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Tag Content
UUCD2 ID IUUC-Mcc-055693
UUCD1 version UUC-MaM-01091
Ensembl Protein ID ENSMMUP00000003941.3
UniProt Accession F7GZU8; F7GZU8_MACMU
Genbank Protein ID ENSMMUP00000003941
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03023739
Gene Name USP19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000002948.3 ENSMMUT00000071681.1 ENSMMUP00000045441.1
ENSMMUG00000002948.3 ENSMMUT00000004177.3 ENSMMUP00000003941.3
ENSMMUG00000002948.3 ENSMMUT00000004176.3 ENSMMUP00000003940.3
ENSMMUG00000002948.3 ENSMMUT00000068644.1 ENSMMUP00000042067.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.60e-115 384.6 588 1305
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++ +++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 588  TGLVNLGNTCFMNSVIQSLSNTRELRDFFHDrSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 674
           7*****************************999****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c++vs +++p
   Q: 675  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDP 759
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 760  FLYLPVPLPQKQKVLPVfyfarephskpikflvsvskenstasevldslsqsvrvkpenlrlaeviknrfhrvflpshsldtvspsd 846
           ************87666********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 847  mllcfellspelakervvvlevqqrpqvpsvpiskcaacqrkqqsedeklkrctrcyrvgycnqlcqkthwpdhkglcrpenigypf 933
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 934  lvsvpasrltyarlaqllegyarysvsvfqppfqpgrmalesqspgcttllstgsleagdserdpiqppelqlvtpmaegdtglprv 1020
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1021 waapdrgpvpstsgisseilasgptevgslpagervsrpeaavpgyqhpseamnahtpqffiykidssnreqrledkgdtplelgdd 1107
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ft++e l  e+++yc++ck+++ea+k+l l++lP+vL
   Q: 1108 cslalvwrnnerlqefvlvaskelecaedpgsageaaraghfTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVL 1194
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ vefp + Ldls+fc+ ++e+q    +Y+L+av++H+G++ +GHY+a+++  +++        W l
   Q: 1195 IVQLKRFSFRSFIWRD-KINDLVEFPVRnLDLSKFCIGQKEEQ--LPSYDLYAVINHYGGMIGGHYTACARLPNDRssqrsdvgWRL 1278
           ************8886.**********9**********99888..9**************************544445566777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1279 FDDSTVTTVDESQVVT---RYAYVLFYRRR 1305
           ****************...********996 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MSGGASATGP RRGPPGLEDA TSKKRQKDRA NQESKDGDPR KETGSRYVAQ AGVELLASGD 60
PSASASCAAG ITGSCHHSRL FFPSLSGSAS TPREEQTKEG ACEDPHDLLA TPPPELLLDW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055693|DUB,USP|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCTGCAACT CGCCTGCTTG GCCGCAGCGG GGAGGCCGCA ACGCACTGCC GCGGCGGCCT 60
GTTCAAGGTC ACGGGCCGTG CCAGCCCCTA CCCCTAGTGT CCCGCAGCGT GCCAGCCCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055693|DUB,USP|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0046872--F:metal ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0050821--P:protein stabilization
GO:1900037--P:regulation of cellular response to hypoxia
GO:1904292--P:regulation of ERAD pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001999 Ailuropoda melanoleuca 89.16 0.00e+00 2342.00
IUUC-Apl-003368 Anas platyrhynchos 66.74 0.00e+00 1721.00
IUUC-Aca-004267 Anolis carolinensis 67.02 0.00e+00 1636.00
IUUC-Ame-010970 Astyanax mexicanus 70.14 0.00e+00 1342.00
IUUC-Bta-012905 Bos taurus 88.29 0.00e+00 2348.00
IUUC-Cel-018257 Caenorhabditis elegans 43.24 9.00e-93 335.00
IUUC-Cja-018789 Callithrix jacchus 95.21 0.00e+00 2511.00
IUUC-Cfa-021004 Canis familiaris 89.45 0.00e+00 2357.00
IUUC-Cpo-021529 Cavia porcellus 84.44 0.00e+00 2235.00
IUUC-Csa-024035 Chlorocebus sabaeus 98.35 0.00e+00 2454.00
IUUC-Cho-025036 Choloepus hoffmanni 77.90 0.00e+00 1176.00
IUUC-Cin-025451 Ciona intestinalis 43.41 8.00e-86 312.00
IUUC-Csv-025931 Ciona savignyi 36.59 6.00e-111 394.00
IUUC-Dre-028556 Danio rerio 67.85 0.00e+00 1325.00
IUUC-Dno-029240 Dasypus novemcinctus 87.99 0.00e+00 2063.00
IUUC-Dor-030495 Dipodomys ordii 95.76 0.00e+00 1206.00
IUUC-Ete-032741 Echinops telfairi 92.00 0.00e+00 1870.00
IUUC-Eca-033661 Equus caballus 88.25 0.00e+00 2284.00
IUUC-Eeu-034648 Erinaceus europaeus 90.17 0.00e+00 818.00
IUUC-Fca-035646 Felis catus 88.80 0.00e+00 2338.00
IUUC-Fal-037094 Ficedula albicollis 68.66 0.00e+00 1679.00
IUUC-Gmo-038869 Gadus morhua 72.70 0.00e+00 850.00
IUUC-Gga-041170 Gallus gallus 66.11 0.00e+00 1623.00
IUUC-Gac-041901 Gasterosteus aculeatus 65.72 0.00e+00 1315.00
IUUC-Ggo-044708 Gorilla gorilla 97.08 0.00e+00 2545.00
IUUC-Hsa-046791 Homo sapiens 97.89 0.00e+00 2068.00
IUUC-Itr-048892 Ictidomys tridecemlineatus 87.59 0.00e+00 2240.00
IUUC-Lch-050456 Latimeria chalumnae 50.93 0.00e+00 1140.00
IUUC-Loc-052861 Lepisosteus oculatus 57.22 0.00e+00 1144.00
IUUC-Laf-053788 Loxodonta africana 86.35 0.00e+00 2196.00
IUUC-Meu-055921 Macropus eugenii 78.75 0.00e+00 1470.00
IUUC-Mga-059879 Meleagris gallopavo 65.67 0.00e+00 1687.00
IUUC-Mmr-060802 Microcebus murinus 89.92 0.00e+00 2370.00
IUUC-Mdo-061856 Monodelphis domestica 79.73 0.00e+00 1575.00
IUUC-Mmu-063874 Mus musculus 85.29 0.00e+00 2237.00
IUUC-Mpu-066166 Mustela putorius furo 89.25 0.00e+00 2341.00
IUUC-Nle-070161 Nomascus leucogenys 96.86 0.00e+00 2602.00
IUUC-Opr-071015 Ochotona princeps 92.73 0.00e+00 1942.00
IUUC-Ont-072308 Oreochromis niloticus 67.10 0.00e+00 1376.00
IUUC-Oan-072723 Ornithorhynchus anatinus 65.99 0.00e+00 1525.00
IUUC-Ocu-073938 Oryctolagus cuniculus 89.53 0.00e+00 2330.00
IUUC-Ola-086375 Oryzias latipes 68.26 0.00e+00 1360.00
IUUC-Oga-088297 Otolemur garnettii 89.62 0.00e+00 2300.00
IUUC-Oar-089675 Ovis aries 79.12 0.00e+00 2043.00
IUUC-Ptr-091621 Pan troglodytes 97.70 0.00e+00 2067.00
IUUC-Pan-092118 Papio anubis 96.25 0.00e+00 2596.00
IUUC-Pma-094154 Petromyzon marinus 52.02 2.00e-115 409.00
IUUC-Pfo-097246 Poecilia formosa 58.61 0.00e+00 1404.00
IUUC-Pab-098551 Pongo abelii 96.93 0.00e+00 2046.00
IUUC-Pca-100158 Procavia capensis 82.91 0.00e+00 2169.00
IUUC-Pva-103160 Pteropus vampyrus 87.82 0.00e+00 2239.00
IUUC-Rno-105355 Rattus norvegicus 85.93 0.00e+00 2240.00
IUUC-Sha-107057 Sarcophilus harrisii 71.45 0.00e+00 1852.00
IUUC-Sar-113011 Sorex araneus 89.75 0.00e+00 1519.00
IUUC-Ssc-115761 Sus scrofa 88.81 0.00e+00 2391.00
IUUC-Tgu-116956 Taeniopygia guttata 63.24 0.00e+00 797.00
IUUC-Tru-118739 Takifugu rubripes 67.05 0.00e+00 1357.00
IUUC-Tsy-118827 Tarsius syrichta 80.10 0.00e+00 1227.00
IUUC-Tni-119921 Tetraodon nigroviridis 60.59 0.00e+00 1372.00
IUUC-Tbe-128017 Tupaia belangeri 91.55 0.00e+00 1925.00
IUUC-Ttr-128869 Tursiops truncatus 86.85 0.00e+00 2223.00
IUUC-Vpa-130427 Vicugna pacos 95.94 0.00e+00 933.00
IUUC-Xtr-132734 Xenopus tropicalis 60.42 0.00e+00 1555.00
Created Date 25-Jun-2017

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