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Tag Content
UUCD2 ID IUUC-Dre-028186
UUCD1 version UUC-DaR-01237
Ensembl Protein ID ENSDARP00000141877.1
UniProt Accession Q6NYX6; CCNF_DANRE
Genbank Protein ID AAH66425.1
Protein Name Cyclin-F
Genbank Nucleotide ID BC066425
Gene Name ccnf
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000105046.1 ENSDART00000167177.1 ENSDARP00000141877.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 55.16 0.00e+00 691.00 IUUC-Hsa-046867
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Danio rerio
Functional Description
(View)

Functional Description


     Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during G2 phase.
 Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during G2 phase.
Protein Sequence
(Fasta)
MKAGALHCRC AKCFSLPVRK RVRKRASAVS LLSLPEELLV FVLQCLSAED LLSVRAVHSH 60
LCDIIDTNAS IWARVSFKDR WPAPDTVWLF ERAAEKGNFE AAVKLGIAYL YNEGPLLSEE 120
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Protein Fasta Sequence


>IUUC-Dre-028186|E3,F-box|Danio rerio
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Nucleotide Sequence
(Fasta)
GAATTTAGTA ACTTAGGTTA ATCAGCAAGA CTGATTATAT TAATCAAGAG TCTAAGTCTC 60
ATTTTCAGTT GACTGTGAAG CATCATTGCT GTAAGCTGAC TTTCCCTGAT CCCTCCTTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028186|E3,F-box|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0195--Cyclin
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR028857--CCNF_metazoan
IPR013763--Cyclin-like
IPR004367--Cyclin_C-dom
IPR006671--Cyclin_N
IPR001810--F-box_dom
PROSITE

PS00292--CYCLINS
PS50181--FBOX
Pfam

PF02984--Cyclin_C
PF00134--Cyclin_N
PF12937--F-box-like
SMART

SM00385--CYCLIN
SM01332--Cyclin_C
SM00256--FBOX
Gene Ontology

GO:0005814--C:centriole
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0010826--P:negative regulation of centrosome duplication
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
KEGG dre:266981
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001520 Ailuropoda melanoleuca 50.95 0.00e+00 665.00
IUUC-Apl-003215 Anas platyrhynchos 54.58 0.00e+00 781.00
IUUC-Ame-011700 Astyanax mexicanus 65.22 0.00e+00 935.00
IUUC-Bta-013230 Bos taurus 51.75 0.00e+00 686.00
IUUC-Bci-013663 Botrytis cinerea 28.17 8.80e-01 28.50
IUUC-Cja-019256 Callithrix jacchus 51.94 0.00e+00 703.00
IUUC-Cfa-020123 Canis familiaris 54.07 0.00e+00 677.00
IUUC-Cpo-021599 Cavia porcellus 57.21 0.00e+00 718.00
IUUC-Csa-023518 Chlorocebus sabaeus 52.61 6.00e-176 611.00
IUUC-Dno-029401 Dasypus novemcinctus 59.08 0.00e+00 709.00
IUUC-Dor-031087 Dipodomys ordii 53.65 0.00e+00 664.00
IUUC-Ete-032869 Echinops telfairi 66.24 2.00e-54 206.00
IUUC-Eca-033473 Equus caballus 51.00 0.00e+00 681.00
IUUC-Eeu-034533 Erinaceus europaeus 49.76 7.00e-90 325.00
IUUC-Fca-035961 Felis catus 50.38 0.00e+00 667.00
IUUC-Fal-036659 Ficedula albicollis 52.61 0.00e+00 726.00
IUUC-Gmo-039557 Gadus morhua 65.62 0.00e+00 736.00
IUUC-Gga-040389 Gallus gallus 50.80 7.00e-177 614.00
IUUC-Gac-042059 Gasterosteus aculeatus 64.27 0.00e+00 829.00
IUUC-Ggo-044497 Gorilla gorilla 56.52 0.00e+00 693.00
IUUC-Hsa-046867 Homo sapiens 56.52 0.00e+00 692.00
IUUC-Itr-047922 Ictidomys tridecemlineatus 56.22 0.00e+00 723.00
IUUC-Lch-050143 Latimeria chalumnae 56.73 0.00e+00 702.00
IUUC-Loc-052538 Lepisosteus oculatus 67.74 5.00e-49 186.00
IUUC-Laf-054481 Loxodonta africana 55.90 0.00e+00 674.00
IUUC-Mcc-055426 Macaca mulatta 57.23 0.00e+00 691.00
IUUC-Meu-056150 Macropus eugenii 51.70 0.00e+00 637.00
IUUC-Mga-059822 Meleagris gallopavo 51.48 1.00e-166 580.00
IUUC-Mmr-061785 Microcebus murinus 56.36 0.00e+00 683.00
IUUC-Mdo-062763 Monodelphis domestica 53.02 0.00e+00 752.00
IUUC-Mmu-064391 Mus musculus 56.66 0.00e+00 708.00
IUUC-Mpu-065756 Mustela putorius furo 53.36 0.00e+00 674.00
IUUC-Mlu-067607 Myotis lucifugus 51.44 0.00e+00 677.00
IUUC-Nle-069147 Nomascus leucogenys 57.98 0.00e+00 681.00
IUUC-Opr-071129 Ochotona princeps 52.36 0.00e+00 716.00
IUUC-Ont-072031 Oreochromis niloticus 65.16 0.00e+00 880.00
IUUC-Oan-073514 Ornithorhynchus anatinus 49.17 5.00e-122 431.00
IUUC-Ocu-074914 Oryctolagus cuniculus 55.80 0.00e+00 676.00
IUUC-Ola-086606 Oryzias latipes 62.29 0.00e+00 825.00
IUUC-Oga-088632 Otolemur garnettii 51.81 0.00e+00 677.00
IUUC-Oar-090320 Ovis aries 49.87 0.00e+00 653.00
IUUC-Ptr-091175 Pan troglodytes 56.52 0.00e+00 692.00
IUUC-Pan-092003 Papio anubis 57.38 0.00e+00 688.00
IUUC-Psi-093719 Pelodiscus sinensis 53.04 0.00e+00 752.00
IUUC-Pma-094390 Petromyzon marinus 49.33 1.00e-100 359.00
IUUC-Pfo-096911 Poecilia formosa 65.54 0.00e+00 912.00
IUUC-Pab-097562 Pongo abelii 56.33 0.00e+00 693.00
IUUC-Pca-100748 Procavia capensis 42.40 1.00e-56 214.00
IUUC-Pva-102168 Pteropus vampyrus 47.76 0.00e+00 637.00
IUUC-Rno-105157 Rattus norvegicus 56.45 0.00e+00 708.00
IUUC-Sha-107184 Sarcophilus harrisii 52.72 0.00e+00 753.00
IUUC-Sar-113086 Sorex araneus 47.79 7.00e-51 195.00
IUUC-Ssc-116347 Sus scrofa 51.00 0.00e+00 679.00
IUUC-Tgu-117463 Taeniopygia guttata 53.57 0.00e+00 737.00
IUUC-Tru-118348 Takifugu rubripes 64.94 0.00e+00 902.00
IUUC-Tsy-119459 Tarsius syrichta 51.30 1.00e-52 201.00
IUUC-Tni-120853 Tetraodon nigroviridis 64.24 0.00e+00 867.00
IUUC-Tbe-127361 Tupaia belangeri 52.74 8.00e-78 285.00
IUUC-Ttr-128214 Tursiops truncatus 43.98 9.00e-152 530.00
IUUC-Xtr-132479 Xenopus tropicalis 58.91 0.00e+00 673.00
Created Date 25-Jun-2017

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