iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117314

Ensembl Protein ID

ENSTGUP00000001567.1

UniProt Accession

H0YTF4; H0YTF4_TAEGU

Genbank Protein ID

ENSTGUP00000001567

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01035609

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001516.1	ENSTGUT00000001581.1	ENSTGUP00000001567.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	7.10e-19	68.0	101	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 4    eyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfref 72
             r+ll++   +    +d++ ++  y+  +l+e e+ +il+ +e   ++++ ++L+++L  ++ke+W++ +
   Q: 101  LHRQLLKRIEST-MLEIDPVAIMP-YINTCLIERECDEILQVCEYRSKAAGITKLIECLcrSDKENWPKSL 169
           568888888444.4569*******.*******************************************976 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MTAEEKQNLR FYRRYIERSL NPVYILSNMT EWLSDEMEER VRKEEEKGVT AAAALFLDAV 60
LLLEAEGWFR GFQDALAAAG YTGLAEAIEN WDFGKLEKLE LHRQLLKRIE STMLEIDPVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCGG AGGAGAAGCA GAACTTGCGG TTCTACAGGC GCTACATAGA GAGGAGCCTA 60
AACCCCGTGT ACATCCTCAG CAACATGACG GAATGGCTGT CCGATGGTGA GAGCCGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	52.33	0.00e+00	909.00
IUUC-Apl-003966	Anas platyrhynchos	76.69	0.00e+00	1319.00
IUUC-Aca-004499	Anolis carolinensis	49.08	0.00e+00	832.00
IUUC-Ame-011950	Astyanax mexicanus	41.21	0.00e+00	650.00
IUUC-Bta-012489	Bos taurus	52.33	0.00e+00	900.00
IUUC-Cel-018230	Caenorhabditis elegans	28.49	9.00e-60	225.00
IUUC-Cja-018716	Callithrix jacchus	53.22	0.00e+00	910.00
IUUC-Cfa-020269	Canis familiaris	52.55	0.00e+00	919.00
IUUC-Cpo-022507	Cavia porcellus	51.79	0.00e+00	884.00
IUUC-Csa-024209	Chlorocebus sabaeus	52.79	0.00e+00	920.00
IUUC-Cho-025104	Choloepus hoffmanni	49.68	0.00e+00	748.00
IUUC-Cin-025792	Ciona intestinalis	29.80	2.00e-74	273.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.60	6.00e-25	110.00
IUUC-Dno-028954	Dasypus novemcinctus	52.45	0.00e+00	880.00
IUUC-Eca-034039	Equus caballus	52.74	0.00e+00	912.00
IUUC-Eeu-035009	Erinaceus europaeus	50.39	0.00e+00	642.00
IUUC-Fca-036169	Felis catus	52.99	0.00e+00	937.00
IUUC-Fal-037579	Ficedula albicollis	89.17	0.00e+00	1545.00
IUUC-Ggo-045318	Gorilla gorilla	51.78	0.00e+00	858.00
IUUC-Hsa-046671	Homo sapiens	52.13	0.00e+00	899.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	50.98	0.00e+00	867.00
IUUC-Lch-050461	Latimeria chalumnae	50.74	0.00e+00	875.00
IUUC-Loc-052582	Lepisosteus oculatus	46.94	0.00e+00	779.00
IUUC-Laf-054324	Loxodonta africana	52.17	0.00e+00	890.00
IUUC-Mcc-055390	Macaca mulatta	52.46	0.00e+00	911.00
IUUC-Meu-056365	Macropus eugenii	56.40	2.00e-105	376.00
IUUC-Mvi-060497	Microbotryum violaceum	23.79	3.00e-19	91.30
IUUC-Mmr-061407	Microcebus murinus	52.07	0.00e+00	923.00
IUUC-Mmu-063939	Mus musculus	53.05	0.00e+00	910.00
IUUC-Mpu-066226	Mustela putorius furo	52.98	0.00e+00	879.00
IUUC-Mlu-068092	Myotis lucifugus	54.19	0.00e+00	918.00
IUUC-Nfi-068405	Neosartorya fischeri	24.44	4.00e-27	117.00
IUUC-Opr-070246	Ochotona princeps	46.03	6.00e-123	434.00
IUUC-Oan-072742	Ornithorhynchus anatinus	53.65	0.00e+00	813.00
IUUC-Ocu-073959	Oryctolagus cuniculus	51.75	0.00e+00	893.00
IUUC-Oga-089173	Otolemur garnettii	51.86	0.00e+00	891.00
IUUC-Oar-089369	Ovis aries	51.79	0.00e+00	873.00
IUUC-Ptr-091032	Pan troglodytes	52.13	0.00e+00	899.00
IUUC-Pan-092383	Papio anubis	52.62	0.00e+00	916.00
IUUC-Psi-093432	Pelodiscus sinensis	63.30	0.00e+00	1184.00
IUUC-Pma-094367	Petromyzon marinus	39.62	7.00e-105	374.00
IUUC-Pab-098416	Pongo abelii	53.66	0.00e+00	865.00
IUUC-Pca-101006	Procavia capensis	55.19	4.00e-126	445.00
IUUC-Pva-102966	Pteropus vampyrus	53.81	0.00e+00	926.00
IUUC-Rno-105059	Rattus norvegicus	51.41	7.00e-164	570.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	25.86	3.00e-05	45.10
IUUC-Sar-113202	Sorex araneus	48.24	0.00e+00	673.00
IUUC-Ssc-116120	Sus scrofa	51.74	0.00e+00	881.00
IUUC-Tsy-119453	Tarsius syrichta	52.66	2.00e-150	525.00
IUUC-Tre-122194	Trichoderma reesei	23.75	6.00e-19	90.10
IUUC-Ttr-128421	Tursiops truncatus	49.03	0.00e+00	701.00
IUUC-Vpa-130602	Vicugna pacos	50.92	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence