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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045674
Ensembl Protein ID ENSP00000487444.1
UniProt Accession A0A0D9SGF6; A0A0D9SGF6_HUMAN
Genbank Protein ID ENSP00000487444
Protein Name Spectrin alpha chain, non-erythrocytic 1
Genbank Nucleotide ID AL356481
Gene Name SPTAN1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000197694.14 ENST00000372731.8 ENSP00000361816.4
ENSG00000197694.14 ENST00000630804.2 ENSP00000486308.1
ENSG00000197694.14 ENST00000627441.2 ENSP00000486547.1
ENSG00000197694.14 ENST00000372739.5 ENSP00000361824.3
ENSG00000197694.14 ENST00000358161.9 ENSP00000350882.6
ENSG00000197694.14 ENST00000630866.1 ENSP00000487444.1
ENSG00000197694.14 ENST00000635806.1 ENSP00000489647.1
ENSG00000197694.14 ENST00000637820.1 ENSP00000490179.1
ENSG00000197694.14 ENST00000637903.1 ENSP00000490332.1
ENSG00000197694.14 ENST00000637032.1 ENSP00000490109.1
ENSG00000197694.14 ENST00000630981.1 ENSP00000486605.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBasecircRNADbCircNet
miRTarBasemicroRNATRANSFACmiRWalk
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
HINTInWeb_IM
Disease-associated Variation
ClinVarOMIM
Post-translational Modifications (PTMs)
PHOSIDABioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 5.60e-10 40.7 969 1025
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ke+v +lydy+ ++  e t+kkGd+++++  ++++++W+k   e + ++G++P+ +v+kl+
   Q: 969  KELVLALYDYQEKSPREVTMKKGDILTLL--NSTNKDWWKV--EVNDRQGFVPAAYVKKLD 1025
           68899************************..8999****88..9**************996 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MDPSGVKVLE TAEDIQERRQ QVLDRYHRFK ELSTLRRQKL EDSYRFQFFQ RDAEELEKWI 60
QEKLQIASDE NYKDPTNLQG KLQKHQAFEA EVQANSGAIV KLDETGNLMI SEGHFASETI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045674|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TATAAAAGAG GCGGGGCGCG CGCGTCGCCG CCACTACCCG CTGCGGAGTG AACGGTGTGG 60
AGCGGAGGCC GCGGAGGCTC CTCGGTCCTT CAGCACCCCT CGGCCCGACG CACCCACGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045674|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR011992--EF-hand-dom_pair
IPR014837--EF-hand_Ca_insen
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR013315--Spectrin_alpha_SH3
IPR002017--Spectrin_repeat
PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50002--SH3
Pfam

PF13499--EF-hand_7
PF08726--EFhand_Ca_insen
PF00018--SH3_1
PF00435--Spectrin
PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA
SMART

SM00054--EFh
SM00326--SH3
SM00150--SPEC
Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0015630--C:microtubule cytoskeleton
GO:0005509--F:calcium ion binding
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001430 Ailuropoda melanoleuca 97.16 0.00e+00 4801.00
IUUC-Apl-003692 Anas platyrhynchos 96.12 0.00e+00 4711.00
IUUC-Ame-010974 Astyanax mexicanus 90.88 0.00e+00 4511.00
IUUC-Bta-013123 Bos taurus 98.08 0.00e+00 4835.00
IUUC-Cja-019004 Callithrix jacchus 98.48 0.00e+00 4850.00
IUUC-Cfa-021120 Canis familiaris 97.64 0.00e+00 4823.00
IUUC-Cpo-022439 Cavia porcellus 96.38 0.00e+00 4644.00
IUUC-Csa-024191 Chlorocebus sabaeus 98.96 0.00e+00 4874.00
IUUC-Cho-024438 Choloepus hoffmanni 97.97 0.00e+00 2137.00
IUUC-Dre-028311 Danio rerio 88.47 0.00e+00 4457.00
IUUC-Dno-029578 Dasypus novemcinctus 98.12 0.00e+00 4843.00
IUUC-Dor-030109 Dipodomys ordii 98.15 0.00e+00 1183.00
IUUC-Dme-032108 Drosophila melanogaster 63.16 0.00e+00 3112.00
IUUC-Fca-036305 Felis catus 97.28 0.00e+00 4806.00
IUUC-Fal-036784 Ficedula albicollis 96.88 0.00e+00 4865.00
IUUC-Gmo-039575 Gadus morhua 88.41 0.00e+00 4368.00
IUUC-Gga-041118 Gallus gallus 95.96 0.00e+00 4758.00
IUUC-Gac-042549 Gasterosteus aculeatus 89.05 0.00e+00 4405.00
IUUC-Ggo-044946 Gorilla gorilla 99.04 0.00e+00 4877.00
IUUC-Lch-050567 Latimeria chalumnae 92.01 0.00e+00 4556.00
IUUC-Loc-052651 Lepisosteus oculatus 90.89 0.00e+00 4558.00
IUUC-Laf-053912 Loxodonta africana 98.04 0.00e+00 4856.00
IUUC-Mcc-054610 Macaca mulatta 99.80 0.00e+00 4936.00
IUUC-Meu-055913 Macropus eugenii 86.09 0.00e+00 1709.00
IUUC-Mga-059315 Meleagris gallopavo 96.00 0.00e+00 4779.00
IUUC-Mmr-061183 Microcebus murinus 99.24 0.00e+00 4909.00
IUUC-Mdo-062180 Monodelphis domestica 96.31 0.00e+00 4364.00
IUUC-Mmu-063687 Mus musculus 98.40 0.00e+00 4918.00
IUUC-Mpu-066425 Mustela putorius furo 97.28 0.00e+00 4808.00
IUUC-Mlu-067943 Myotis lucifugus 98.29 0.00e+00 4900.00
IUUC-Nle-069271 Nomascus leucogenys 99.05 0.00e+00 2419.00
IUUC-Opr-070237 Ochotona princeps 94.68 0.00e+00 4665.00
IUUC-Ont-072393 Oreochromis niloticus 89.05 0.00e+00 4425.00
IUUC-Oan-073113 Ornithorhynchus anatinus 96.04 0.00e+00 4727.00
IUUC-Ocu-074516 Oryctolagus cuniculus 97.40 0.00e+00 4855.00
IUUC-Ola-086839 Oryzias latipes 88.82 0.00e+00 4398.00
IUUC-Oga-089094 Otolemur garnettii 86.90 0.00e+00 4218.00
IUUC-Oar-089374 Ovis aries 98.89 0.00e+00 4393.00
IUUC-Ptr-090495 Pan troglodytes 99.00 0.00e+00 4873.00
IUUC-Pan-091959 Papio anubis 98.96 0.00e+00 4873.00
IUUC-Pab-097592 Pongo abelii 99.80 0.00e+00 4984.00
IUUC-Pca-100304 Procavia capensis 94.77 0.00e+00 2825.00
IUUC-Pva-102161 Pteropus vampyrus 97.41 0.00e+00 4374.00
IUUC-Rno-105394 Rattus norvegicus 98.60 0.00e+00 4883.00
IUUC-Sha-107395 Sarcophilus harrisii 97.36 0.00e+00 4806.00
IUUC-Ssc-116146 Sus scrofa 96.72 0.00e+00 4764.00
IUUC-Tgu-117103 Taeniopygia guttata 94.60 0.00e+00 4717.00
IUUC-Tru-118183 Takifugu rubripes 88.28 0.00e+00 3886.00
IUUC-Tsy-118789 Tarsius syrichta 83.04 0.00e+00 1174.00
IUUC-Tni-120816 Tetraodon nigroviridis 87.45 0.00e+00 4348.00
IUUC-Ttr-128853 Tursiops truncatus 92.96 0.00e+00 4458.00
IUUC-Vpa-130628 Vicugna pacos 97.33 0.00e+00 2844.00
IUUC-Xtr-132872 Xenopus tropicalis 90.56 0.00e+00 4454.00
Created Date 25-Jun-2017

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