iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-089090

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03024852

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000008689.2	ENSOGAT00000008693.2	ENSOGAP00000007788.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-40	134.5	237	277
UBD/Beta-Prp	3.50e-52	177.4	191	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 237  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 277
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 191  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 278
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 279  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 367
           ******************************************95333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 368  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 396
           ***************************** PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLNYCSICA EIMATDGLHE NETLASLKIE 60
AESLKGKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT AGTTAATGTA TTTGGCTCGT GTGATAAATG TTTCAAACAA 60
AGGGCCCTGA GACCAGTTTT CAAGAAATCT CAACAACTCA ACTACTGCTC AATATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.94	0.00e+00	759.00
IUUC-Apl-003399	Anas platyrhynchos	98.10	0.00e+00	645.00
IUUC-Aca-004861	Anolis carolinensis	92.44	0.00e+00	773.00
IUUC-Ame-011851	Astyanax mexicanus	91.22	0.00e+00	678.00
IUUC-Bta-012438	Bos taurus	98.59	0.00e+00	725.00
IUUC-Cel-018408	Caenorhabditis elegans	64.55	3.00e-137	481.00
IUUC-Cja-019086	Callithrix jacchus	98.48	0.00e+00	807.00
IUUC-Cfa-021255	Canis familiaris	96.46	0.00e+00	752.00
IUUC-Cpo-021398	Cavia porcellus	96.73	0.00e+00	796.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.59	0.00e+00	724.00
IUUC-Cin-025305	Ciona intestinalis	57.61	9.00e-130	456.00
IUUC-Csv-026058	Ciona savignyi	57.77	7.00e-126	443.00
IUUC-Dre-028432	Danio rerio	84.63	0.00e+00	675.00
IUUC-Dno-029958	Dasypus novemcinctus	87.24	3.00e-149	520.00
IUUC-Dor-031013	Dipodomys ordii	98.45	2.00e-151	528.00
IUUC-Dme-031889	Drosophila melanogaster	68.21	3.00e-147	514.00
IUUC-Eca-033977	Equus caballus	92.95	0.00e+00	760.00
IUUC-Eeu-035079	Erinaceus europaeus	97.21	0.00e+00	793.00
IUUC-Fca-035693	Felis catus	91.73	0.00e+00	755.00
IUUC-Fal-037345	Ficedula albicollis	97.46	0.00e+00	721.00
IUUC-Gmo-039222	Gadus morhua	90.70	0.00e+00	654.00
IUUC-Gga-040320	Gallus gallus	97.75	0.00e+00	722.00
IUUC-Gac-042644	Gasterosteus aculeatus	90.99	0.00e+00	682.00
IUUC-Ggo-044489	Gorilla gorilla	94.47	0.00e+00	768.00
IUUC-Hsa-046434	Homo sapiens	98.49	0.00e+00	812.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	93.08	4.00e-175	606.00
IUUC-Loc-052790	Lepisosteus oculatus	90.10	0.00e+00	719.00
IUUC-Laf-054255	Loxodonta africana	97.47	0.00e+00	798.00
IUUC-Mcc-055610	Macaca mulatta	97.97	0.00e+00	803.00
IUUC-Meu-056819	Macropus eugenii	85.79	0.00e+00	689.00
IUUC-Mga-059740	Meleagris gallopavo	86.35	0.00e+00	709.00
IUUC-Mmr-061221	Microcebus murinus	98.49	0.00e+00	814.00
IUUC-Mdo-062619	Monodelphis domestica	97.18	0.00e+00	718.00
IUUC-Mmu-064266	Mus musculus	98.74	0.00e+00	815.00
IUUC-Mpu-065766	Mustela putorius furo	98.68	5.00e-180	622.00
IUUC-Mlu-067221	Myotis lucifugus	90.48	0.00e+00	745.00
IUUC-Nle-069515	Nomascus leucogenys	99.06	0.00e+00	655.00
IUUC-Opr-070195	Ochotona princeps	90.38	0.00e+00	724.00
IUUC-Ont-071535	Oreochromis niloticus	78.59	3.00e-171	593.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	2.00e-107	380.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.01	2.00e-180	624.00
IUUC-Ola-086578	Oryzias latipes	92.09	0.00e+00	647.00
IUUC-Oar-090017	Ovis aries	92.17	0.00e+00	741.00
IUUC-Ptr-091280	Pan troglodytes	89.42	0.00e+00	721.00
IUUC-Pan-092198	Papio anubis	98.44	0.00e+00	655.00
IUUC-Psi-093030	Pelodiscus sinensis	85.15	0.00e+00	715.00
IUUC-Pma-094140	Petromyzon marinus	83.10	1.00e-105	375.00
IUUC-Pfo-097182	Poecilia formosa	91.83	0.00e+00	661.00
IUUC-Pab-098157	Pongo abelii	98.87	0.00e+00	729.00
IUUC-Pca-100988	Procavia capensis	77.33	1.00e-170	592.00
IUUC-Pva-102232	Pteropus vampyrus	86.08	2.00e-175	607.00
IUUC-Rno-105526	Rattus norvegicus	95.24	0.00e+00	689.00
IUUC-Sha-106754	Sarcophilus harrisii	95.97	0.00e+00	753.00
IUUC-Ssc-115390	Sus scrofa	98.24	0.00e+00	810.00
IUUC-Tgu-117377	Taeniopygia guttata	86.84	0.00e+00	699.00
IUUC-Tru-117938	Takifugu rubripes	91.83	0.00e+00	649.00
IUUC-Tsy-119392	Tarsius syrichta	84.38	0.00e+00	661.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.54	2.00e-164	571.00
IUUC-Tbe-127469	Tupaia belangeri	95.24	0.00e+00	728.00
IUUC-Ttr-128252	Tursiops truncatus	94.97	0.00e+00	769.00
IUUC-Vpa-130173	Vicugna pacos	80.47	1.00e-156	545.00
IUUC-Xtr-131803	Xenopus tropicalis	91.18	0.00e+00	724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence