iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-107526

Ensembl Protein ID

ENSSHAP00000005630.1

UniProt Accession

G3VR25; G3VR25_SARHA

Genbank Protein ID

ENSSHAP00000005630

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01222908

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004920.1	ENSSHAT00000005684.1	ENSSHAP00000005630.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.70e-09	36.3	3	42
ULD/UDP/UFD/UBX	4.60e-21	75.3	209	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +  +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 3    ERTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           55789********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++l+  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 209  EYDQCRIQVRLPDGTSLTQTFKAREQLAAVRLYVElhrgEELGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 290
           578*****************************************************************************98 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAERTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PPASPLGHSL 60
GHEPPSYGGG SPEGSGSAQV EEKPPLSEEE KREQTKRMLE LVAQKQKERG EREQREAVER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC GAACAGCTCT GGAGAGCCTC ATCGAGATGG GCTTCCCGCG GGGGCGCGCG 60
TAAGGAAACC CGTCCCCGCC CCCGGCTTTG CGGAACGTCC CCCGCTCTTT CCGCCCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

KEGG

shr:100913548

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	87.67	1.00e-96	345.00
IUUC-Atr-002867	Amborella trichopoda	33.33	5.00e-09	55.80
IUUC-Aca-004329	Anolis carolinensis	70.83	2.00e-49	187.00
IUUC-Ago-007989	Ashbya gossypii	37.18	6.00e-07	47.80
IUUC-Ate-010522	Aspergillus terreus	31.52	5.00e-03	35.40
IUUC-Ame-011399	Astyanax mexicanus	53.27	2.00e-60	225.00
IUUC-Bgr-012034	Blumeria graminis	31.39	2.00e-08	53.10
IUUC-Bta-013151	Bos taurus	87.12	3.00e-109	387.00
IUUC-Bol-015175	Brassica oleracea	31.88	5.00e-04	38.50
IUUC-Cel-018300	Caenorhabditis elegans	35.11	2.00e-13	69.30
IUUC-Cja-019084	Callithrix jacchus	86.97	1.00e-86	312.00
IUUC-Cfa-020997	Canis familiaris	84.45	7.00e-83	300.00
IUUC-Cpo-021736	Cavia porcellus	78.45	7.00e-78	283.00
IUUC-Csa-024040	Chlorocebus sabaeus	83.16	6.00e-94	336.00
IUUC-Cho-024543	Choloepus hoffmanni	89.55	2.00e-68	251.00
IUUC-Cin-025719	Ciona intestinalis	38.91	4.00e-35	141.00
IUUC-Csv-025854	Ciona savignyi	37.79	6.00e-36	144.00
IUUC-Cgl-026704	Colletotrichum gloeosporioides	42.50	1.00e-04	40.40
IUUC-Cne-027046	Cryptococcus neoformans	39.51	2.00e-09	56.20
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.40
IUUC-Dre-027745	Danio rerio	51.84	6.00e-59	220.00
IUUC-Dno-029598	Dasypus novemcinctus	85.14	3.00e-97	347.00
IUUC-Dor-030917	Dipodomys ordii	70.77	3.00e-75	274.00
IUUC-Dme-032055	Drosophila melanogaster	41.82	6.00e-23	101.00
IUUC-Ete-032960	Echinops telfairi	72.24	5.00e-72	264.00
IUUC-Eca-034294	Equus caballus	88.22	4.00e-107	380.00
IUUC-Eeu-034906	Erinaceus europaeus	84.91	9.00e-98	349.00
IUUC-Fca-035653	Felis catus	85.87	1.00e-87	316.00
IUUC-Gmo-038755	Gadus morhua	49.84	1.00e-53	203.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.04	2.00e-55	208.00
IUUC-Ggo-044821	Gorilla gorilla	82.39	4.00e-88	317.00
IUUC-Hsa-046797	Homo sapiens	88.55	2.00e-97	348.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	86.53	9.00e-98	349.00
IUUC-Lch-049508	Latimeria chalumnae	50.91	3.00e-54	204.00
IUUC-Laf-053932	Loxodonta africana	87.88	2.00e-114	404.00
IUUC-Mcc-055300	Macaca mulatta	83.16	5.00e-94	337.00
IUUC-Mor-056927	Magnaporthe oryzae	36.59	7.00e-07	47.80
IUUC-Mpo-057443	Magnaporthe poae	34.88	4.00e-06	45.10
IUUC-Mla-059083	Melampsora laricipopulina	30.30	5.00e-07	48.10
IUUC-Mvi-060245	Microbotryum violaceum	42.17	2.00e-11	63.20
IUUC-Mmr-060979	Microcebus murinus	76.43	2.00e-91	328.00
IUUC-Mdo-062299	Monodelphis domestica	97.88	3.00e-112	397.00
IUUC-Mmu-063212	Mus musculus	85.19	1.00e-103	369.00
IUUC-Mpu-066540	Mustela putorius furo	88.18	3.00e-99	354.00
IUUC-Mlu-067589	Myotis lucifugus	85.81	7.00e-99	353.00
IUUC-Nle-069045	Nomascus leucogenys	86.29	1.00e-67	249.00
IUUC-Opr-070772	Ochotona princeps	82.98	1.00e-81	296.00
IUUC-Ont-072006	Oreochromis niloticus	52.87	2.00e-56	212.00
IUUC-Oan-073244	Ornithorhynchus anatinus	64.21	3.00e-47	181.00
IUUC-Ocu-074333	Oryctolagus cuniculus	87.21	4.00e-96	344.00
IUUC-Ola-086781	Oryzias latipes	53.72	2.00e-53	202.00
IUUC-Oga-088429	Otolemur garnettii	87.21	2.00e-93	335.00
IUUC-Oar-089885	Ovis aries	87.46	2.00e-110	391.00
IUUC-Ptr-091315	Pan troglodytes	87.99	2.00e-89	322.00
IUUC-Pan-092885	Papio anubis	83.16	6.00e-94	336.00
IUUC-Psi-093299	Pelodiscus sinensis	71.49	6.00e-64	236.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Pno-094799	Phaeosphaeria nodorum	56.82	1.00e-06	47.00
IUUC-Pfo-096188	Poecilia formosa	54.25	6.00e-55	207.00
IUUC-Pab-097881	Pongo abelii	81.82	3.00e-92	331.00
IUUC-Pca-100977	Procavia capensis	85.02	1.00e-97	349.00
IUUC-Ppe-101615	Prunus persica	32.05	2.00e-07	50.40
IUUC-Pva-102169	Pteropus vampyrus	86.97	4.00e-90	324.00
IUUC-Pgr-103638	Puccinia graminis	43.59	5.00e-06	45.10
IUUC-Pte-104060	Pyrenophora teres	52.27	5.00e-06	45.10
IUUC-Pyt-104440	Pyrenophora triticirepentis	27.89	2.00e-06	46.60
IUUC-Rno-105459	Rattus norvegicus	85.19	1.00e-103	369.00
IUUC-Sce-106285	Saccharomyces cerevisiae	31.65	3.00e-06	46.20
IUUC-Sja-107741	Schizosaccharomyces japonicus	33.75	1.00e-06	46.60
IUUC-Ssl-108389	Sclerotinia sclerotiorum	28.26	3.00e-08	53.10
IUUC-Sit-109986	Setaria italica	32.10	4.00e-06	45.80
IUUC-Sly-111129	Solanum lycopersicum	32.93	4.00e-08	52.40
IUUC-Sar-112945	Sorex araneus	85.28	3.00e-66	244.00
IUUC-Sre-115055	Sporisorium reilianum	34.15	5.00e-06	45.10
IUUC-Ssc-116114	Sus scrofa	84.85	5.00e-96	343.00
IUUC-Tru-117839	Takifugu rubripes	53.40	9.00e-56	210.00
IUUC-Tsy-118813	Tarsius syrichta	64.79	3.00e-86	311.00
IUUC-Tni-120504	Tetraodon nigroviridis	57.09	1.00e-55	209.00
IUUC-Tvi-122638	Trichoderma virens	31.72	4.00e-09	55.80
IUUC-Tbe-128034	Tupaia belangeri	86.62	4.00e-89	321.00
IUUC-Ttr-128468	Tursiops truncatus	85.21	7.00e-92	330.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vda-129928	Verticillium dahliae	33.01	2.00e-06	46.60
IUUC-Vpa-130179	Vicugna pacos	82.25	2.00e-64	238.00
IUUC-Xtr-132119	Xenopus tropicalis	63.42	2.00e-66	245.00
IUUC-Xma-134067	Xiphophorus maculatus	53.23	9.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence