iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004559

UUCD1 version

UUC-AnC-00128

Ensembl Protein ID

ENSACAP00000007149.2

UniProt Accession

H9GCJ0; H9GCJ0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000007251.2	ENSACAT00000007304.2	ENSACAP00000007149.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-08	35.1	246	284
UBD/Alpha-Helix/CUE	6.20e-12	45.2	361	402

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC++ ++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 246  CAICWDAMQA-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 284
           ********99.9*****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y +i ++L ++t s+e +++n+Leg 
   Q: 361  QLNAMAHQIQEMFPQVPYHLILQDL-QLTRSVEITTDNILEGR 402
           5889*********************.***************95 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MLIAKLIQGI VFGSLRVSER QHLKDKFWNF IFYKFIFIFG VLNVQTVEEV VMWCLWFSGL 60
VFLHLMVQLC KDRFEYLSFS PTTPMNSHIR VLTLLVAMLL SCCGLGIVCG VIGYTHGMHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAATTAATCA ATTGATCAAA ACTCTGGCTT TGAAAGCAGT GCCCCTTTCT GGTTCTTGCT 60
AAACATCAGG TATGTATTCT TTTTGTTCTT AGGTGCTGGT GAATACGGCA TGCTGTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	84.90	0.00e+00	909.00
IUUC-Apl-003404	Anas platyrhynchos	88.47	0.00e+00	915.00
IUUC-Ame-011640	Astyanax mexicanus	76.92	0.00e+00	745.00
IUUC-Bta-012980	Bos taurus	85.64	0.00e+00	920.00
IUUC-Cja-019577	Callithrix jacchus	85.64	0.00e+00	923.00
IUUC-Cfa-020793	Canis familiaris	84.18	0.00e+00	914.00
IUUC-Cpo-022387	Cavia porcellus	86.00	0.00e+00	900.00
IUUC-Csa-023168	Chlorocebus sabaeus	85.82	0.00e+00	927.00
IUUC-Cho-024433	Choloepus hoffmanni	87.00	0.00e+00	783.00
IUUC-Cin-025215	Ciona intestinalis	50.49	3.00e-140	491.00
IUUC-Csv-026133	Ciona savignyi	50.78	1.00e-129	456.00
IUUC-Dre-027594	Danio rerio	74.90	0.00e+00	702.00
IUUC-Dno-029407	Dasypus novemcinctus	85.45	0.00e+00	892.00
IUUC-Dor-030961	Dipodomys ordii	85.82	0.00e+00	914.00
IUUC-Ete-032962	Echinops telfairi	77.82	0.00e+00	753.00
IUUC-Eca-033683	Equus caballus	83.30	0.00e+00	872.00
IUUC-Eeu-034515	Erinaceus europaeus	88.89	5.00e-72	265.00
IUUC-Fca-035398	Felis catus	87.40	0.00e+00	892.00
IUUC-Fal-036758	Ficedula albicollis	82.47	0.00e+00	871.00
IUUC-Gmo-039014	Gadus morhua	74.80	0.00e+00	701.00
IUUC-Gga-040575	Gallus gallus	87.90	0.00e+00	955.00
IUUC-Gac-041414	Gasterosteus aculeatus	73.33	0.00e+00	684.00
IUUC-Hsa-046272	Homo sapiens	85.64	0.00e+00	926.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	85.45	0.00e+00	900.00
IUUC-Lch-050491	Latimeria chalumnae	81.34	0.00e+00	795.00
IUUC-Lpe-051413	Leersia perrieri	44.44	2.00e-12	64.70
IUUC-Loc-052758	Lepisosteus oculatus	79.92	0.00e+00	761.00
IUUC-Laf-053452	Loxodonta africana	85.64	0.00e+00	924.00
IUUC-Mcc-055820	Macaca mulatta	85.64	0.00e+00	922.00
IUUC-Meu-056726	Macropus eugenii	81.80	0.00e+00	699.00
IUUC-Mga-059937	Meleagris gallopavo	87.55	0.00e+00	922.00
IUUC-Mmr-060730	Microcebus murinus	85.64	0.00e+00	901.00
IUUC-Mdo-062771	Monodelphis domestica	87.55	0.00e+00	913.00
IUUC-Mmu-064219	Mus musculus	85.28	0.00e+00	922.00
IUUC-Mpu-066796	Mustela putorius furo	84.91	0.00e+00	916.00
IUUC-Mlu-068189	Myotis lucifugus	83.82	0.00e+00	866.00
IUUC-Nle-069239	Nomascus leucogenys	85.64	0.00e+00	925.00
IUUC-Opr-070702	Ochotona princeps	77.70	3.00e-123	435.00
IUUC-Ont-072033	Oreochromis niloticus	77.12	0.00e+00	749.00
IUUC-Oan-073717	Ornithorhynchus anatinus	81.03	0.00e+00	821.00
IUUC-Ocu-074145	Oryctolagus cuniculus	85.27	0.00e+00	927.00
IUUC-Ogl-077929	Oryza glaberrima	43.28	2.00e-11	61.60
IUUC-Ola-087152	Oryzias latipes	74.26	0.00e+00	715.00
IUUC-Oga-088486	Otolemur garnettii	86.18	0.00e+00	906.00
IUUC-Oar-089310	Ovis aries	85.45	0.00e+00	920.00
IUUC-Ptr-090649	Pan troglodytes	85.64	0.00e+00	926.00
IUUC-Pan-091692	Papio anubis	81.27	0.00e+00	864.00
IUUC-Psi-093064	Pelodiscus sinensis	92.71	0.00e+00	765.00
IUUC-Pma-094763	Petromyzon marinus	79.06	1.00e-92	332.00
IUUC-Ppa-095969	Physcomitrella patens	29.91	1.00e-38	154.00
IUUC-Pfo-096810	Poecilia formosa	74.36	0.00e+00	715.00
IUUC-Pab-097859	Pongo abelii	85.64	0.00e+00	926.00
IUUC-Pca-100344	Procavia capensis	84.42	0.00e+00	879.00
IUUC-Pva-103114	Pteropus vampyrus	57.45	1.00e-147	516.00
IUUC-Rno-105880	Rattus norvegicus	83.36	0.00e+00	895.00
IUUC-Sha-107015	Sarcophilus harrisii	87.58	0.00e+00	897.00
IUUC-Smo-109664	Selaginella moellendorffii	30.72	1.00e-32	134.00
IUUC-Sar-113397	Sorex araneus	91.37	0.00e+00	718.00
IUUC-Ssc-115988	Sus scrofa	78.15	1.00e-121	428.00
IUUC-Tgu-116717	Taeniopygia guttata	90.91	0.00e+00	892.00
IUUC-Tru-117805	Takifugu rubripes	73.01	0.00e+00	746.00
IUUC-Tsy-119442	Tarsius syrichta	80.00	0.00e+00	822.00
IUUC-Tni-119777	Tetraodon nigroviridis	72.26	5.00e-174	603.00
IUUC-Tbe-127322	Tupaia belangeri	60.56	4.00e-95	341.00
IUUC-Ttr-128181	Tursiops truncatus	85.27	0.00e+00	920.00
IUUC-Vpa-130483	Vicugna pacos	78.54	6.00e-172	597.00
IUUC-Xtr-132614	Xenopus tropicalis	77.87	0.00e+00	726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence