iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002307

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01010986

Gene Name

SPOP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012318.1	ENSAMET00000013533.1	ENSAMEP00000012989.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.70e-33	113.0	201	267
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-08	31.7	300	327

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++l+v+g+ef+ahk++Laa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 201  TDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNL 267
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfil 28
           +eN+++il +Adl+++++Lk +a+dfi+
   Q: 300  VENAAEILILADLHSADQLKTQAVDFIN 327
           79*************************7 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MSRVPSPPPP AEMSSGPVAE SWCYTQQIKV VKFSYMWTIN NFSFCREEMG EVIKSSTFSS 60
GANDKLKWCL RVNPKGLDEE SKDYLSLYLL LVSCPKSEVR AKFKFSILNA KGEETKAMES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGGG TTCCAAGTCC TCCACCTCCG GCAGAAATGT CGAGTGGCCC CGTAGCTGAG 60
AGCTGGTGCT ACACACAGGT AAGTTCATGT TTTCGCTCTG TAAATTGTGT ATCTTGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016607--C:nuclear speck
GO:0042593--P:glucose homeostasis
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676--P:positive regulation of type B pancreatic cell apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000920	Aegilops tauschii	30.89	1.00e-38	153.00
IUUC-Apl-003488	Anas platyrhynchos	94.91	0.00e+00	699.00
IUUC-Aca-005010	Anolis carolinensis	94.66	0.00e+00	697.00
IUUC-Aly-005426	Arabidopsis lyrata	31.56	2.00e-39	156.00
IUUC-Ath-007670	Arabidopsis thaliana	28.27	9.00e-36	144.00
IUUC-Afl-008594	Aspergillus flavus	38.46	1.00e-03	36.20
IUUC-Afu-008999	Aspergillus fumigatus	25.49	4.00e-05	41.60
IUUC-Aor-009945	Aspergillus oryzae	38.46	3.00e-04	36.60
IUUC-Bgr-012157	Blumeria graminis	35.00	1.00e-04	40.00
IUUC-Bta-012931	Bos taurus	95.17	0.00e+00	699.00
IUUC-Bdi-014743	Brachypodium distachyon	33.65	9.00e-42	164.00
IUUC-Bol-015794	Brassica oleracea	31.88	5.00e-40	158.00
IUUC-Cel-018671	Caenorhabditis elegans	62.50	1.00e-130	459.00
IUUC-Cja-019981	Callithrix jacchus	95.42	0.00e+00	706.00
IUUC-Cfa-020115	Canis familiaris	95.17	0.00e+00	699.00
IUUC-Cpo-021366	Cavia porcellus	95.17	0.00e+00	705.00
IUUC-Cre-022954	Chlamydomonas reinhardtii	30.99	2.00e-06	48.50
IUUC-Cin-025636	Ciona intestinalis	72.82	1.00e-154	538.00
IUUC-Csv-026167	Ciona savignyi	68.37	2.00e-151	528.00
IUUC-Cgl-026729	Colletotrichum gloeosporioides	30.30	7.00e-06	45.10
IUUC-Dre-027603	Danio rerio	92.62	0.00e+00	681.00
IUUC-Dno-029006	Dasypus novemcinctus	89.92	0.00e+00	641.00
IUUC-Dor-030503	Dipodomys ordii	95.12	0.00e+00	693.00
IUUC-Dme-032218	Drosophila melanogaster	75.83	2.00e-155	543.00
IUUC-Ete-032328	Echinops telfairi	94.54	0.00e+00	643.00
IUUC-Eca-033238	Equus caballus	95.17	0.00e+00	699.00
IUUC-Eeu-034739	Erinaceus europaeus	79.90	2.00e-171	594.00
IUUC-Fca-035435	Felis catus	95.17	0.00e+00	699.00
IUUC-Gmo-038600	Gadus morhua	91.35	0.00e+00	677.00
IUUC-Ggr-039811	Gaeumannomyces graminis	32.88	4.00e-08	52.40
IUUC-Gga-040441	Gallus gallus	94.91	0.00e+00	699.00
IUUC-Gac-041911	Gasterosteus aculeatus	92.11	0.00e+00	681.00
IUUC-Gma-043988	Glycine max	32.91	1.00e-39	157.00
IUUC-Hsa-045835	Homo sapiens	95.17	0.00e+00	699.00
IUUC-Hvu-047439	Hordeum vulgare	32.10	3.00e-36	145.00
IUUC-Itr-048058	Ictidomys tridecemlineatus	93.04	0.00e+00	665.00
IUUC-Lch-050241	Latimeria chalumnae	93.89	0.00e+00	694.00
IUUC-Loc-052374	Lepisosteus oculatus	94.15	0.00e+00	694.00
IUUC-Laf-054192	Loxodonta africana	95.42	0.00e+00	706.00
IUUC-Mcc-055322	Macaca mulatta	95.17	0.00e+00	699.00
IUUC-Meu-056330	Macropus eugenii	88.30	0.00e+00	645.00
IUUC-Mor-057237	Magnaporthe oryzae	29.41	8.00e-08	50.80
IUUC-Mpo-057466	Magnaporthe poae	28.36	5.00e-08	51.20
IUUC-Mtr-058558	Medicago truncatula	31.65	3.00e-37	149.00
IUUC-Mga-059579	Meleagris gallopavo	95.17	0.00e+00	702.00
IUUC-Mmr-061309	Microcebus murinus	95.17	0.00e+00	699.00
IUUC-Mmu-064227	Mus musculus	95.17	0.00e+00	699.00
IUUC-Mpu-065693	Mustela putorius furo	95.17	0.00e+00	699.00
IUUC-Mlu-067827	Myotis lucifugus	95.17	0.00e+00	705.00
IUUC-Nle-069393	Nomascus leucogenys	95.17	0.00e+00	699.00
IUUC-Opr-070490	Ochotona princeps	93.38	0.00e+00	684.00
IUUC-Ont-071726	Oreochromis niloticus	92.37	0.00e+00	682.00
IUUC-Ocu-074932	Oryctolagus cuniculus	95.17	0.00e+00	699.00
IUUC-Ogu-078752	Oryza glumaepatula	32.77	1.00e-36	148.00
IUUC-Olo-080833	Oryza longistaminata	31.94	5.00e-37	148.00
IUUC-Ome-081184	Oryza meridionalis	31.49	6.00e-37	149.00
IUUC-Opu-083303	Oryza punctata	31.27	2.00e-27	117.00
IUUC-Ola-086989	Oryzias latipes	92.13	0.00e+00	678.00
IUUC-Oga-089107	Otolemur garnettii	95.17	0.00e+00	699.00
IUUC-Oar-089943	Ovis aries	95.42	0.00e+00	706.00
IUUC-Ptr-091201	Pan troglodytes	95.17	0.00e+00	699.00
IUUC-Pan-092504	Papio anubis	95.17	0.00e+00	699.00
IUUC-Psi-093063	Pelodiscus sinensis	94.91	0.00e+00	699.00
IUUC-Ppa-095322	Physcomitrella patens	32.09	3.00e-40	159.00
IUUC-Pfo-096411	Poecilia formosa	92.37	0.00e+00	682.00
IUUC-Pab-098640	Pongo abelii	95.17	0.00e+00	699.00
IUUC-Pop-099477	Populus trichocarpa	32.40	3.00e-40	159.00
IUUC-Pca-100243	Procavia capensis	99.49	1.00e-108	385.00
IUUC-Pva-102296	Pteropus vampyrus	88.55	0.00e+00	633.00
IUUC-Pyt-104526	Pyrenophora triticirepentis	23.53	1.00e-06	47.40
IUUC-Rno-105399	Rattus norvegicus	95.17	0.00e+00	699.00
IUUC-Sha-106700	Sarcophilus harrisii	94.66	0.00e+00	697.00
IUUC-Spo-108262	Schizosaccharomyces pombe	36.84	8.90e-02	32.30
IUUC-Ssl-108548	Sclerotinia sclerotiorum	28.77	1.00e-06	47.00
IUUC-Smo-108684	Selaginella moellendorffii	31.35	6.00e-31	128.00
IUUC-Sit-109872	Setaria italica	32.48	5.00e-40	158.00
IUUC-Sly-110931	Solanum lycopersicum	30.48	8.00e-41	160.00
IUUC-Stu-112216	Solanum tuberosum	31.05	1.00e-40	160.00
IUUC-Sar-113489	Sorex araneus	95.17	0.00e+00	699.00
IUUC-Sbi-114704	Sorghum bicolor	35.14	2.00e-40	159.00
IUUC-Tru-117832	Takifugu rubripes	91.60	0.00e+00	677.00
IUUC-Tsy-118969	Tarsius syrichta	90.33	0.00e+00	655.00
IUUC-Tni-120221	Tetraodon nigroviridis	91.60	0.00e+00	677.00
IUUC-Tca-121715	Theobroma cacao	31.64	1.00e-42	167.00
IUUC-Tae-124643	Triticum aestivum	37.00	1.00e-39	157.00
IUUC-Tur-126285	Triticum urartu	37.00	6.00e-40	157.00
IUUC-Tbe-127298	Tupaia belangeri	94.66	0.00e+00	687.00
IUUC-Ttr-128952	Tursiops truncatus	94.91	0.00e+00	698.00
IUUC-Vda-129835	Verticillium dahliae	42.00	7.00e-07	48.90
IUUC-Vpa-130735	Vicugna pacos	89.57	0.00e+00	632.00
IUUC-Vvi-130854	Vitis vinifera	31.65	5.00e-32	131.00
IUUC-Xtr-132806	Xenopus tropicalis	93.42	0.00e+00	687.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence