUUC-Bta-012543	Bos taurus	54.35	2.00e-56	211.00
IUUC-Cja-018793	Callithrix jacchus	60.47	6.00e-68	250.00
IUUC-Csa-023101	Chlorocebus sabaeus	64.57	2.00e-78	285.00
IUUC-Cho-024926	Choloepus hoffmanni	56.34	1.00e-18	86.70
IUUC-Dno-029338	Dasypus novemcinctus	47.22	4.00e-43	167.00
IUUC-Dor-030164	Dipodomys ordii	67.40	3.00e-72	264.00
IUUC-Dse-031337	Dothistroma septosporum	31.58	9.00e-08	50.80
IUUC-Ete-032446	Echinops telfairi	46.91	8.00e-48	183.00
IUUC-Eca-034042	Equus caballus	69.79	9.00e-73	266.00
IUUC-Eeu-034444	Erinaceus europaeus	51.36	4.00e-58	217.00
IUUC-Ggo-044410	Gorilla gorilla	71.65	4.00e-81	294.00
IUUC-Hsa-045978	Homo sapiens	70.87	1.00e-79	289.00
IUUC-Itr-048126	Ictidomys tridecemlineatus	61.92	7.00e-71	259.00
IUUC-Laf-054019	Loxodonta africana	56.64	2.00e-49	188.00
IUUC-Mcc-054616	Macaca mulatta	73.23	4.00e-94	337.00
IUUC-Meu-055981	Macropus eugenii	37.39	3.00e-32	131.00
IUUC-Mdo-062958	Monodelphis domestica	44.39	7.00e-38	150.00
IUUC-Mmu-063571	Mus musculus	62.61	2.00e-67	248.00
IUUC-Nle-069843	Nomascus leucogenys	68.52	1.00e-32	131.00
IUUC-Opr-071083	Ochotona princeps	67.58	5.00e-85	306.00
IUUC-Oga-088040	Otolemur garnettii	71.48	3.00e-85	307.00
IUUC-Oar-089914	Ovis aries	59.77	4.00e-71	261.00
IUUC-Ptr-091240	Pan troglodytes	64.57	3.00e-69	254.00
IUUC-Pan-092095	Papio anubis	73.01	5.00e-82	296.00
IUUC-Pab-098406	Pongo abelii	71.65	6.00e-82	296.00
IUUC-Pca-101043	Procavia capensis	61.57	1.00e-66	245.00
IUUC-Pva-102651	Pteropus vampyrus	64.96	6.00e-82	296.00
IUUC-Rno-106090	Rattus norvegicus	61.30	9.00e-65	239.00
IUUC-Ssc-115942	Sus scrofa	62.11	2.00e-75	275.00
IUUC-Tsy-119497	Tarsius syrichta	69.60	1.00e-80	292.00
IUUC-Tbe-127279	Tupaia belangeri	64.82	9.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence