iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129886

Ensembl Protein ID

EGY15743

UniProt Accession

G2XA04; G2XA04_VERDV

Genbank Protein ID

EGY15743.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

DS572709

Gene Name

VDAG_06907

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_06907	EGY15743	EGY15743

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-118	394.7	3639	3970

Active Site

Position(s)	Description	Evidence
3939	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           ++k+ +l+++f gEeg+d+gGvtre+++ l+++++++++ lf   ++d++t++pn+ sg+ n  hl +F+f+Gr++gkal++grlld+ +s+++yk++l
   Q: 3639 EMKYgKLNIRFHGEEGVDAGGVTREWFQVLARQMFDANYALFIPVSSDRTTFHPNKLSGI-NDMHLMYFKFVGRIIGKALYEGRLLDCYFSRAVYKRIL 3736
           66755899***************************************************9.56************************************ PP
   S: 102  gkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnev 200
           gk++s++d+e++dp++yksl +++en   di+++ ++ tfsv+++++g t+ ++L+p+G+ni Vt+eNk++Yv+lvve++l +++keq+e+f +Gf+e+
   Q: 3737 GKSVSVKDMESFDPDYYKSLVWMLEN---DITDI-ITETFSVEDDEFGVTTIVDLCPDGRNIAVTEENKNDYVRLVVEHKLLSSVKEQMEHFLKGFHEI 3831
           ************************99...99999.999************************************************************* PP
   S: 201  iplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.das 294
           ip el+++F+e+elelli+G ++id++d+k++t+y++ yt++s++iqwFw+++++f++ee +++LqFvTg+s++Pl+Gf+el+     ++f i++ +++
   Q: 3832 IPSELIRIFNEQELELLISGLPDIDIDDWKSNTEYHN-YTPSSQQIQWFWRAIRSFDKEELAKLLQFVTGTSKVPLNGFKELEgmngVSRFNIHRdYGN 3929
           ***********************************66.*********************************************9999666777776899 PP
   S: 295  ddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           ++rlPss+TCfn+L+LPeY+s+e+l+++L+ Ai+ + + F+
   Q: 3930 KERLPSSHTCFNQLDLPEYESYETLRSQLMKAITAGsDYFG 3970
           9********************************99866665 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MGKITKTMQP KHEETLSPWL KDFVQSACTL PLPLLPDHIA TFPTRWPFPR GDLYHWIPLL 60
NRFDNILECF SVTYKLNEGP QTGDLGCEVL LHRGLKVEEY GTEVWDMDRL RKQGYGEQGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCGTTTAAC CTCGCGGCTT GGCCGCCCCA TTTCTGAAGA TGGGGAAAAT CACCAAGACG 60
ATGCAGCCGA AGCATGAGGA GACTCTTGTG AGTCAAGTCT GAACAAACCC TTGCAACATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

vda:VDAG_06907

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	45.71	3.00e-109	389.00
IUUC-Aml-001684	Ailuropoda melanoleuca	47.62	4.00e-138	486.00
IUUC-Atr-003044	Amborella trichopoda	47.56	5.00e-137	482.00
IUUC-Apl-003729	Anas platyrhynchos	53.71	8.00e-102	361.00
IUUC-Aca-005263	Anolis carolinensis	47.63	2.00e-139	490.00
IUUC-Aly-006083	Arabidopsis lyrata	47.95	6.00e-133	468.00
IUUC-Ath-007160	Arabidopsis thaliana	47.75	4.00e-136	479.00
IUUC-Ago-008005	Ashbya gossypii	55.73	0.00e+00	712.00
IUUC-Acl-008254	Aspergillus clavatus	66.92	0.00e+00	917.00
IUUC-Afl-008712	Aspergillus flavus	57.16	0.00e+00	1184.00
IUUC-Afu-009022	Aspergillus fumigatus	34.72	0.00e+00	1199.00
IUUC-Ani-009412	Aspergillus nidulans	56.25	0.00e+00	1150.00
IUUC-Ang-009771	Aspergillus niger	55.23	0.00e+00	1185.00
IUUC-Aor-010186	Aspergillus oryzae	55.64	0.00e+00	1165.00
IUUC-Ate-010253	Aspergillus terreus	34.44	0.00e+00	1197.00
IUUC-Ame-011067	Astyanax mexicanus	47.91	3.00e-137	483.00
IUUC-Bgr-012043	Blumeria graminis	39.92	0.00e+00	1529.00
IUUC-Bta-012813	Bos taurus	47.62	3.00e-138	486.00
IUUC-Bci-013995	Botrytis cinerea	39.71	0.00e+00	1604.00
IUUC-Bdi-014884	Brachypodium distachyon	49.77	6.00e-131	462.00
IUUC-Bol-016533	Brassica oleracea	56.36	2.00e-93	333.00
IUUC-Bra-016726	Brassica rapa	47.93	2.00e-135	476.00
IUUC-Cel-018179	Caenorhabditis elegans	52.47	2.00e-130	460.00
IUUC-Cja-018741	Callithrix jacchus	47.53	5.00e-137	482.00
IUUC-Cfa-020083	Canis familiaris	47.62	4.00e-138	486.00
IUUC-Cpo-021923	Cavia porcellus	39.41	1.00e-100	361.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.12	6.00e-133	465.00
IUUC-Csa-023853	Chlorocebus sabaeus	47.62	4.00e-138	486.00
IUUC-Cho-024718	Choloepus hoffmanni	59.44	3.00e-126	446.00
IUUC-Cin-025627	Ciona intestinalis	52.24	3.00e-130	459.00
IUUC-Csv-025872	Ciona savignyi	52.00	2.00e-125	440.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	59.64	0.00e+00	2709.00
IUUC-Cne-027095	Cryptococcus neoformans	35.71	2.00e-175	609.00
IUUC-Cme-027267	Cyanidioschyzon merolae	49.77	9.00e-120	423.00
IUUC-Dre-028525	Danio rerio	45.82	2.00e-123	437.00
IUUC-Dno-029680	Dasypus novemcinctus	47.62	4.00e-138	486.00
IUUC-Dor-030902	Dipodomys ordii	49.20	5.00e-115	409.00
IUUC-Dse-031197	Dothistroma septosporum	53.43	0.00e+00	1100.00
IUUC-Dme-032122	Drosophila melanogaster	54.61	1.00e-133	471.00
IUUC-Eca-033915	Equus caballus	46.95	2.00e-136	480.00
IUUC-Eeu-034963	Erinaceus europaeus	54.36	1.00e-135	477.00
IUUC-Fca-035824	Felis catus	47.62	3.00e-138	486.00
IUUC-Fox-037756	Fusarium oxysporum	52.14	0.00e+00	2215.00
IUUC-Fso-038464	Fusarium solani	52.36	0.00e+00	2248.00
IUUC-Gmo-039073	Gadus morhua	47.24	6.00e-138	485.00
IUUC-Ggr-039946	Gaeumannomyces graminis	47.73	0.00e+00	2008.00
IUUC-Gga-040309	Gallus gallus	58.96	6.00e-107	378.00
IUUC-Gac-042430	Gasterosteus aculeatus	47.24	6.00e-138	485.00
IUUC-Gma-043112	Glycine max	44.61	5.00e-136	478.00
IUUC-Hsa-046879	Homo sapiens	47.62	4.00e-138	486.00
IUUC-Hvu-047697	Hordeum vulgare	38.14	2.00e-131	463.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	47.62	9.00e-139	486.00
IUUC-Kpa-049228	Komagataella pastoris	56.65	0.00e+00	731.00
IUUC-Lch-050252	Latimeria chalumnae	54.82	5.00e-138	485.00
IUUC-Lpe-050915	Leersia perrieri	48.35	7.00e-132	465.00
IUUC-Loc-052472	Lepisosteus oculatus	47.43	1.00e-138	488.00
IUUC-Lma-053159	Leptosphaeria maculans	55.33	0.00e+00	1157.00
IUUC-Laf-054154	Loxodonta africana	47.62	3.00e-138	486.00
IUUC-Mcc-055085	Macaca mulatta	47.62	4.00e-138	486.00
IUUC-Mor-057201	Magnaporthe oryzae	46.84	0.00e+00	1997.00
IUUC-Mpo-057597	Magnaporthe poae	48.25	0.00e+00	1444.00
IUUC-Mtr-058128	Medicago truncatula	39.01	3.00e-137	483.00
IUUC-Mla-058888	Melampsora laricipopulina	57.99	5.00e-146	508.00
IUUC-Mvi-060320	Microbotryum violaceum	50.15	0.00e+00	658.00
IUUC-Mmr-060820	Microcebus murinus	47.62	3.00e-138	486.00
IUUC-Mdo-062930	Monodelphis domestica	47.63	3.00e-139	489.00
IUUC-Mmu-063601	Mus musculus	47.62	4.00e-138	486.00
IUUC-Mac-065557	Musa acuminata	44.55	3.00e-127	449.00
IUUC-Mpu-066653	Mustela putorius furo	47.62	4.00e-138	486.00
IUUC-Mlu-067418	Myotis lucifugus	47.44	1.00e-138	488.00
IUUC-Nfi-068278	Neosartorya fischeri	56.60	0.00e+00	1183.00
IUUC-Ncr-068813	Neurospora crassa	46.02	0.00e+00	1865.00
IUUC-Nle-069418	Nomascus leucogenys	47.62	4.00e-138	486.00
IUUC-Ont-071300	Oreochromis niloticus	47.24	1.00e-137	484.00
IUUC-Oan-073046	Ornithorhynchus anatinus	47.64	2.00e-138	487.00
IUUC-Ocu-074178	Oryctolagus cuniculus	47.62	2.00e-138	486.00
IUUC-Oba-075252	Oryza barthii	48.33	5.00e-130	459.00
IUUC-Obr-076762	Oryza brachyantha	48.34	2.00e-130	460.00
IUUC-Ogl-077520	Oryza glaberrima	47.31	5.00e-133	468.00
IUUC-Ogu-077981	Oryza glumaepatula	48.33	3.00e-130	459.00
IUUC-Oin-079663	Oryza indica	48.33	3.00e-130	459.00
IUUC-Olo-080326	Oryza longistaminata	48.12	8.00e-129	455.00
IUUC-Ome-081289	Oryza meridionalis	48.34	3.00e-130	457.00
IUUC-Oni-082619	Oryza nivara	47.31	5.00e-133	469.00
IUUC-Opu-083428	Oryza punctata	48.55	2.00e-131	463.00
IUUC-Oru-084559	Oryza rufipogon	48.33	7.00e-130	458.00
IUUC-Osa-086251	Oryza sativa	47.31	3.00e-132	464.00
IUUC-Olu-087813	Ostreococcus lucimarinus	47.45	2.00e-115	407.00
IUUC-Oga-088903	Otolemur garnettii	47.62	5.00e-138	485.00
IUUC-Oar-090210	Ovis aries	47.62	4.00e-138	486.00
IUUC-Pan-092368	Papio anubis	46.64	4.00e-125	442.00
IUUC-Pno-094871	Phaeosphaeria nodorum	54.45	0.00e+00	1110.00
IUUC-Ppa-095657	Physcomitrella patens	38.31	8.00e-134	471.00
IUUC-Pfo-096232	Poecilia formosa	47.24	4.00e-138	486.00
IUUC-Pab-098583	Pongo abelii	47.62	4.00e-138	486.00
IUUC-Pop-099468	Populus trichocarpa	39.04	1.00e-136	480.00
IUUC-Pca-100310	Procavia capensis	61.29	3.00e-89	323.00
IUUC-Ppe-102109	Prunus persica	38.48	5.00e-137	482.00
IUUC-Pva-102116	Pteropus vampyrus	44.57	1.00e-123	438.00
IUUC-Pgr-103465	Puccinia graminis	46.85	0.00e+00	632.00
IUUC-Ptt-103813	Puccinia triticina	45.16	4.00e-169	588.00
IUUC-Pte-104018	Pyrenophora teres	34.65	0.00e+00	1243.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	34.77	0.00e+00	1236.00
IUUC-Sce-106449	Saccharomyces cerevisiae	53.51	0.00e+00	695.00
IUUC-Sha-106961	Sarcophilus harrisii	47.63	3.00e-139	489.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	42.69	0.00e+00	821.00
IUUC-Spo-108024	Schizosaccharomyces pombe	42.77	0.00e+00	825.00
IUUC-Smo-109428	Selaginella moellendorffii	40.49	2.00e-137	483.00
IUUC-Sit-110149	Setaria italica	38.08	8.00e-132	464.00
IUUC-Sly-111706	Solanum lycopersicum	46.61	4.00e-135	475.00
IUUC-Stu-112894	Solanum tuberosum	33.24	4.00e-58	218.00
IUUC-Sar-113291	Sorex araneus	55.53	4.00e-133	469.00
IUUC-Sbi-114042	Sorghum bicolor	36.97	9.00e-132	464.00
IUUC-Sre-114958	Sporisorium reilianum	58.19	6.00e-174	602.00
IUUC-Ssc-115754	Sus scrofa	47.62	5.00e-138	485.00
IUUC-Tru-118570	Takifugu rubripes	47.24	4.00e-138	486.00
IUUC-Tni-120836	Tetraodon nigroviridis	46.48	1.00e-133	470.00
IUUC-Tca-121479	Theobroma cacao	47.34	5.00e-134	472.00
IUUC-Tre-121909	Trichoderma reesei	51.81	0.00e+00	2246.00
IUUC-Tvi-122370	Trichoderma virens	51.70	0.00e+00	2214.00
IUUC-Tae-125214	Triticum aestivum	49.29	3.00e-128	452.00
IUUC-Tur-126774	Triticum urartu	30.88	2.00e-52	198.00
IUUC-Tme-127172	Tuber melanosporum	67.46	0.00e+00	901.00
IUUC-Ttr-129253	Tursiops truncatus	47.62	7.00e-138	485.00
IUUC-Uma-129355	Ustilago maydis	58.89	1.00e-177	614.00
IUUC-Vpa-130708	Vicugna pacos	47.62	8.00e-138	484.00
IUUC-Vvi-131170	Vitis vinifera	48.06	3.00e-137	481.00
IUUC-Xtr-132123	Xenopus tropicalis	45.90	1.00e-129	458.00
IUUC-Xma-133869	Xiphophorus maculatus	47.24	4.00e-138	486.00
IUUC-Yli-134657	Yarrowia lipolytica	58.54	0.00e+00	768.00
IUUC-Zma-135595	Zea mays	39.97	3.00e-134	473.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence