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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063382
UUCD1 version UUC-MuM-00829
Ensembl Protein ID ENSMUSP00000023219.7
UniProt Accession Q9QXW0; Q9JJD7; FBXL6_MOUSE
Genbank Protein ID AAF22828.1; BAA95055.1; AAH54377.1
Protein Name F-box/LRR-repeat protein 6; F-box and leucine-rich repeat protein 6; F-box protein FBL6
Genbank Nucleotide ID AF176522; AB041571; BC054377
Gene Name Fbxl6; Fbl6; MNCb-1275
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022559.7 ENSMUST00000023219.7 ENSMUSP00000023219.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/SCF/F-box 4.00e-42 144.9 10 153
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/SCF/F-box
   S: 1    rrraraaprp....rsaedwwwdrlaprgsgyhllqsdsmllvlsepgparpraqrrasrrtprqpprgpsaaakpkaglrseaaaapa 85
           rrr r++ rp    rsaedwwwdrlaprgsgyhllq+dsmllvl +  p r ra rra rr+pr   rgp+a akp++           
   Q: 10   RRRVRSSKRPdargRSAEDWWWDRLAPRGSGYHLLQADSMLLVLPDLEPPRARAHRRARRRAPRSLARGPTAVAKPRT----------- 87
           788887776655559************************************************************986........... PP
   S: 86   papaptptpeegpdaglldrlpeeilveilkll...dkee..llraarvcrrwqelasqkalwktvt 147
             p p p+ ++g d+g++dr+p+e+lv+i++ll   ++++  l+raarvcr+w+e++s+++lw+tvt
   Q: 88   -KPRPEPSLDQGLDSGWGDRIPLEVLVHIFGLLvaaHGPMpfLGRAARVCRHWHEATSHPSLWHTVT 153
           .57788999************************999555566***********************98 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Protein Sequence
(Fasta)
MAPVASRRVR RRVRSSKRPD ARGRSAEDWW WDRLAPRGSG YHLLQADSML LVLPDLEPPR 60
ARAHRRARRR APRSLARGPT AVAKPRTKPR PEPSLDQGLD SGWGDRIPLE VLVHIFGLLV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063382|E3,F-box|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTCCGCTTT TAGTTCAGCT CCCGGGGGCT ATGGCTCCCG TGGCCTCTAG GCGAGTTAGA 60
CGTCGAGTTC GAAGCTCCAA GCGGCCCGAT GCGCGGGGCC GCTCGGCGGA GGACTGGTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063382|E3,F-box|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
Pfam

PF12937--F-box-like
SMART

SM00367--LRR_CC
KEGG mmu:30840
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002047 Ailuropoda melanoleuca 76.15 0.00e+00 703.00
IUUC-Aca-004785 Anolis carolinensis 48.45 1.00e-49 189.00
IUUC-Ani-009209 Aspergillus nidulans 32.88 1.00e-04 42.00
IUUC-Ame-011690 Astyanax mexicanus 38.62 9.00e-37 147.00
IUUC-Bta-012781 Bos taurus 78.90 0.00e+00 754.00
IUUC-Cja-018799 Callithrix jacchus 69.67 1.00e-107 383.00
IUUC-Cfa-020518 Canis familiaris 82.74 0.00e+00 645.00
IUUC-Cpo-022012 Cavia porcellus 78.12 0.00e+00 768.00
IUUC-Csa-023717 Chlorocebus sabaeus 84.62 3.00e-180 624.00
IUUC-Dre-028685 Danio rerio 42.45 1.00e-93 337.00
IUUC-Dno-029881 Dasypus novemcinctus 80.00 4.00e-108 384.00
IUUC-Dme-032069 Drosophila melanogaster 32.64 2.00e-46 181.00
IUUC-Eca-034384 Equus caballus 82.28 0.00e+00 673.00
IUUC-Eeu-034885 Erinaceus europaeus 70.39 4.00e-177 614.00
IUUC-Fca-036109 Felis catus 78.26 0.00e+00 717.00
IUUC-Gmo-039122 Gadus morhua 36.01 3.00e-67 249.00
IUUC-Gac-042048 Gasterosteus aculeatus 38.42 2.00e-92 333.00
IUUC-Ggo-045521 Gorilla gorilla 79.65 0.00e+00 736.00
IUUC-Hsa-046499 Homo sapiens 80.35 0.00e+00 784.00
IUUC-Itr-048984 Ictidomys tridecemlineatus 78.28 0.00e+00 738.00
IUUC-Loc-052284 Lepisosteus oculatus 45.39 1.00e-94 340.00
IUUC-Laf-053367 Loxodonta africana 81.22 1.00e-173 602.00
IUUC-Mcc-055865 Macaca mulatta 80.72 0.00e+00 741.00
IUUC-Meu-056048 Macropus eugenii 58.01 3.00e-113 401.00
IUUC-Mvi-060502 Microbotryum violaceum 25.54 2.00e-05 44.70
IUUC-Mmr-061506 Microcebus murinus 76.37 0.00e+00 706.00
IUUC-Mdo-062323 Monodelphis domestica 55.27 7.00e-139 487.00
IUUC-Mpu-066188 Mustela putorius furo 80.92 0.00e+00 632.00
IUUC-Nle-069437 Nomascus leucogenys 82.68 0.00e+00 658.00
IUUC-Ont-072058 Oreochromis niloticus 43.09 1.00e-81 297.00
IUUC-Oan-072773 Ornithorhynchus anatinus 46.43 1.00e-107 384.00
IUUC-Ogl-077479 Oryza glaberrima 26.16 4.00e-11 62.40
IUUC-Ogu-078215 Oryza glumaepatula 24.73 6.00e-10 58.20
IUUC-Oin-079411 Oryza indica 26.88 1.00e-11 63.90
IUUC-Ome-081759 Oryza meridionalis 27.24 2.00e-10 62.00
IUUC-Oru-084766 Oryza rufipogon 26.88 1.00e-10 62.00
IUUC-Osa-085658 Oryza sativa 26.88 1.00e-11 63.90
IUUC-Ola-086656 Oryzias latipes 39.51 2.00e-62 232.00
IUUC-Oga-088299 Otolemur garnettii 75.44 0.00e+00 703.00
IUUC-Oar-089657 Ovis aries 77.89 0.00e+00 734.00
IUUC-Ptr-090950 Pan troglodytes 79.77 0.00e+00 728.00
IUUC-Pan-092741 Papio anubis 80.91 0.00e+00 740.00
IUUC-Psi-093324 Pelodiscus sinensis 50.84 5.00e-76 277.00
IUUC-Pma-094256 Petromyzon marinus 37.33 2.00e-46 180.00
IUUC-Pfo-096992 Poecilia formosa 39.48 2.00e-82 300.00
IUUC-Pca-100265 Procavia capensis 67.21 3.00e-94 338.00
IUUC-Pva-103253 Pteropus vampyrus 80.14 9.00e-173 600.00
IUUC-Rno-106011 Rattus norvegicus 93.62 0.00e+00 903.00
IUUC-Sha-106485 Sarcophilus harrisii 56.08 2.00e-136 479.00
IUUC-Ssc-115464 Sus scrofa 75.78 0.00e+00 692.00
IUUC-Tsy-119633 Tarsius syrichta 65.03 8.00e-140 490.00
IUUC-Tni-120580 Tetraodon nigroviridis 44.54 6.00e-22 96.70
IUUC-Ttr-128827 Tursiops truncatus 81.54 0.00e+00 689.00
Created Date 25-Jun-2017

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