iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000012096.2	ENSSTOT00000012101.2	ENSSTOP00000010851.2
ENSSTOG00000012096.2	ENSSTOT00000024412.1	ENSSTOP00000017775.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	31.65	2.30e-02	35.40	IUUC-Sce-106169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

EAKYLCSACR NVLRRPFQAQ CGHRYCSFCL TSILSKLNVL CPSTKFLCFE TKAFPDNAAR 60
REVESLPAVC PNDGCTWKGT LKEYESCHEG LCPFLLTECP ACKGLVRLGE KERHVEQECP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAAGCTAG AGGCCAAGTA TTTGTGCTCT GCCTGCAGAA ATGTCCTACG GAGGCCCTTC 60
CAGGCCCAGT GTGGCCATCG CTATTGCTCA TTCTGTCTAA CCAGCATCCT CAGGTGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	72.22	0.00e+00	751.00
IUUC-Apl-004202	Anas platyrhynchos	64.91	0.00e+00	705.00
IUUC-Ame-011841	Astyanax mexicanus	50.42	5.00e-162	564.00
IUUC-Bta-013180	Bos taurus	71.67	0.00e+00	746.00
IUUC-Cja-019813	Callithrix jacchus	76.25	0.00e+00	802.00
IUUC-Cfa-021205	Canis familiaris	72.90	0.00e+00	764.00
IUUC-Cpo-021346	Cavia porcellus	79.34	0.00e+00	808.00
IUUC-Csa-023809	Chlorocebus sabaeus	79.08	0.00e+00	744.00
IUUC-Dre-027669	Danio rerio	52.23	2.00e-158	552.00
IUUC-Dno-029458	Dasypus novemcinctus	69.48	0.00e+00	739.00
IUUC-Dor-030338	Dipodomys ordii	75.10	0.00e+00	711.00
IUUC-Eca-034401	Equus caballus	74.33	0.00e+00	779.00
IUUC-Eeu-034668	Erinaceus europaeus	72.08	2.00e-76	279.00
IUUC-Fca-036057	Felis catus	72.41	0.00e+00	772.00
IUUC-Fal-037560	Ficedula albicollis	63.24	1.00e-177	615.00
IUUC-Gmo-038964	Gadus morhua	55.77	1.00e-167	582.00
IUUC-Gga-040425	Gallus gallus	64.71	0.00e+00	696.00
IUUC-Gac-041908	Gasterosteus aculeatus	57.20	3.00e-169	587.00
IUUC-Gma-043859	Glycine max	33.64	4.00e-06	47.80
IUUC-Ggo-044606	Gorilla gorilla	69.31	0.00e+00	710.00
IUUC-Hsa-046952	Homo sapiens	76.25	0.00e+00	801.00
IUUC-Lch-049571	Latimeria chalumnae	54.59	0.00e+00	627.00
IUUC-Loc-051973	Lepisosteus oculatus	57.36	3.00e-165	574.00
IUUC-Laf-053815	Loxodonta africana	70.91	0.00e+00	712.00
IUUC-Mcc-054888	Macaca mulatta	76.45	0.00e+00	799.00
IUUC-Meu-056547	Macropus eugenii	63.18	1.00e-167	582.00
IUUC-Mga-059819	Meleagris gallopavo	64.62	0.00e+00	665.00
IUUC-Mdo-062570	Monodelphis domestica	68.98	0.00e+00	716.00
IUUC-Mmu-063133	Mus musculus	77.80	0.00e+00	780.00
IUUC-Mpu-065802	Mustela putorius furo	72.34	0.00e+00	771.00
IUUC-Nle-070155	Nomascus leucogenys	76.83	0.00e+00	808.00
IUUC-Opr-070856	Ochotona princeps	67.03	9.00e-102	363.00
IUUC-Ont-071930	Oreochromis niloticus	57.63	1.00e-179	622.00
IUUC-Ola-087397	Oryzias latipes	54.51	5.00e-173	600.00
IUUC-Oga-088109	Otolemur garnettii	75.87	0.00e+00	799.00
IUUC-Oar-090310	Ovis aries	66.54	0.00e+00	659.00
IUUC-Ptr-090643	Pan troglodytes	76.64	0.00e+00	805.00
IUUC-Pan-091933	Papio anubis	76.64	0.00e+00	800.00
IUUC-Psi-093681	Pelodiscus sinensis	63.00	0.00e+00	662.00
IUUC-Pfo-096148	Poecilia formosa	54.69	3.00e-175	607.00
IUUC-Pab-098631	Pongo abelii	76.64	0.00e+00	808.00
IUUC-Pca-100582	Procavia capensis	55.12	1.00e-79	290.00
IUUC-Pva-102396	Pteropus vampyrus	69.18	9.00e-112	397.00
IUUC-Rno-106120	Rattus norvegicus	76.45	0.00e+00	756.00
IUUC-Sce-106169	Saccharomyces cerevisiae	31.65	8.00e-03	35.40
IUUC-Sha-106493	Sarcophilus harrisii	69.36	0.00e+00	739.00
IUUC-Sar-113570	Sorex araneus	93.92	2.00e-100	358.00
IUUC-Ssc-115843	Sus scrofa	70.76	0.00e+00	761.00
IUUC-Tgu-117144	Taeniopygia guttata	60.38	6.00e-168	583.00
IUUC-Tru-117853	Takifugu rubripes	55.13	4.00e-175	607.00
IUUC-Tni-120256	Tetraodon nigroviridis	58.30	0.00e+00	628.00
IUUC-Ttr-129246	Tursiops truncatus	74.66	0.00e+00	752.00
IUUC-Xtr-132279	Xenopus tropicalis	52.90	2.00e-145	508.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence