iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062194

UUCD1 version

UUC-MoD-00457

Ensembl Protein ID

ENSMODP00000006460.3

UniProt Accession

F6YN15; F6YN15_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000005239.3	ENSMODT00000006595.3	ENSMODP00000006460.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-105	353.9	791	1128

Active Site

Position(s)	Description	Evidence
1096	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 791  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYE 876
           689**********99**9************************************9999999999965.999**************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N
   Q: 877  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEMYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKLGGKDIPVTSAN 960
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++d+p+i+ Fw+v+e+
   Q: 961  RIAYIHLVADYRLNKQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSADHPVIKIFWKVVES 1047
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd drlP+++TC+n+LkLPe+  ++ l++kLlyAie ++gFels
   Q: 1048 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlDRLPTASTCMNLLKLPEFYDENLLRSKLLYAIECAAGFELS 1128
           ****************************88.*****99999**************************************985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MFSFEGEFKT RPKVSLGGAS RKVYHYPFPS STSRSSHVTN PYNQVKQIHM LVMPNSVPLV 60
YHLSEKEEKA SLLHRTQEER RKREEERRRL KNAIIIQSFV RGYRDRKQQY SIQRSEFDQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGCT TTGAAGGGGA GTTCAAAACC AGGCCCAAGG TGTCCCTTGG AGGAGCAAGT 60
AGGAAGGTAA GAGACCTGCC CCTTCTTGGC CGCCCGGGAA TTTCGCCACA TCTCCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	89.27	0.00e+00	1853.00
IUUC-Apl-003731	Anas platyrhynchos	90.79	0.00e+00	1967.00
IUUC-Aca-005248	Anolis carolinensis	89.36	0.00e+00	1960.00
IUUC-Aly-005768	Arabidopsis lyrata	35.03	4.00e-111	396.00
IUUC-Ath-006576	Arabidopsis thaliana	33.94	5.00e-111	395.00
IUUC-Ago-007748	Ashbya gossypii	41.61	4.00e-78	286.00
IUUC-Acl-008158	Aspergillus clavatus	38.17	2.00e-77	284.00
IUUC-Afl-008398	Aspergillus flavus	37.87	1.00e-77	285.00
IUUC-Afu-008937	Aspergillus fumigatus	39.07	2.00e-80	294.00
IUUC-Ani-009252	Aspergillus nidulans	38.38	3.00e-81	297.00
IUUC-Ang-009773	Aspergillus niger	34.08	2.00e-80	294.00
IUUC-Aor-009940	Aspergillus oryzae	37.87	1.00e-77	285.00
IUUC-Ate-010395	Aspergillus terreus	34.43	3.00e-80	293.00
IUUC-Ame-010769	Astyanax mexicanus	63.89	0.00e+00	1046.00
IUUC-Bgr-012269	Blumeria graminis	38.43	1.00e-76	280.00
IUUC-Bta-012841	Bos taurus	84.23	0.00e+00	1840.00
IUUC-Bci-013743	Botrytis cinerea	29.40	6.00e-86	312.00
IUUC-Bdi-014123	Brachypodium distachyon	47.06	2.00e-103	370.00
IUUC-Bol-015390	Brassica oleracea	34.05	4.00e-103	369.00
IUUC-Bra-016853	Brassica rapa	34.76	5.00e-110	392.00
IUUC-Cel-018638	Caenorhabditis elegans	39.86	2.00e-90	327.00
IUUC-Cja-019743	Callithrix jacchus	88.92	0.00e+00	1859.00
IUUC-Cfa-021031	Canis familiaris	86.93	0.00e+00	1891.00
IUUC-Cpo-022401	Cavia porcellus	85.20	0.00e+00	1866.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	8.00e-86	310.00
IUUC-Csa-024107	Chlorocebus sabaeus	87.32	0.00e+00	1909.00
IUUC-Cho-024750	Choloepus hoffmanni	82.08	0.00e+00	797.00
IUUC-Cin-025432	Ciona intestinalis	45.63	6.00e-99	354.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.84	5.00e-88	319.00
IUUC-Cne-026841	Cryptococcus neoformans	36.28	2.00e-94	340.00
IUUC-Cme-027265	Cyanidioschyzon merolae	46.62	7.00e-103	368.00
IUUC-Dre-028196	Danio rerio	76.24	0.00e+00	1594.00
IUUC-Dno-029024	Dasypus novemcinctus	88.39	0.00e+00	1931.00
IUUC-Dor-030483	Dipodomys ordii	89.03	0.00e+00	674.00
IUUC-Dse-031416	Dothistroma septosporum	34.76	1.00e-80	295.00
IUUC-Dme-031946	Drosophila melanogaster	36.18	0.00e+00	673.00
IUUC-Ete-032240	Echinops telfairi	81.01	2.00e-173	603.00
IUUC-Eca-033828	Equus caballus	90.96	0.00e+00	1899.00
IUUC-Eeu-034604	Erinaceus europaeus	84.23	2.00e-126	447.00
IUUC-Fca-035907	Felis catus	86.17	0.00e+00	1891.00
IUUC-Fal-037389	Ficedula albicollis	90.96	0.00e+00	2003.00
IUUC-Fox-037788	Fusarium oxysporum	37.79	4.00e-93	336.00
IUUC-Fso-038088	Fusarium solani	36.38	7.00e-90	325.00
IUUC-Gmo-039254	Gadus morhua	64.16	0.00e+00	1219.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.45	1.00e-83	304.00
IUUC-Gga-040310	Gallus gallus	90.16	0.00e+00	1982.00
IUUC-Gac-042054	Gasterosteus aculeatus	67.94	0.00e+00	1289.00
IUUC-Gma-042836	Glycine max	35.94	6.00e-102	365.00
IUUC-Ggo-045031	Gorilla gorilla	87.68	0.00e+00	1917.00
IUUC-Hsa-045880	Homo sapiens	87.59	0.00e+00	1915.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	80.61	0.00e+00	640.00
IUUC-Kpa-049307	Komagataella pastoris	36.99	1.00e-65	245.00
IUUC-Lch-050403	Latimeria chalumnae	80.56	0.00e+00	1699.00
IUUC-Loc-052218	Lepisosteus oculatus	80.09	0.00e+00	1711.00
IUUC-Lma-053096	Leptosphaeria maculans	38.79	3.00e-81	297.00
IUUC-Laf-054162	Loxodonta africana	87.69	0.00e+00	1649.00
IUUC-Mcc-055127	Macaca mulatta	87.41	0.00e+00	1910.00
IUUC-Meu-056187	Macropus eugenii	84.35	2.00e-108	387.00
IUUC-Mor-057021	Magnaporthe oryzae	34.03	6.00e-80	292.00
IUUC-Mpo-057570	Magnaporthe poae	36.46	4.00e-77	283.00
IUUC-Mtr-058154	Medicago truncatula	34.33	7.00e-105	375.00
IUUC-Mla-059124	Melampsora laricipopulina	48.03	5.00e-102	364.00
IUUC-Mga-059581	Meleagris gallopavo	90.20	0.00e+00	1972.00
IUUC-Mvi-060445	Microbotryum violaceum	38.36	1.00e-106	381.00
IUUC-Mmr-061360	Microcebus murinus	87.24	0.00e+00	1778.00
IUUC-Mmu-064189	Mus musculus	85.11	0.00e+00	1887.00
IUUC-Mac-065275	Musa acuminata	49.88	5.00e-110	392.00
IUUC-Mpu-066439	Mustela putorius furo	88.99	0.00e+00	1859.00
IUUC-Mlu-068228	Myotis lucifugus	87.49	0.00e+00	1836.00
IUUC-Nfi-068280	Neosartorya fischeri	39.07	9.00e-81	295.00
IUUC-Ncr-068869	Neurospora crassa	35.61	5.00e-84	306.00
IUUC-Nle-069687	Nomascus leucogenys	90.49	0.00e+00	1879.00
IUUC-Opr-070592	Ochotona princeps	96.00	2.00e-113	403.00
IUUC-Ont-071836	Oreochromis niloticus	76.60	0.00e+00	1650.00
IUUC-Oan-072800	Ornithorhynchus anatinus	91.31	0.00e+00	2003.00
IUUC-Ocu-074587	Oryctolagus cuniculus	88.21	0.00e+00	1926.00
IUUC-Ogl-077003	Oryza glaberrima	49.39	2.00e-108	387.00
IUUC-Ome-081342	Oryza meridionalis	46.40	1.00e-95	344.00
IUUC-Ola-087209	Oryzias latipes	75.98	0.00e+00	1611.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.59	1.00e-87	317.00
IUUC-Oga-088776	Otolemur garnettii	83.07	0.00e+00	1740.00
IUUC-Oar-089441	Ovis aries	83.45	0.00e+00	1819.00
IUUC-Ptr-091273	Pan troglodytes	87.50	0.00e+00	1913.00
IUUC-Pan-091981	Papio anubis	87.32	0.00e+00	1911.00
IUUC-Psi-093203	Pelodiscus sinensis	89.69	0.00e+00	1724.00
IUUC-Pma-094738	Petromyzon marinus	62.28	0.00e+00	1316.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.92	4.00e-58	219.00
IUUC-Ppa-095682	Physcomitrella patens	37.18	3.00e-113	403.00
IUUC-Pfo-097511	Poecilia formosa	76.86	0.00e+00	1660.00
IUUC-Pab-098634	Pongo abelii	84.59	0.00e+00	1831.00
IUUC-Pop-098928	Populus trichocarpa	34.64	3.00e-99	356.00
IUUC-Pca-100987	Procavia capensis	84.93	0.00e+00	857.00
IUUC-Ppe-102040	Prunus persica	42.06	7.00e-97	348.00
IUUC-Pva-103034	Pteropus vampyrus	84.56	0.00e+00	1745.00
IUUC-Pgr-103513	Puccinia graminis	39.41	9.00e-107	381.00
IUUC-Ptt-103967	Puccinia triticina	41.73	3.00e-95	343.00
IUUC-Pte-104105	Pyrenophora teres	38.15	2.00e-79	291.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.93	2.00e-79	290.00
IUUC-Rno-105380	Rattus norvegicus	85.00	0.00e+00	1632.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.77	1.00e-67	251.00
IUUC-Sha-107108	Sarcophilus harrisii	91.66	0.00e+00	1884.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.06	5.00e-96	346.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.36	2.00e-95	343.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	32.55	1.00e-82	301.00
IUUC-Smo-109537	Selaginella moellendorffii	36.83	1.00e-104	374.00
IUUC-Sit-110457	Setaria italica	49.02	5.00e-100	359.00
IUUC-Sly-111362	Solanum lycopersicum	35.57	5.00e-102	365.00
IUUC-Sar-113687	Sorex araneus	79.52	0.00e+00	894.00
IUUC-Sre-115038	Sporisorium reilianum	44.96	7.00e-99	355.00
IUUC-Ssc-115378	Sus scrofa	94.43	0.00e+00	746.00
IUUC-Tgu-116729	Taeniopygia guttata	90.43	0.00e+00	1984.00
IUUC-Tru-118068	Takifugu rubripes	74.91	0.00e+00	1607.00
IUUC-Tsy-118942	Tarsius syrichta	89.61	0.00e+00	701.00
IUUC-Tni-120732	Tetraodon nigroviridis	86.41	0.00e+00	1219.00
IUUC-Tca-121737	Theobroma cacao	35.39	4.00e-107	382.00
IUUC-Tre-121892	Trichoderma reesei	36.94	3.00e-88	320.00
IUUC-Tvi-122354	Trichoderma virens	36.20	1.00e-89	324.00
IUUC-Tme-127102	Tuber melanosporum	36.24	5.00e-94	339.00
IUUC-Tbe-127351	Tupaia belangeri	77.60	0.00e+00	1451.00
IUUC-Ttr-129061	Tursiops truncatus	83.42	0.00e+00	1794.00
IUUC-Uma-129343	Ustilago maydis	44.96	1.00e-99	358.00
IUUC-Vda-129748	Verticillium dahliae	38.82	1.00e-80	295.00
IUUC-Vvi-131234	Vitis vinifera	35.34	1.00e-104	374.00
IUUC-Xtr-132094	Xenopus tropicalis	84.69	0.00e+00	1843.00
IUUC-Xma-133923	Xiphophorus maculatus	77.13	0.00e+00	1663.00
IUUC-Yli-134496	Yarrowia lipolytica	37.18	2.00e-91	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence