iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020290

Ensembl Protein ID

ENSCAFP00000001854.3

UniProt Accession

E2RAT0; E2RAT0_CANLF

Genbank Protein ID

ENSCAFP00000001854

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007306

Gene Name

GRAP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001296.3	ENSCAFT00000002006.3	ENSCAFP00000001854.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.70e-30	103.2	263	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++lyd+ea +ddeL +++G+vv+v+  ++ +  W+ g   l++k GlfP+n+v+ 
   Q: 263  RALYDFEALEDDELGFRSGEVVEVL--DSSNPSWWTG--RLHNKLGLFPANYVAP 313
           79***********************..999*******..8************985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEAIAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPEWFH 60
EGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGCCA TCGCCAAGTT TGACTTCACC GCCTCAGGTG AGGATGAACT GAGCTTTCAC 60
ACCGGAGATG TTCTGAAGGT AGGTGACGTG GGGCCCTGAG GGGAGGGGGC CCTGGGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005768--C:endosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001994	Ailuropoda melanoleuca	96.52	1.00e-175	608.00
IUUC-Apl-003684	Anas platyrhynchos	61.26	4.00e-109	387.00
IUUC-Aca-005371	Anolis carolinensis	56.07	1.00e-94	339.00
IUUC-Ame-011392	Astyanax mexicanus	45.22	3.00e-69	254.00
IUUC-Bta-013508	Bos taurus	88.29	8.00e-158	549.00
IUUC-Cja-019613	Callithrix jacchus	76.97	8.00e-64	235.00
IUUC-Cpo-022534	Cavia porcellus	84.71	8.00e-162	562.00
IUUC-Csa-023438	Chlorocebus sabaeus	86.06	8.00e-160	556.00
IUUC-Cho-024466	Choloepus hoffmanni	65.76	5.00e-84	303.00
IUUC-Dre-027927	Danio rerio	49.52	2.00e-78	285.00
IUUC-Dno-029894	Dasypus novemcinctus	87.35	8.00e-164	569.00
IUUC-Dor-030493	Dipodomys ordii	95.42	2.00e-84	305.00
IUUC-Ete-032335	Echinops telfairi	76.15	2.00e-130	458.00
IUUC-Eca-033750	Equus caballus	93.67	6.00e-166	576.00
IUUC-Eeu-034884	Erinaceus europaeus	73.42	8.00e-117	412.00
IUUC-Fca-036001	Felis catus	95.25	9.00e-169	585.00
IUUC-Fal-036692	Ficedula albicollis	60.54	1.00e-106	379.00
IUUC-Gmo-039524	Gadus morhua	63.95	1.00e-53	203.00
IUUC-Gac-041301	Gasterosteus aculeatus	44.81	9.00e-73	266.00
IUUC-Ggo-045424	Gorilla gorilla	86.06	1.00e-159	555.00
IUUC-Hsa-045808	Homo sapiens	86.36	2.00e-160	558.00
IUUC-Itr-048000	Ictidomys tridecemlineatus	86.81	6.00e-154	536.00
IUUC-Lch-049610	Latimeria chalumnae	52.52	4.00e-79	288.00
IUUC-Loc-052925	Lepisosteus oculatus	49.85	4.00e-78	284.00
IUUC-Laf-054004	Loxodonta africana	88.07	8.00e-165	572.00
IUUC-Mcc-055020	Macaca mulatta	86.36	2.00e-160	558.00
IUUC-Meu-056169	Macropus eugenii	68.84	1.00e-123	435.00
IUUC-Mga-059483	Meleagris gallopavo	60.60	8.00e-111	393.00
IUUC-Mmr-061755	Microcebus murinus	89.88	4.00e-168	583.00
IUUC-Mdo-062504	Monodelphis domestica	69.32	3.00e-131	461.00
IUUC-Mmu-063557	Mus musculus	83.18	1.00e-152	532.00
IUUC-Mpu-066852	Mustela putorius furo	95.57	5.00e-172	596.00
IUUC-Mlu-067510	Myotis lucifugus	93.08	1.00e-166	578.00
IUUC-Nle-069691	Nomascus leucogenys	86.97	1.00e-162	565.00
IUUC-Opr-070271	Ochotona princeps	84.86	9.00e-150	522.00
IUUC-Ont-072651	Oreochromis niloticus	43.50	9.00e-70	256.00
IUUC-Oan-073183	Ornithorhynchus anatinus	73.62	2.00e-126	445.00
IUUC-Ocu-074899	Oryctolagus cuniculus	80.50	2.00e-136	478.00
IUUC-Ola-086462	Oryzias latipes	46.71	9.00e-73	266.00
IUUC-Oga-088553	Otolemur garnettii	89.33	1.00e-163	568.00
IUUC-Oar-089572	Ovis aries	89.56	3.00e-166	577.00
IUUC-Ptr-090582	Pan troglodytes	86.67	6.00e-161	559.00
IUUC-Pan-092063	Papio anubis	86.36	2.00e-160	558.00
IUUC-Psi-094056	Pelodiscus sinensis	62.84	2.00e-112	398.00
IUUC-Pfo-096115	Poecilia formosa	48.09	1.00e-75	276.00
IUUC-Pab-098217	Pongo abelii	86.36	2.00e-160	557.00
IUUC-Pca-100838	Procavia capensis	87.69	9.00e-158	549.00
IUUC-Pva-102559	Pteropus vampyrus	92.69	3.00e-131	461.00
IUUC-Rno-105926	Rattus norvegicus	72.21	2.00e-129	455.00
IUUC-Sha-106948	Sarcophilus harrisii	73.04	2.00e-123	435.00
IUUC-Ssc-115605	Sus scrofa	87.50	8.00e-158	549.00
IUUC-Tgu-117211	Taeniopygia guttata	59.39	9.00e-108	383.00
IUUC-Tru-118347	Takifugu rubripes	65.99	1.00e-56	213.00
IUUC-Tsy-119441	Tarsius syrichta	87.58	3.00e-163	567.00
IUUC-Tni-119732	Tetraodon nigroviridis	47.13	3.00e-73	268.00
IUUC-Tbe-127289	Tupaia belangeri	80.88	8.00e-136	476.00
IUUC-Ttr-128961	Tursiops truncatus	76.36	8.00e-142	496.00
IUUC-Vpa-130320	Vicugna pacos	78.72	7.00e-81	293.00
IUUC-Xtr-131814	Xenopus tropicalis	47.58	1.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence