iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.00e-09	36.5	42	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplv..................lpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+++++d +++                  + C+H+fh++C+ +w       ++++ CPl+
   Q: 42   CAICRNHIMD-LCIecqanqasatseectvawGVCNHAFHFHCISRW------LKTRQVCPLD 97
           ********66.55333444444433333333488*************......********97 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM DLCIECQANQ 60
ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE WEFQKYGH 108

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG CGATGGATGT GGATACCCCC AGCGGCACCA ACAGCGGCGC GGGCAAGAAG 60
CGCTTTGAAG TTAAAAAGGT TGGGTCTCGC CAGCGCCTTC CTCAAGGAAT CTAGGGAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR024766--Znf_RING_H2

PROSITE

PS50089--ZF_RING_2

Pfam

PF12678--zf-rbx1

Gene Ontology

GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0030891--C:VCB complex
GO:0019788--F:NEDD8 transferase activity
GO:0032403--F:protein complex binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0006513--P:protein monoubiquitination
GO:0045116--P:protein neddylation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

rno:300084

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001798	Ailuropoda melanoleuca	100.00	1.00e-61	227.00
IUUC-Atr-002900	Amborella trichopoda	90.82	3.00e-51	192.00
IUUC-Apl-003762	Anas platyrhynchos	100.00	8.00e-43	164.00
IUUC-Aca-005328	Anolis carolinensis	99.07	7.00e-61	224.00
IUUC-Aly-005923	Arabidopsis lyrata	96.59	2.00e-48	183.00
IUUC-Ath-007535	Arabidopsis thaliana	94.38	9.00e-47	177.00
IUUC-Ago-007991	Ashbya gossypii	59.26	3.00e-37	145.00
IUUC-Acl-008332	Aspergillus clavatus	93.33	1.00e-48	184.00
IUUC-Afl-008537	Aspergillus flavus	94.19	2.00e-46	177.00
IUUC-Afu-008985	Aspergillus fumigatus	93.33	9.00e-49	184.00
IUUC-Ani-009342	Aspergillus nidulans	91.40	2.00e-49	187.00
IUUC-Ang-009778	Aspergillus niger	94.19	2.00e-46	177.00
IUUC-Aor-009918	Aspergillus oryzae	94.19	2.00e-46	177.00
IUUC-Ame-010814	Astyanax mexicanus	100.00	1.00e-29	120.00
IUUC-Bgr-012224	Blumeria graminis	93.33	5.00e-49	185.00
IUUC-Bta-012426	Bos taurus	100.00	1.00e-61	227.00
IUUC-Bci-013839	Botrytis cinerea	97.70	2.00e-48	183.00
IUUC-Bdi-014575	Brachypodium distachyon	95.60	2.00e-49	187.00
IUUC-Bol-015671	Brassica oleracea	97.75	2.00e-49	187.00
IUUC-Bra-017034	Brassica rapa	97.75	2.00e-49	187.00
IUUC-Cel-018195	Caenorhabditis elegans	79.28	2.00e-47	179.00
IUUC-Cja-018788	Callithrix jacchus	100.00	2.00e-59	219.00
IUUC-Cpo-021365	Cavia porcellus	100.00	1.00e-61	227.00
IUUC-Cre-022904	Chlamydomonas reinhardtii	54.64	2.00e-26	110.00
IUUC-Csa-024198	Chlorocebus sabaeus	100.00	1.00e-61	227.00
IUUC-Cho-024344	Choloepus hoffmanni	100.00	2.00e-29	119.00
IUUC-Cin-025449	Ciona intestinalis	92.23	5.00e-53	198.00
IUUC-Cgl-026522	Colletotrichum gloeosporioides	90.62	3.00e-50	189.00
IUUC-Cne-027067	Cryptococcus neoformans	69.57	2.00e-34	137.00
IUUC-Cme-027268	Cyanidioschyzon merolae	62.62	6.00e-37	145.00
IUUC-Dre-027434	Danio rerio	98.15	2.00e-60	223.00
IUUC-Dno-029252	Dasypus novemcinctus	99.05	1.00e-58	217.00
IUUC-Dor-030861	Dipodomys ordii	76.92	6.00e-42	161.00
IUUC-Dse-031355	Dothistroma septosporum	93.41	3.00e-49	186.00
IUUC-Dme-031585	Drosophila melanogaster	91.09	9.00e-52	194.00
IUUC-Ete-032747	Echinops telfairi	58.33	4.00e-26	109.00
IUUC-Eca-033758	Equus caballus	100.00	1.00e-61	227.00
IUUC-Fca-035586	Felis catus	100.00	1.00e-61	227.00
IUUC-Fal-037097	Ficedula albicollis	98.77	1.00e-44	170.00
IUUC-Fox-037881	Fusarium oxysporum	95.06	2.00e-43	166.00
IUUC-Fso-038373	Fusarium solani	87.63	3.00e-49	186.00
IUUC-Gmo-039457	Gadus morhua	99.04	4.00e-58	215.00
IUUC-Ggr-039970	Gaeumannomyces graminis	95.40	4.00e-47	179.00
IUUC-Gga-040328	Gallus gallus	100.00	1.00e-61	227.00
IUUC-Gac-041578	Gasterosteus aculeatus	98.15	2.00e-60	223.00
IUUC-Gma-042692	Glycine max	97.73	6.00e-49	185.00
IUUC-Ggo-045249	Gorilla gorilla	75.00	6.00e-41	157.00
IUUC-Hsa-046279	Homo sapiens	100.00	1.00e-61	227.00
IUUC-Hvu-047597	Hordeum vulgare	97.75	3.00e-49	186.00
IUUC-Itr-048174	Ictidomys tridecemlineatus	100.00	1.00e-61	227.00
IUUC-Kpa-049330	Komagataella pastoris	64.29	5.00e-37	145.00
IUUC-Lch-049667	Latimeria chalumnae	97.22	5.00e-60	221.00
IUUC-Lma-053052	Leptosphaeria maculans	97.75	4.00e-49	186.00
IUUC-Laf-053827	Loxodonta africana	97.22	1.00e-59	220.00
IUUC-Mcc-055208	Macaca mulatta	100.00	1.00e-61	227.00
IUUC-Meu-056143	Macropus eugenii	100.00	8.00e-46	174.00
IUUC-Mor-057158	Magnaporthe oryzae	96.55	1.00e-47	181.00
IUUC-Mpo-057409	Magnaporthe poae	95.40	4.00e-47	179.00
IUUC-Mtr-058375	Medicago truncatula	78.63	3.00e-50	189.00
IUUC-Mla-059071	Melampsora laricipopulina	72.00	4.00e-47	179.00
IUUC-Mga-059797	Meleagris gallopavo	100.00	1.00e-61	227.00
IUUC-Mvi-060401	Microbotryum violaceum	76.92	8.00e-49	185.00
IUUC-Mmr-061077	Microcebus murinus	100.00	1.00e-61	227.00
IUUC-Mdo-062218	Monodelphis domestica	100.00	1.00e-61	227.00
IUUC-Mmu-064224	Mus musculus	100.00	1.00e-61	227.00
IUUC-Mac-064505	Musa acuminata	97.73	1.00e-48	184.00
IUUC-Mpu-066572	Mustela putorius furo	100.00	1.00e-61	227.00
IUUC-Mlu-067821	Myotis lucifugus	100.00	1.00e-61	227.00
IUUC-Nfi-068412	Neosartorya fischeri	93.33	1.00e-48	184.00
IUUC-Nle-069309	Nomascus leucogenys	100.00	1.00e-61	227.00
IUUC-Opr-070307	Ochotona princeps	100.00	1.00e-61	227.00
IUUC-Ont-071677	Oreochromis niloticus	98.15	7.00e-59	218.00
IUUC-Oan-072926	Ornithorhynchus anatinus	100.00	2.00e-44	169.00
IUUC-Oba-075405	Oryza barthii	97.75	2.00e-49	186.00
IUUC-Obr-076843	Oryza brachyantha	97.75	1.00e-49	188.00
IUUC-Ogl-077608	Oryza glaberrima	97.75	2.00e-49	186.00
IUUC-Ogu-078316	Oryza glumaepatula	97.75	2.00e-49	186.00
IUUC-Oin-079918	Oryza indica	65.38	7.00e-43	166.00
IUUC-Olo-080968	Oryza longistaminata	96.23	2.00e-26	109.00
IUUC-Ome-081246	Oryza meridionalis	96.59	1.00e-48	184.00
IUUC-Oni-082133	Oryza nivara	96.51	3.00e-47	179.00
IUUC-Opu-084035	Oryza punctata	90.00	1.00e-50	190.00
IUUC-Oru-084941	Oryza rufipogon	97.75	2.00e-49	186.00
IUUC-Osa-085800	Oryza sativa	97.75	2.00e-49	186.00
IUUC-Ola-087352	Oryzias latipes	97.22	4.00e-60	222.00
IUUC-Olu-087676	Ostreococcus lucimarinus	53.49	1.00e-25	107.00
IUUC-Oga-088880	Otolemur garnettii	100.00	1.00e-61	227.00
IUUC-Oar-089286	Ovis aries	100.00	1.00e-61	227.00
IUUC-Ptr-091402	Pan troglodytes	100.00	1.00e-61	227.00
IUUC-Pan-091687	Papio anubis	97.22	3.00e-59	219.00
IUUC-Psi-093640	Pelodiscus sinensis	97.22	9.00e-60	221.00
IUUC-Pma-094723	Petromyzon marinus	98.80	5.00e-46	174.00
IUUC-Pno-094822	Phaeosphaeria nodorum	90.72	2.00e-50	190.00
IUUC-Ppa-095730	Physcomitrella patens	96.63	5.00e-49	185.00
IUUC-Pfo-096055	Poecilia formosa	99.07	6.00e-61	224.00
IUUC-Pab-098577	Pongo abelii	100.00	1.00e-61	227.00
IUUC-Pop-099697	Populus trichocarpa	82.73	1.00e-50	191.00
IUUC-Pca-100719	Procavia capensis	100.00	1.00e-61	227.00
IUUC-Ppe-101429	Prunus persica	83.33	1.00e-51	194.00
IUUC-Pva-102885	Pteropus vampyrus	74.07	2.00e-41	160.00
IUUC-Pgr-103470	Puccinia graminis	80.36	6.00e-50	188.00
IUUC-Ptt-103909	Puccinia triticina	74.07	3.00e-30	123.00
IUUC-Pte-104144	Pyrenophora teres	92.55	2.00e-46	176.00
IUUC-Pyt-104533	Pyrenophora triticirepentis	91.67	1.00e-49	187.00
IUUC-Sce-106407	Saccharomyces cerevisiae	66.29	2.00e-34	137.00
IUUC-Sha-107549	Sarcophilus harrisii	100.00	1.00e-61	227.00
IUUC-Sja-108003	Schizosaccharomyces japonicus	82.24	4.00e-48	182.00
IUUC-Spo-108091	Schizosaccharomyces pombe	74.07	1.00e-44	171.00
IUUC-Ssl-108634	Sclerotinia sclerotiorum	97.70	2.00e-48	183.00
IUUC-Smo-109681	Selaginella moellendorffii	97.73	9.00e-49	184.00
IUUC-Sit-110419	Setaria italica	95.51	2.00e-48	183.00
IUUC-Sly-110933	Solanum lycopersicum	85.19	5.00e-51	192.00
IUUC-Stu-112567	Solanum tuberosum	88.89	1.00e-50	191.00
IUUC-Sar-113409	Sorex araneus	75.00	9.00e-42	161.00
IUUC-Sbi-113799	Sorghum bicolor	93.62	1.00e-49	187.00
IUUC-Sre-115142	Sporisorium reilianum	81.90	4.00e-48	182.00
IUUC-Tgu-116923	Taeniopygia guttata	98.73	5.00e-43	164.00
IUUC-Tru-117710	Takifugu rubripes	93.52	7.00e-57	211.00
IUUC-Tsy-119641	Tarsius syrichta	100.00	6.00e-26	108.00
IUUC-Tni-119934	Tetraodon nigroviridis	97.22	2.00e-60	223.00
IUUC-Tca-121820	Theobroma cacao	96.63	5.00e-49	185.00
IUUC-Tre-122212	Trichoderma reesei	95.06	7.00e-44	168.00
IUUC-Tvi-122357	Trichoderma virens	86.67	5.00e-50	189.00
IUUC-Tae-125834	Triticum aestivum	91.67	7.00e-50	188.00
IUUC-Tur-125958	Triticum urartu	97.73	1.00e-48	183.00
IUUC-Tme-126940	Tuber melanosporum	83.17	3.00e-48	182.00
IUUC-Tbe-127918	Tupaia belangeri	100.00	8.00e-46	174.00
IUUC-Ttr-128306	Tursiops truncatus	100.00	8.00e-46	174.00
IUUC-Uma-129482	Ustilago maydis	77.14	6.00e-46	174.00
IUUC-Vda-129917	Verticillium dahliae	86.92	5.00e-52	195.00
IUUC-Vpa-130142	Vicugna pacos	97.12	2.00e-55	206.00
IUUC-Vvi-130957	Vitis vinifera	97.73	5.00e-49	185.00
IUUC-Xma-133061	Xiphophorus maculatus	99.07	6.00e-61	224.00
IUUC-Yli-134542	Yarrowia lipolytica	59.65	3.00e-37	146.00
IUUC-Zma-135160	Zea mays	97.75	2.00e-49	186.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence