iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049317

Ensembl Protein ID

CAY70982

UniProt Accession

C4R5Z6; C4R5Z6_KOMPG

Genbank Protein ID

CAY70982.1

Protein Name

Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway

Genbank Nucleotide ID

FN392321

Gene Name

PAS_chr3_0924

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr3_0924	CAY70982	CAY70982

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	9.60e-50	166.0	10	159

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eee 90
           Rl ke+++l++d pegi a+p de+dl+ we+li+Gp+dtpYe+gvF+++++fp+dYP++PPk+kf  ++ hPn+y++G+vC+sil+           +ee
   Q: 10   RLFKEYQQLSRDAPEGIIAGPLDEDDLFYWECLIEGPKDTPYENGVFSAQLTFPKDYPLSPPKLKFNPPLIHPNIYADGTVCISILHppgndpllyerPEE 110
           899***********************************************************************************889999999999*** PP
   S: 91   kWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           +Wsp++sve++lls+ s+laepn+es++n +++++++++r +++ +vre
   Q: 111  RWSPVQSVEKILLSVASMLAEPNVESGANIDVCKIWRDDRPKFDAMVRE 159
           *********************************************9985 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MPPKSTAQRR LFKEYQQLSR DAPEGIIAGP LDEDDLFYWE CLIEGPKDTP YENGVFSAQL 60
TFPKDYPLSP PKLKFNPPLI HPNIYADGTV CISILHPPGN DPLLYERPEE RWSPVQSVEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTCCCA AATCAACCGC TCAACGACGG TTATTCAAGG AATACCAGCA GCTATCCCGT 60
GATGCCCCTG AGGGGATAAT TGCGGGCCCT CTGGATGAAG ATGATTTGTT TTATTGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ppa:PAS_chr3_0924

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	36.36	7.00e-28	114.00
IUUC-Aml-002172	Ailuropoda melanoleuca	62.42	1.00e-55	206.00
IUUC-Atr-003150	Amborella trichopoda	54.05	7.00e-33	130.00
IUUC-Apl-003761	Anas platyrhynchos	62.03	1.00e-56	209.00
IUUC-Aca-005062	Anolis carolinensis	62.58	4.00e-58	214.00
IUUC-Aly-005452	Arabidopsis lyrata	51.02	2.00e-36	142.00
IUUC-Ath-007258	Arabidopsis thaliana	52.38	3.00e-37	145.00
IUUC-Ago-007853	Ashbya gossypii	69.75	3.00e-68	248.00
IUUC-Acl-008080	Aspergillus clavatus	63.41	4.00e-61	224.00
IUUC-Afl-008478	Aspergillus flavus	62.80	2.00e-60	222.00
IUUC-Afu-009051	Aspergillus fumigatus	64.02	2.00e-61	225.00
IUUC-Ani-009271	Aspergillus nidulans	63.03	7.00e-54	200.00
IUUC-Ang-009748	Aspergillus niger	63.41	7.00e-61	223.00
IUUC-Aor-010228	Aspergillus oryzae	62.80	2.00e-60	222.00
IUUC-Ate-010293	Aspergillus terreus	62.80	2.00e-60	222.00
IUUC-Ame-011698	Astyanax mexicanus	64.42	3.00e-61	224.00
IUUC-Bgr-012226	Blumeria graminis	61.59	1.00e-58	216.00
IUUC-Bta-013277	Bos taurus	67.48	7.00e-46	173.00
IUUC-Bci-013676	Botrytis cinerea	59.76	7.00e-57	210.00
IUUC-Bdi-014838	Brachypodium distachyon	50.00	2.00e-38	149.00
IUUC-Bol-016017	Brassica oleracea	55.32	2.00e-43	166.00
IUUC-Bra-017105	Brassica rapa	55.32	2.00e-43	166.00
IUUC-Cel-018676	Caenorhabditis elegans	62.11	3.00e-58	215.00
IUUC-Cja-019767	Callithrix jacchus	63.80	5.00e-60	220.00
IUUC-Cfa-020047	Canis familiaris	63.80	8.00e-60	220.00
IUUC-Cpo-021507	Cavia porcellus	63.80	1.00e-59	219.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	51.27	1.00e-40	156.00
IUUC-Csa-023745	Chlorocebus sabaeus	61.64	6.00e-56	207.00
IUUC-Cin-025310	Ciona intestinalis	63.19	6.00e-60	220.00
IUUC-Csv-025961	Ciona savignyi	61.35	1.00e-58	216.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	62.20	6.00e-59	217.00
IUUC-Cne-026903	Cryptococcus neoformans	60.61	1.00e-54	203.00
IUUC-Cme-027321	Cyanidioschyzon merolae	51.53	9.00e-38	147.00
IUUC-Dre-027900	Danio rerio	64.42	4.00e-61	224.00
IUUC-Dno-029688	Dasypus novemcinctus	63.40	1.00e-55	206.00
IUUC-Dor-030686	Dipodomys ordii	45.78	2.00e-37	146.00
IUUC-Dse-031253	Dothistroma septosporum	61.59	2.00e-59	219.00
IUUC-Dme-031849	Drosophila melanogaster	64.42	8.00e-61	223.00
IUUC-Ete-033010	Echinops telfairi	63.80	2.00e-58	215.00
IUUC-Eca-033294	Equus caballus	62.42	4.00e-56	207.00
IUUC-Eeu-034947	Erinaceus europaeus	55.12	4.00e-33	130.00
IUUC-Fca-036442	Felis catus	64.96	4.00e-50	187.00
IUUC-Fal-037188	Ficedula albicollis	62.75	8.00e-56	207.00
IUUC-Fox-037762	Fusarium oxysporum	63.19	2.00e-60	221.00
IUUC-Fso-038181	Fusarium solani	62.58	1.00e-59	219.00
IUUC-Gmo-038663	Gadus morhua	63.19	8.00e-60	220.00
IUUC-Ggr-039808	Gaeumannomyces graminis	60.98	7.00e-59	217.00
IUUC-Gga-040355	Gallus gallus	63.19	4.00e-60	221.00
IUUC-Gac-041847	Gasterosteus aculeatus	64.42	1.00e-60	223.00
IUUC-Gma-044131	Glycine max	52.38	4.00e-30	121.00
IUUC-Ggo-045202	Gorilla gorilla	63.80	6.00e-60	220.00
IUUC-Hsa-046369	Homo sapiens	63.80	6.00e-60	220.00
IUUC-Hvu-047065	Hordeum vulgare	48.99	1.00e-35	140.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	64.42	4.00e-60	221.00
IUUC-Lch-049596	Latimeria chalumnae	62.99	2.00e-55	206.00
IUUC-Lpe-050981	Leersia perrieri	53.19	9.00e-37	144.00
IUUC-Loc-052346	Lepisosteus oculatus	67.48	2.00e-46	174.00
IUUC-Lma-053126	Leptosphaeria maculans	62.88	3.00e-49	184.00
IUUC-Laf-054560	Loxodonta africana	61.11	1.00e-56	209.00
IUUC-Mcc-055172	Macaca mulatta	63.80	6.00e-60	220.00
IUUC-Meu-056891	Macropus eugenii	62.42	8.00e-56	206.00
IUUC-Mor-057260	Magnaporthe oryzae	60.37	7.00e-59	217.00
IUUC-Mpo-057468	Magnaporthe poae	60.98	5.00e-59	217.00
IUUC-Mtr-058406	Medicago truncatula	51.70	9.00e-38	147.00
IUUC-Mla-059084	Melampsora laricipopulina	59.06	5.00e-60	221.00
IUUC-Mga-059939	Meleagris gallopavo	61.39	1.00e-56	209.00
IUUC-Mvi-060514	Microbotryum violaceum	64.24	2.00e-62	229.00
IUUC-Mmr-061029	Microcebus murinus	61.45	9.00e-55	203.00
IUUC-Mdo-061820	Monodelphis domestica	63.80	4.00e-60	221.00
IUUC-Mmu-063123	Mus musculus	63.80	6.00e-60	220.00
IUUC-Mac-065294	Musa acuminata	48.99	3.00e-35	138.00
IUUC-Mpu-065866	Mustela putorius furo	61.49	1.00e-55	206.00
IUUC-Mlu-067220	Myotis lucifugus	62.42	7.00e-56	207.00
IUUC-Nfi-068395	Neosartorya fischeri	64.02	2.00e-61	225.00
IUUC-Ncr-068623	Neurospora crassa	61.35	1.00e-58	216.00
IUUC-Nle-070007	Nomascus leucogenys	63.80	6.00e-60	220.00
IUUC-Opr-070958	Ochotona princeps	56.76	3.00e-44	168.00
IUUC-Ont-071736	Oreochromis niloticus	63.80	9.00e-61	223.00
IUUC-Oan-073475	Ornithorhynchus anatinus	63.40	2.00e-55	205.00
IUUC-Ocu-074820	Oryctolagus cuniculus	65.13	1.00e-56	209.00
IUUC-Oba-075155	Oryza barthii	53.19	3.00e-36	142.00
IUUC-Obr-076863	Oryza brachyantha	52.48	5.00e-37	144.00
IUUC-Ogl-077935	Oryza glaberrima	53.19	3.00e-36	142.00
IUUC-Ogu-078510	Oryza glumaepatula	53.19	3.00e-36	142.00
IUUC-Oin-080104	Oryza indica	53.19	3.00e-36	142.00
IUUC-Olo-080294	Oryza longistaminata	53.19	3.00e-36	142.00
IUUC-Ome-081190	Oryza meridionalis	49.33	2.00e-38	149.00
IUUC-Oni-082689	Oryza nivara	53.19	3.00e-36	142.00
IUUC-Opu-083784	Oryza punctata	53.19	3.00e-36	142.00
IUUC-Oru-084660	Oryza rufipogon	53.19	3.00e-36	142.00
IUUC-Osa-086247	Oryza sativa	53.19	3.00e-36	142.00
IUUC-Ola-087571	Oryzias latipes	63.19	3.00e-60	221.00
IUUC-Olu-087887	Ostreococcus lucimarinus	54.55	5.00e-46	174.00
IUUC-Oga-088473	Otolemur garnettii	54.84	4.00e-45	171.00
IUUC-Oar-089706	Ovis aries	63.80	7.00e-60	220.00
IUUC-Ptr-090798	Pan troglodytes	63.80	6.00e-60	220.00
IUUC-Pan-091967	Papio anubis	63.80	6.00e-60	220.00
IUUC-Psi-093524	Pelodiscus sinensis	63.58	4.00e-55	204.00
IUUC-Pma-094602	Petromyzon marinus	66.19	6.00e-52	193.00
IUUC-Pno-094979	Phaeosphaeria nodorum	64.42	3.00e-63	231.00
IUUC-Ppa-095965	Physcomitrella patens	49.69	2.00e-43	166.00
IUUC-Pfo-097330	Poecilia formosa	63.80	6.00e-60	220.00
IUUC-Pab-098225	Pongo abelii	63.19	3.00e-59	218.00
IUUC-Pop-099881	Populus trichocarpa	51.30	8.00e-40	154.00
IUUC-Pca-101040	Procavia capensis	63.40	2.00e-55	205.00
IUUC-Ppe-101778	Prunus persica	52.38	2.00e-36	142.00
IUUC-Pva-103074	Pteropus vampyrus	58.45	1.00e-43	167.00
IUUC-Pgr-103674	Puccinia graminis	61.18	3.00e-59	218.00
IUUC-Ptt-103840	Puccinia triticina	60.00	8.00e-59	217.00
IUUC-Pte-104389	Pyrenophora teres	63.80	8.00e-63	230.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	64.42	1.00e-62	229.00
IUUC-Rno-105228	Rattus norvegicus	63.80	6.00e-60	220.00
IUUC-Sce-106233	Saccharomyces cerevisiae	67.28	3.00e-65	238.00
IUUC-Sha-107274	Sarcophilus harrisii	63.92	6.00e-56	207.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	65.85	3.00e-64	234.00
IUUC-Spo-108269	Schizosaccharomyces pombe	64.02	3.00e-62	228.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	60.37	2.00e-58	215.00
IUUC-Smo-109401	Selaginella moellendorffii	50.00	1.00e-31	126.00
IUUC-Sit-110784	Setaria italica	53.19	2.00e-36	142.00
IUUC-Sly-111843	Solanum lycopersicum	51.25	1.00e-38	149.00
IUUC-Stu-112654	Solanum tuberosum	53.90	3.00e-37	145.00
IUUC-Sar-112992	Sorex araneus	48.30	3.00e-33	132.00
IUUC-Sbi-113787	Sorghum bicolor	49.38	1.00e-37	146.00
IUUC-Sre-114952	Sporisorium reilianum	60.24	2.00e-57	212.00
IUUC-Ssc-115365	Sus scrofa	62.58	6.00e-56	207.00
IUUC-Tgu-116816	Taeniopygia guttata	63.19	4.00e-60	221.00
IUUC-Tru-118443	Takifugu rubripes	53.90	3.00e-45	171.00
IUUC-Tsy-119168	Tarsius syrichta	58.45	1.00e-43	167.00
IUUC-Tni-120278	Tetraodon nigroviridis	63.41	1.00e-58	216.00
IUUC-Tca-121649	Theobroma cacao	47.92	4.00e-33	131.00
IUUC-Tre-122131	Trichoderma reesei	60.98	4.00e-59	218.00
IUUC-Tvi-122669	Trichoderma virens	61.59	7.00e-60	220.00
IUUC-Tae-123772	Triticum aestivum	50.00	4.00e-39	151.00
IUUC-Tur-126873	Triticum urartu	49.67	2.00e-36	144.00
IUUC-Tme-127052	Tuber melanosporum	65.03	2.00e-63	232.00
IUUC-Tbe-127792	Tupaia belangeri	63.80	6.00e-60	220.00
IUUC-Ttr-128609	Tursiops truncatus	58.45	1.00e-43	167.00
IUUC-Uma-129587	Ustilago maydis	59.64	3.00e-57	211.00
IUUC-Vda-129914	Verticillium dahliae	59.76	8.00e-58	213.00
IUUC-Vpa-130208	Vicugna pacos	56.76	2.00e-44	169.00
IUUC-Vvi-131387	Vitis vinifera	52.38	3.00e-36	142.00
IUUC-Xtr-132450	Xenopus tropicalis	63.80	2.00e-60	222.00
IUUC-Xma-133016	Xiphophorus maculatus	63.80	8.00e-60	220.00
IUUC-Yli-134379	Yarrowia lipolytica	66.87	2.00e-63	232.00
IUUC-Zma-135806	Zea mays	50.00	3.00e-39	152.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence