iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000008473.1	ENSONIT00000010659.1	ENSONIP00000010650.1
ENSONIG00000008473.1	ENSONIT00000010660.1	ENSONIP00000010651.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-10	41.4	757	809

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           k ++ly  +a++d eL++ +G + + + +++ + gWl+g  +l g+ Gl+Pen+ve
   Q: 757  KARALYACKAEHDSELSFIAGTIFENV-HASREPGWLEG--TLDGRTGLIPENYVE 809
           6789***********************.***********..8*************8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

LIFSVLSGLS TAKRKFADSL NDFKFQCIGD AETDDEICIA KSLQEFAAVL QNLEDERTRM 60
IENANDVLIL PLERFRKEQI SAAKEAKKKY DKETEKYCAV LEKHLSLSAK KKEAHLLEAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAATATTT TCACTGTTTA TATGCTGCGT GCTGCTCTTT CCATCTAATT CTGAGACTTC 60
ACTTTTCCAA CGCAGTTTCA GGAAACTTGG TCAGAGTGGA CCCTCCTTCT TTTATCCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR030061--RHG26
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005096--F:GTPase activator activity
GO:0030036--P:actin cytoskeleton organization
GO:0051056--P:regulation of small GTPase mediated signal transduction
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001613	Ailuropoda melanoleuca	77.49	0.00e+00	872.00
IUUC-Apl-003321	Anas platyrhynchos	76.84	0.00e+00	854.00
IUUC-Aca-004570	Anolis carolinensis	77.97	0.00e+00	900.00
IUUC-Ame-011422	Astyanax mexicanus	84.10	0.00e+00	938.00
IUUC-Bta-013262	Bos taurus	77.19	0.00e+00	876.00
IUUC-Cja-019208	Callithrix jacchus	77.66	0.00e+00	874.00
IUUC-Cfa-020928	Canis familiaris	77.49	0.00e+00	873.00
IUUC-Cpo-021338	Cavia porcellus	77.66	0.00e+00	873.00
IUUC-Csa-023570	Chlorocebus sabaeus	77.49	0.00e+00	872.00
IUUC-Dno-029143	Dasypus novemcinctus	75.47	0.00e+00	863.00
IUUC-Dor-030697	Dipodomys ordii	77.14	0.00e+00	865.00
IUUC-Ete-032645	Echinops telfairi	71.00	0.00e+00	753.00
IUUC-Eca-033791	Equus caballus	77.31	0.00e+00	868.00
IUUC-Eeu-035202	Erinaceus europaeus	58.61	1.00e-88	321.00
IUUC-Fca-036131	Felis catus	78.01	0.00e+00	876.00
IUUC-Fal-037129	Ficedula albicollis	77.57	0.00e+00	862.00
IUUC-Gga-041023	Gallus gallus	78.01	0.00e+00	884.00
IUUC-Ggo-044863	Gorilla gorilla	77.39	0.00e+00	867.00
IUUC-Hsa-046471	Homo sapiens	77.84	0.00e+00	875.00
IUUC-Itr-049060	Ictidomys tridecemlineatus	77.86	0.00e+00	892.00
IUUC-Lch-050300	Latimeria chalumnae	78.75	0.00e+00	849.00
IUUC-Loc-052782	Lepisosteus oculatus	79.46	0.00e+00	978.00
IUUC-Laf-053585	Loxodonta africana	78.29	0.00e+00	863.00
IUUC-Mcc-055458	Macaca mulatta	77.49	0.00e+00	873.00
IUUC-Meu-056107	Macropus eugenii	65.91	0.00e+00	702.00
IUUC-Mga-059914	Meleagris gallopavo	75.87	0.00e+00	848.00
IUUC-Mmr-060728	Microcebus murinus	77.74	0.00e+00	867.00
IUUC-Mdo-062387	Monodelphis domestica	76.49	0.00e+00	902.00
IUUC-Mmu-063756	Mus musculus	76.74	0.00e+00	893.00
IUUC-Nle-069043	Nomascus leucogenys	72.29	0.00e+00	684.00
IUUC-Opr-071168	Ochotona princeps	66.25	0.00e+00	724.00
IUUC-Oan-073441	Ornithorhynchus anatinus	75.80	0.00e+00	774.00
IUUC-Ocu-073915	Oryctolagus cuniculus	77.66	0.00e+00	896.00
IUUC-Ola-086319	Oryzias latipes	86.45	0.00e+00	1013.00
IUUC-Oar-089349	Ovis aries	76.87	0.00e+00	876.00
IUUC-Ptr-091027	Pan troglodytes	78.03	0.00e+00	869.00
IUUC-Pan-092791	Papio anubis	77.49	0.00e+00	874.00
IUUC-Psi-093144	Pelodiscus sinensis	78.62	0.00e+00	900.00
IUUC-Pab-097783	Pongo abelii	77.49	0.00e+00	872.00
IUUC-Pva-102980	Pteropus vampyrus	78.01	0.00e+00	900.00
IUUC-Rno-105142	Rattus norvegicus	76.91	0.00e+00	901.00
IUUC-Sha-107213	Sarcophilus harrisii	77.76	0.00e+00	905.00
IUUC-Tru-117767	Takifugu rubripes	85.39	0.00e+00	1047.00
IUUC-Tsy-119150	Tarsius syrichta	71.38	0.00e+00	852.00
IUUC-Tni-119893	Tetraodon nigroviridis	86.30	0.00e+00	825.00
IUUC-Ttr-129028	Tursiops truncatus	64.72	0.00e+00	683.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence