iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040426

Ensembl Protein ID

ENSGALP00000001688.1

UniProt Accession

Q8AXV0; SH3G1_CHICK

Genbank Protein ID

CAD27936.1

Protein Name

Endophilin-A2; Endophilin-2; SH3 domain-containing GRB2-like protein 2; SH3p8

Genbank Nucleotide ID

AJ439351

Gene Name

SH3GL1; SH3P8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000001121.5	ENSGALT00000001690.2	ENSGALP00000001688.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.20e-16	58.3	309	362

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +++lyd+e++nd+eL +k+Gd++++   ++ de+W +g    +g++G+fP n+ve l
   Q: 309  CCKALYDFEPENDGELGFKEGDIITLT--NQIDENWYEG--MINGQSGFFPLNYVEVL 362
           599***********************7..99********..8*************976 PP

Organism

Gallus gallus

Functional Description
(View)

Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

Protein Sequence
(Fasta)

MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFKEMEKKV DLTSKAVTEV LTRTIEYLQP 60
NPASRAKLTM LNTMSKIRGQ VKNPGYPQSE GLLGESMIRY GKELGEDSNF GDALLDAGES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGAAACGG CGTCGGTTCA GCGGCCGAGC GGGCTGCGGG TGGGCTCCGT GTTTGCCGAG 60
TGTCACCGCG GCGTCCCGCC GCCCGCTGCG CGTCCCCAGG CGGCCGGCCG GCACAGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0030054--C:cell junction
GO:0042995--C:cell projection
GO:0031901--C:early endosome membrane
GO:0002102--C:podosome
GO:0045202--C:synapse
GO:0008289--F:lipid binding
GO:0016191--P:synaptic vesicle uncoating

KEGG

gga:395202

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001620	Ailuropoda melanoleuca	88.33	2.00e-179	620.00
IUUC-Apl-004209	Anas platyrhynchos	98.31	0.00e+00	667.00
IUUC-Ame-011047	Astyanax mexicanus	75.61	2.00e-157	547.00
IUUC-Bta-012875	Bos taurus	91.30	0.00e+00	688.00
IUUC-Cin-025799	Ciona intestinalis	50.95	1.00e-103	369.00
IUUC-Csv-026266	Ciona savignyi	52.08	2.00e-102	365.00
IUUC-Cne-027089	Cryptococcus neoformans	25.82	2.00e-08	53.90
IUUC-Dre-027986	Danio rerio	75.54	1.00e-159	555.00
IUUC-Dno-029193	Dasypus novemcinctus	89.13	0.00e+00	647.00
IUUC-Dor-030288	Dipodomys ordii	80.16	3.00e-161	560.00
IUUC-Eca-033277	Equus caballus	89.83	2.00e-175	607.00
IUUC-Fal-036965	Ficedula albicollis	95.66	0.00e+00	673.00
IUUC-Gmo-039523	Gadus morhua	74.86	6.00e-157	546.00
IUUC-Gac-042642	Gasterosteus aculeatus	77.11	8.00e-164	569.00
IUUC-Ggo-045448	Gorilla gorilla	91.30	0.00e+00	661.00
IUUC-Hsa-046112	Homo sapiens	91.30	0.00e+00	662.00
IUUC-Itr-048752	Ictidomys tridecemlineatus	90.22	0.00e+00	655.00
IUUC-Lch-050334	Latimeria chalumnae	68.98	4.00e-137	480.00
IUUC-Loc-052447	Lepisosteus oculatus	79.09	3.00e-175	607.00
IUUC-Laf-053698	Loxodonta africana	91.58	0.00e+00	691.00
IUUC-Mcc-055547	Macaca mulatta	86.96	2.00e-171	594.00
IUUC-Meu-056398	Macropus eugenii	78.53	3.00e-167	580.00
IUUC-Mga-060168	Meleagris gallopavo	97.18	0.00e+00	667.00
IUUC-Mmr-061056	Microcebus murinus	89.67	0.00e+00	652.00
IUUC-Mmu-063596	Mus musculus	88.04	0.00e+00	645.00
IUUC-Mpu-066681	Mustela putorius furo	89.67	0.00e+00	650.00
IUUC-Mlu-068113	Myotis lucifugus	85.39	7.00e-177	612.00
IUUC-Nle-070104	Nomascus leucogenys	89.19	3.00e-168	583.00
IUUC-Opr-070661	Ochotona princeps	89.46	0.00e+00	648.00
IUUC-Ont-071922	Oreochromis niloticus	77.11	5.00e-162	563.00
IUUC-Ola-086645	Oryzias latipes	77.90	9.00e-174	602.00
IUUC-Oga-088627	Otolemur garnettii	88.70	0.00e+00	652.00
IUUC-Pan-092433	Papio anubis	90.22	7.00e-178	615.00
IUUC-Psi-092940	Pelodiscus sinensis	93.85	0.00e+00	696.00
IUUC-Pma-094657	Petromyzon marinus	64.43	2.00e-126	445.00
IUUC-Ppa-095161	Physcomitrella patens	27.42	3.00e-10	59.30
IUUC-Pfo-096876	Poecilia formosa	76.29	2.00e-161	561.00
IUUC-Pab-097667	Pongo abelii	78.47	3.00e-149	520.00
IUUC-Pca-100102	Procavia capensis	83.97	6.00e-180	622.00
IUUC-Pva-102731	Pteropus vampyrus	82.07	6.00e-165	573.00
IUUC-Pgr-103312	Puccinia graminis	25.32	6.00e-15	75.50
IUUC-Rno-105425	Rattus norvegicus	88.04	0.00e+00	642.00
IUUC-Sha-106675	Sarcophilus harrisii	90.63	0.00e+00	674.00
IUUC-Sja-107704	Schizosaccharomyces japonicus	24.09	1.00e-13	70.90
IUUC-Spo-108224	Schizosaccharomyces pombe	24.93	1.00e-21	97.40
IUUC-Ssc-115548	Sus scrofa	90.79	0.00e+00	640.00
IUUC-Tru-117979	Takifugu rubripes	77.38	1.00e-163	568.00
IUUC-Tni-120585	Tetraodon nigroviridis	76.84	2.00e-161	561.00
IUUC-Ttr-128449	Tursiops truncatus	90.40	3.00e-176	610.00
IUUC-Xtr-131935	Xenopus tropicalis	85.29	5.00e-172	596.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence