iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	55.90	8.00e-143	506.00	IUUC-Hsa-046670
UBD/Alpha-Helix/UBA	56.35	7.00e-144	509.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MTSTSAVDGG LGSETAWLED LLREVQLEQF LDRIRDDLQV TRLAHFDYVL PDDLERCGLG 60
KPAIRRLMEA VRKKKAHQWR KNILSKLIGG GKQPSSKKQS SAARESSQGN GTQLTCLIHE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTGCATCA GCTGCTTGAA AAAATACCAA AAGTGTTTGG CCGTCGCGCA TTTTCAATTG 60
CAAATTAAGC GCAGCTAACT GCGATTAACG ACGATGTTTC CGCATTAGAA AGAAAATCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50030--UBA

Pfam

PF07714--Pkinase_Tyr

PRINTS

PR00109--TYRKINASE

SMART

SM00219--TyrKc

Gene Ontology

GO:0071944--C:cell periphery
GO:0030136--C:clathrin-coated vesicle
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0042169--F:SH2 domain binding
GO:0016477--P:cell migration
GO:0034613--P:cellular protein localization
GO:0007391--P:dorsal closure
GO:0045087--P:innate immune response
GO:0043066--P:negative regulation of apoptotic process
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0018108--P:peptidyl-tyrosine phosphorylation
GO:0035332--P:positive regulation of hippo signaling
GO:0006468--P:protein phosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007286--P:spermatid development
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

dme:Dmel_CG14992

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	56.44	1.00e-133	470.00
IUUC-Aca-004315	Anolis carolinensis	69.12	1.00e-56	211.00
IUUC-Ame-011350	Astyanax mexicanus	54.64	5.00e-141	494.00
IUUC-Bta-012325	Bos taurus	56.79	6.00e-142	497.00
IUUC-Cel-018130	Caenorhabditis elegans	38.26	2.00e-79	290.00
IUUC-Cja-019545	Callithrix jacchus	50.43	1.00e-120	426.00
IUUC-Cfa-020706	Canis familiaris	56.57	2.00e-141	495.00
IUUC-Cpo-022032	Cavia porcellus	56.79	1.00e-141	496.00
IUUC-Csa-023936	Chlorocebus sabaeus	56.35	2.00e-140	492.00
IUUC-Csv-026328	Ciona savignyi	51.60	2.00e-130	458.00
IUUC-Dre-028714	Danio rerio	55.68	7.00e-143	501.00
IUUC-Dno-029525	Dasypus novemcinctus	56.35	1.00e-141	496.00
IUUC-Ete-032225	Echinops telfairi	52.88	3.00e-117	415.00
IUUC-Fca-035664	Felis catus	56.35	2.00e-141	496.00
IUUC-Gmo-039543	Gadus morhua	51.57	5.00e-132	464.00
IUUC-Gga-040241	Gallus gallus	53.69	6.00e-137	481.00
IUUC-Gac-041457	Gasterosteus aculeatus	52.77	3.00e-134	472.00
IUUC-Ggo-045333	Gorilla gorilla	56.35	2.00e-140	492.00
IUUC-Hsa-046670	Homo sapiens	56.35	2.00e-140	492.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	56.57	1.00e-141	496.00
IUUC-Lch-049670	Latimeria chalumnae	58.88	1.00e-138	486.00
IUUC-Loc-052870	Lepisosteus oculatus	58.60	2.00e-146	513.00
IUUC-Laf-053782	Loxodonta africana	53.45	1.00e-132	466.00
IUUC-Mcc-055874	Macaca mulatta	56.35	3.00e-140	492.00
IUUC-Mga-059717	Meleagris gallopavo	56.18	2.00e-145	509.00
IUUC-Mdo-062270	Monodelphis domestica	55.90	1.00e-140	493.00
IUUC-Mmu-063861	Mus musculus	57.24	4.00e-143	501.00
IUUC-Mpu-066127	Mustela putorius furo	56.57	5.00e-135	474.00
IUUC-Mlu-067937	Myotis lucifugus	56.35	1.00e-141	496.00
IUUC-Nle-069298	Nomascus leucogenys	59.27	2.00e-107	382.00
IUUC-Ont-072437	Oreochromis niloticus	53.54	1.00e-136	480.00
IUUC-Ola-087023	Oryzias latipes	53.42	2.00e-135	475.00
IUUC-Psi-093401	Pelodiscus sinensis	51.03	9.00e-120	423.00
IUUC-Pfo-097018	Poecilia formosa	54.52	3.00e-140	492.00
IUUC-Rno-105586	Rattus norvegicus	57.24	1.00e-143	503.00
IUUC-Sha-106868	Sarcophilus harrisii	55.61	6.00e-139	487.00
IUUC-Ssc-116250	Sus scrofa	56.22	3.00e-136	479.00
IUUC-Tgu-116592	Taeniopygia guttata	55.83	1.00e-143	503.00
IUUC-Tru-117907	Takifugu rubripes	49.01	4.00e-122	432.00
IUUC-Tsy-119087	Tarsius syrichta	50.90	3.00e-108	385.00
IUUC-Tni-120826	Tetraodon nigroviridis	55.36	5.00e-139	488.00
IUUC-Xtr-132069	Xenopus tropicalis	55.84	4.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence