iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045405

Ensembl Protein ID

ENSGGOP00000007432.2

UniProt Accession

G3QX93; G3QX93_GORGO

Protein Name

Uncharacterized protein

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000007583.2	ENSGGOT00000007630.2	ENSGGOP00000007432.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.30e-61	202.6	1131	1183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1131 QVIAMYDYAANNEDELSFSKGQLINVM--NKDDPDWWQG--EINGVTGLFPSNYVKM 1183
           6899**********************9..8899******..9*************85 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

TIVSSTYVSG GPNMWAITSE ERTKHDRQFD NLKPSGGYIT GDQARNFFLQ SGLPAPVLAE 60
IWALSDLNKD GKMDQQEFSI AMKLIKLKLQ GQQLPVVLPP IMKQPPMFSP LISARFGMGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTATAGTTT CTTCCACTTA TGTTTCAGGA GGGCCAAACA TGTGGGCTAT TACCTCTGAA 60
GAACGTACTA AGCATGACAG GCAGTTTGAT AACCTCAAAC CTTCAGGAGG TTACATAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	90.46	0.00e+00	2121.00
IUUC-Apl-004205	Anas platyrhynchos	79.69	0.00e+00	1941.00
IUUC-Aca-004287	Anolis carolinensis	79.35	0.00e+00	1669.00
IUUC-Ame-011759	Astyanax mexicanus	65.28	0.00e+00	1260.00
IUUC-Bta-013248	Bos taurus	88.32	0.00e+00	2028.00
IUUC-Cel-018490	Caenorhabditis elegans	33.26	2.00e-53	204.00
IUUC-Cja-019259	Callithrix jacchus	89.79	0.00e+00	1175.00
IUUC-Cfa-020628	Canis familiaris	90.47	0.00e+00	2127.00
IUUC-Cpo-022427	Cavia porcellus	77.24	0.00e+00	2526.00
IUUC-Csa-023122	Chlorocebus sabaeus	94.13	0.00e+00	2187.00
IUUC-Cho-024969	Choloepus hoffmanni	54.06	0.00e+00	1158.00
IUUC-Cin-025435	Ciona intestinalis	44.03	0.00e+00	915.00
IUUC-Csv-026290	Ciona savignyi	54.50	0.00e+00	727.00
IUUC-Cne-026918	Cryptococcus neoformans	35.53	2.00e-38	155.00
IUUC-Cme-027247	Cyanidioschyzon merolae	28.32	1.00e-10	61.20
IUUC-Dre-027849	Danio rerio	65.18	0.00e+00	1217.00
IUUC-Dno-029419	Dasypus novemcinctus	90.38	0.00e+00	2117.00
IUUC-Dor-030504	Dipodomys ordii	78.85	0.00e+00	1701.00
IUUC-Dme-032099	Drosophila melanogaster	33.19	1.00e-57	218.00
IUUC-Eca-034196	Equus caballus	88.35	0.00e+00	2019.00
IUUC-Eeu-034972	Erinaceus europaeus	68.87	0.00e+00	641.00
IUUC-Fca-035757	Felis catus	91.20	0.00e+00	2143.00
IUUC-Fal-037531	Ficedula albicollis	87.74	0.00e+00	1759.00
IUUC-Gmo-039632	Gadus morhua	51.99	0.00e+00	1222.00
IUUC-Gga-041012	Gallus gallus	76.71	0.00e+00	1866.00
IUUC-Gac-041948	Gasterosteus aculeatus	53.44	0.00e+00	1301.00
IUUC-Hsa-046833	Homo sapiens	94.78	0.00e+00	2173.00
IUUC-Lch-050094	Latimeria chalumnae	73.37	0.00e+00	1665.00
IUUC-Loc-052613	Lepisosteus oculatus	55.56	0.00e+00	1334.00
IUUC-Laf-053798	Loxodonta africana	82.87	0.00e+00	1385.00
IUUC-Mcc-054709	Macaca mulatta	94.30	0.00e+00	2194.00
IUUC-Meu-056396	Macropus eugenii	80.04	0.00e+00	1542.00
IUUC-Mla-059128	Melampsora laricipopulina	34.81	7.00e-40	160.00
IUUC-Mga-059997	Meleagris gallopavo	81.48	0.00e+00	1995.00
IUUC-Mvi-060268	Microbotryum violaceum	30.08	5.00e-45	177.00
IUUC-Mmr-060891	Microcebus murinus	91.92	0.00e+00	2174.00
IUUC-Mdo-062019	Monodelphis domestica	57.14	0.00e+00	1374.00
IUUC-Mmu-064226	Mus musculus	85.12	0.00e+00	2089.00
IUUC-Mpu-066431	Mustela putorius furo	90.05	0.00e+00	2106.00
IUUC-Mlu-068190	Myotis lucifugus	90.47	0.00e+00	2122.00
IUUC-Nle-070116	Nomascus leucogenys	91.08	0.00e+00	1734.00
IUUC-Opr-070815	Ochotona princeps	76.18	0.00e+00	1725.00
IUUC-Ont-071752	Oreochromis niloticus	52.86	0.00e+00	1280.00
IUUC-Oan-073390	Ornithorhynchus anatinus	55.16	0.00e+00	1314.00
IUUC-Ola-087489	Oryzias latipes	53.04	0.00e+00	1258.00
IUUC-Oga-088449	Otolemur garnettii	90.13	0.00e+00	2086.00
IUUC-Oar-090275	Ovis aries	88.89	0.00e+00	2072.00
IUUC-Ptr-091667	Pan troglodytes	94.54	0.00e+00	2167.00
IUUC-Pan-091723	Papio anubis	90.91	0.00e+00	1860.00
IUUC-Psi-093136	Pelodiscus sinensis	80.92	0.00e+00	1929.00
IUUC-Pfo-097486	Poecilia formosa	62.84	0.00e+00	1269.00
IUUC-Pab-098755	Pongo abelii	92.01	0.00e+00	2089.00
IUUC-Pca-101134	Procavia capensis	80.03	0.00e+00	1801.00
IUUC-Pva-102433	Pteropus vampyrus	82.46	0.00e+00	1866.00
IUUC-Pgr-103473	Puccinia graminis	29.97	5.00e-38	154.00
IUUC-Ptt-103973	Puccinia triticina	25.26	3.00e-27	118.00
IUUC-Rno-105691	Rattus norvegicus	89.07	0.00e+00	2153.00
IUUC-Sha-106851	Sarcophilus harrisii	57.08	0.00e+00	1394.00
IUUC-Sar-112978	Sorex araneus	85.12	0.00e+00	1378.00
IUUC-Sre-115028	Sporisorium reilianum	36.23	3.00e-32	135.00
IUUC-Ssc-115562	Sus scrofa	83.63	0.00e+00	1913.00
IUUC-Tgu-116758	Taeniopygia guttata	80.73	0.00e+00	1972.00
IUUC-Tru-117789	Takifugu rubripes	62.78	0.00e+00	1262.00
IUUC-Tsy-119039	Tarsius syrichta	70.21	0.00e+00	1066.00
IUUC-Tni-119958	Tetraodon nigroviridis	54.37	0.00e+00	1652.00
IUUC-Tbe-127477	Tupaia belangeri	92.50	0.00e+00	761.00
IUUC-Ttr-129196	Tursiops truncatus	88.71	0.00e+00	2043.00
IUUC-Uma-129456	Ustilago maydis	31.91	1.00e-30	129.00
IUUC-Vpa-130035	Vicugna pacos	80.69	0.00e+00	634.00
IUUC-Xtr-132905	Xenopus tropicalis	58.57	0.00e+00	1419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence