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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063761
UUCD1 version UUC-MuM-00244
Ensembl Protein ID ENSMUSP00000080813.5
UniProt Accession G3X9I6; G3X9I6_MOUSE
Genbank Protein ID EDL16619.1
Protein Name E3 ubiquitin-protein ligase TRIM68; Tripartite motif containing 68
Genbank Nucleotide ID AC161431
Gene Name Trim68; mCG_23411
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000073968.4 ENSMUST00000082175.6 ENSMUSP00000080813.5
ENSMUSG00000073968.4 ENSMUST00000210855.1 ENSMUSP00000147991.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/U-box 2.90e-07 31.6 10 80
E3 activity/RING/RING 7.70e-10 40.3 16 61
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl.asggk.....tcPvtrqplteedlvPnltlrrliq 66
           + ee +CpI ++  r+Pv +++G+t+  s++       g++     tcP++r+p+++++l Pn  l ++++
   Q: 10   IVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWkLPGESqnlsyTCPLCRAPVKPRKLRPNWQLASVVD 80
           67999**************************985524444477899*****************99988776 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC++ +++ p++ +CgH+f+++Cl   w+++  s++ + +CPlCr
   Q: 16   CPICMTFLRE-PVSISCGHTFCHSCLsGLWKLPGESQNLSYTCPLCR 61
           ********88.***************88887777779*********8 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDPAVLMEAI VEEVNCPICM TFLREPVSIS CGHTFCHSCL SGLWKLPGES QNLSYTCPLC 60
RAPVKPRKLR PNWQLASVVD KVRLLGFCME MGLKTDVCDL HKEQLTMFCK EDDMVTCEAC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063761|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGTGGGTCC TGCAGCTCCG GGCGCGGCTC TTGCCTTGGG TCCCTCGCCC CCGCTGCTAT 60
CGCGGCTTCC GGCGGCGGGC GAGCGCCCCG CTGCTTCCTA CGCTGCGGAT TGGACCGCTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063761|E3,U-box;E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PRINTS

PR01407--BUTYPHLNCDUF
SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005730--C:nucleolus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
GO:0060765--P:regulation of androgen receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002078 Ailuropoda melanoleuca 78.93 0.00e+00 728.00
IUUC-Acl-008377 Aspergillus clavatus 43.94 2.00e-09 57.00
IUUC-Ang-009514 Aspergillus niger 35.56 7.00e-09 55.50
IUUC-Bta-012800 Bos taurus 73.61 0.00e+00 748.00
IUUC-Cja-019382 Callithrix jacchus 76.45 0.00e+00 714.00
IUUC-Cfa-020686 Canis familiaris 77.11 5.00e-153 533.00
IUUC-Csa-023952 Chlorocebus sabaeus 78.10 0.00e+00 714.00
IUUC-Cho-024811 Choloepus hoffmanni 72.73 0.00e+00 637.00
IUUC-Dno-029361 Dasypus novemcinctus 77.07 0.00e+00 721.00
IUUC-Dor-030703 Dipodomys ordii 77.07 0.00e+00 718.00
IUUC-Dse-031398 Dothistroma septosporum 44.07 5.00e-09 56.20
IUUC-Ete-033159 Echinops telfairi 84.19 1.00e-110 393.00
IUUC-Eca-033633 Equus caballus 73.49 0.00e+00 653.00
IUUC-Eeu-034686 Erinaceus europaeus 68.25 0.00e+00 649.00
IUUC-Fca-035750 Felis catus 77.87 0.00e+00 730.00
IUUC-Ggo-045524 Gorilla gorilla 78.31 0.00e+00 721.00
IUUC-Hsa-046031 Homo sapiens 78.10 0.00e+00 741.00
IUUC-Itr-048898 Ictidomys tridecemlineatus 76.86 0.00e+00 710.00
IUUC-Laf-054264 Loxodonta africana 75.78 0.00e+00 750.00
IUUC-Mcc-055388 Macaca mulatta 78.10 0.00e+00 714.00
IUUC-Mmr-060612 Microcebus murinus 72.77 0.00e+00 666.00
IUUC-Mpu-066319 Mustela putorius furo 79.13 0.00e+00 737.00
IUUC-Mlu-067368 Myotis lucifugus 76.86 0.00e+00 705.00
IUUC-Nle-069702 Nomascus leucogenys 78.10 0.00e+00 720.00
IUUC-Opr-070810 Ochotona princeps 68.68 1.00e-175 609.00
IUUC-Ont-072259 Oreochromis niloticus 34.42 8.00e-70 258.00
IUUC-Oga-088935 Otolemur garnettii 74.38 0.00e+00 686.00
IUUC-Oar-089940 Ovis aries 78.93 0.00e+00 734.00
IUUC-Ptr-091056 Pan troglodytes 78.10 0.00e+00 721.00
IUUC-Pan-092165 Papio anubis 78.10 0.00e+00 714.00
IUUC-Pab-098415 Pongo abelii 79.08 3.00e-139 487.00
IUUC-Pca-100470 Procavia capensis 71.13 0.00e+00 698.00
IUUC-Pva-102603 Pteropus vampyrus 73.35 0.00e+00 657.00
IUUC-Rno-105709 Rattus norvegicus 89.34 0.00e+00 835.00
IUUC-Sar-113101 Sorex araneus 74.93 2.00e-138 484.00
IUUC-Ssc-115920 Sus scrofa 76.86 0.00e+00 716.00
IUUC-Tbe-127512 Tupaia belangeri 70.47 1.00e-146 512.00
Created Date 25-Jun-2017

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