iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066291

Ensembl Protein ID

ENSMPUP00000016091.1

UniProt Accession

M3YXN1; M3YXN1_MUSPF

Genbank Protein ID

ENSMPUP00000016091

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01053473

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016195.1	ENSMPUT00000016335.1	ENSMPUP00000016091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	9.50e-19	67.1	27	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 27   DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 61
           79*******************************86 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

LQHDLLIYLI SRKKMSLKSE RRGIHVDQSE LLCKKGCGYY GNPAWQGFCS KCWREEYHKA 60
RQKQIQEDWE LAERLQREEE EAFASSQSSQ GAQSLTFSKF EEKKTNEKTR KVTTVKKFFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAACATG ACCTTCTTAT TTATTTGATT AGCAGGAAGA AGATGAGCCT TAAGTCTGAA 60
CGCCGAGGGA TTCATGTGGA TCAGTCCGAG CTCCTGTGCA AGAAAGGATG TGGTTACTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	32.26	2.00e-20	93.60
IUUC-Aml-001771	Ailuropoda melanoleuca	89.15	0.00e+00	766.00
IUUC-Atr-003154	Amborella trichopoda	36.52	5.00e-23	102.00
IUUC-Apl-004018	Anas platyrhynchos	91.28	0.00e+00	838.00
IUUC-Aca-005227	Anolis carolinensis	23.98	1.00e-09	58.50
IUUC-Aly-006138	Arabidopsis lyrata	35.45	8.00e-25	108.00
IUUC-Ath-006929	Arabidopsis thaliana	33.33	4.00e-26	112.00
IUUC-Ago-007776	Ashbya gossypii	29.75	2.00e-23	103.00
IUUC-Acl-008235	Aspergillus clavatus	30.74	2.00e-28	121.00
IUUC-Afl-008570	Aspergillus flavus	31.54	4.00e-31	129.00
IUUC-Afu-008815	Aspergillus fumigatus	30.53	5.00e-29	122.00
IUUC-Ani-009381	Aspergillus nidulans	30.04	3.00e-29	123.00
IUUC-Ang-009615	Aspergillus niger	28.74	3.00e-31	129.00
IUUC-Aor-010195	Aspergillus oryzae	31.54	1.00e-31	131.00
IUUC-Ate-010514	Aspergillus terreus	31.10	1.00e-29	124.00
IUUC-Ame-011365	Astyanax mexicanus	66.01	0.00e+00	662.00
IUUC-Bgr-012102	Blumeria graminis	28.53	2.00e-29	124.00
IUUC-Bta-013124	Bos taurus	96.95	0.00e+00	881.00
IUUC-Bci-013943	Botrytis cinerea	29.79	1.00e-29	125.00
IUUC-Bdi-014539	Brachypodium distachyon	30.95	1.00e-26	114.00
IUUC-Bol-016580	Brassica oleracea	35.43	8.00e-30	124.00
IUUC-Bra-017843	Brassica rapa	34.98	1.00e-29	124.00
IUUC-Cel-018199	Caenorhabditis elegans	33.59	2.00e-58	219.00
IUUC-Cja-019941	Callithrix jacchus	95.78	0.00e+00	883.00
IUUC-Cfa-020845	Canis familiaris	98.04	0.00e+00	824.00
IUUC-Cpo-022037	Cavia porcellus	96.54	0.00e+00	872.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.47	3.00e-20	93.20
IUUC-Csa-023495	Chlorocebus sabaeus	95.76	0.00e+00	880.00
IUUC-Cho-025076	Choloepus hoffmanni	84.76	0.00e+00	731.00
IUUC-Cin-025400	Ciona intestinalis	44.36	4.00e-115	408.00
IUUC-Csv-025941	Ciona savignyi	38.38	4.00e-87	315.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	28.72	7.00e-27	115.00
IUUC-Cne-027057	Cryptococcus neoformans	33.46	2.00e-34	140.00
IUUC-Dre-028484	Danio rerio	70.95	0.00e+00	667.00
IUUC-Dno-028906	Dasypus novemcinctus	96.75	0.00e+00	872.00
IUUC-Dor-030124	Dipodomys ordii	85.95	0.00e+00	748.00
IUUC-Dse-031437	Dothistroma septosporum	27.96	1.00e-25	112.00
IUUC-Dme-031696	Drosophila melanogaster	32.71	3.00e-69	256.00
IUUC-Ete-032573	Echinops telfairi	92.00	0.00e+00	716.00
IUUC-Eca-033711	Equus caballus	97.36	0.00e+00	885.00
IUUC-Eeu-034459	Erinaceus europaeus	73.43	2.00e-78	286.00
IUUC-Fca-035447	Felis catus	94.92	0.00e+00	899.00
IUUC-Fal-036605	Ficedula albicollis	87.89	0.00e+00	781.00
IUUC-Fox-037967	Fusarium oxysporum	26.35	1.00e-17	85.50
IUUC-Fso-038110	Fusarium solani	29.33	6.00e-29	122.00
IUUC-Gmo-038785	Gadus morhua	66.67	0.00e+00	673.00
IUUC-Ggr-039760	Gaeumannomyces graminis	29.96	5.00e-26	113.00
IUUC-Gga-040584	Gallus gallus	92.28	0.00e+00	852.00
IUUC-Gac-042469	Gasterosteus aculeatus	64.19	9.00e-168	583.00
IUUC-Gma-044237	Glycine max	37.99	1.00e-26	114.00
IUUC-Ggo-044498	Gorilla gorilla	82.93	0.00e+00	734.00
IUUC-Hsa-046625	Homo sapiens	95.78	0.00e+00	883.00
IUUC-Hvu-047155	Hordeum vulgare	38.20	3.00e-26	113.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	96.14	0.00e+00	872.00
IUUC-Kpa-049160	Komagataella pastoris	29.05	9.00e-25	108.00
IUUC-Lch-050529	Latimeria chalumnae	78.32	0.00e+00	853.00
IUUC-Lpe-051024	Leersia perrieri	32.09	7.00e-29	121.00
IUUC-Loc-052644	Lepisosteus oculatus	70.39	0.00e+00	667.00
IUUC-Lma-053102	Leptosphaeria maculans	31.75	3.00e-27	117.00
IUUC-Laf-054337	Loxodonta africana	94.51	0.00e+00	863.00
IUUC-Mcc-055659	Macaca mulatta	95.60	1.00e-175	609.00
IUUC-Meu-056084	Macropus eugenii	74.66	2.00e-93	336.00
IUUC-Mor-057255	Magnaporthe oryzae	29.24	1.00e-26	115.00
IUUC-Mpo-057454	Magnaporthe poae	29.96	9.00e-28	118.00
IUUC-Mtr-058098	Medicago truncatula	34.55	1.00e-30	127.00
IUUC-Mla-059068	Melampsora laricipopulina	30.14	3.00e-31	129.00
IUUC-Mga-059624	Meleagris gallopavo	78.35	0.00e+00	837.00
IUUC-Mvi-060282	Microbotryum violaceum	48.21	2.00e-20	95.10
IUUC-Mmr-061142	Microcebus murinus	95.59	0.00e+00	889.00
IUUC-Mdo-062289	Monodelphis domestica	92.28	0.00e+00	894.00
IUUC-Mmu-063961	Mus musculus	95.73	0.00e+00	870.00
IUUC-Mac-065188	Musa acuminata	33.07	4.00e-23	102.00
IUUC-Mlu-067431	Myotis lucifugus	91.87	0.00e+00	857.00
IUUC-Nfi-068422	Neosartorya fischeri	30.10	8.00e-30	125.00
IUUC-Ncr-068843	Neurospora crassa	29.89	5.00e-29	122.00
IUUC-Nle-069079	Nomascus leucogenys	95.93	0.00e+00	872.00
IUUC-Opr-070790	Ochotona princeps	95.37	3.00e-57	216.00
IUUC-Ont-071789	Oreochromis niloticus	68.62	1.00e-176	612.00
IUUC-Oan-072946	Ornithorhynchus anatinus	89.45	0.00e+00	817.00
IUUC-Ocu-073816	Oryctolagus cuniculus	97.57	0.00e+00	890.00
IUUC-Oba-075738	Oryza barthii	33.71	9.00e-18	84.70
IUUC-Obr-076355	Oryza brachyantha	38.33	3.00e-27	115.00
IUUC-Ogl-077217	Oryza glaberrima	37.16	2.00e-24	107.00
IUUC-Ogu-078197	Oryza glumaepatula	28.35	1.00e-26	114.00
IUUC-Oin-080047	Oryza indica	33.33	4.00e-26	112.00
IUUC-Olo-080317	Oryza longistaminata	28.35	1.00e-26	113.00
IUUC-Ome-081589	Oryza meridionalis	32.94	6.00e-26	112.00
IUUC-Oni-082700	Oryza nivara	33.71	7.00e-18	85.10
IUUC-Opu-083923	Oryza punctata	34.36	4.00e-21	95.10
IUUC-Oru-084318	Oryza rufipogon	33.71	7.00e-18	85.10
IUUC-Osa-086246	Oryza sativa	38.98	6.00e-06	41.60
IUUC-Ola-086730	Oryzias latipes	56.60	6.00e-149	520.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.08	1.00e-23	103.00
IUUC-Oga-088992	Otolemur garnettii	84.41	0.00e+00	892.00
IUUC-Oar-089789	Ovis aries	96.02	0.00e+00	892.00
IUUC-Ptr-091636	Pan troglodytes	96.14	0.00e+00	873.00
IUUC-Pan-092911	Papio anubis	94.46	0.00e+00	882.00
IUUC-Psi-093194	Pelodiscus sinensis	78.55	0.00e+00	838.00
IUUC-Pma-094212	Petromyzon marinus	49.00	4.00e-114	404.00
IUUC-Pno-094831	Phaeosphaeria nodorum	29.54	3.00e-27	117.00
IUUC-Ppa-095705	Physcomitrella patens	33.33	1.00e-28	121.00
IUUC-Pfo-096694	Poecilia formosa	65.09	9.00e-180	622.00
IUUC-Pab-097706	Pongo abelii	95.97	0.00e+00	879.00
IUUC-Pop-099891	Populus trichocarpa	32.84	3.00e-26	112.00
IUUC-Pca-100879	Procavia capensis	93.93	5.00e-91	327.00
IUUC-Ppe-101334	Prunus persica	31.13	2.00e-26	114.00
IUUC-Pva-103225	Pteropus vampyrus	80.85	0.00e+00	704.00
IUUC-Pgr-103564	Puccinia graminis	30.38	7.00e-31	129.00
IUUC-Ptt-103802	Puccinia triticina	29.41	2.00e-25	110.00
IUUC-Pte-104345	Pyrenophora teres	30.66	2.00e-27	117.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	30.60	2.00e-28	120.00
IUUC-Rno-106101	Rattus norvegicus	94.27	0.00e+00	880.00
IUUC-Sce-106460	Saccharomyces cerevisiae	30.00	9.00e-25	107.00
IUUC-Sha-106919	Sarcophilus harrisii	79.20	0.00e+00	848.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	32.75	8.00e-31	128.00
IUUC-Spo-108087	Schizosaccharomyces pombe	29.96	3.00e-27	116.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	2.00e-07	51.60
IUUC-Smo-109411	Selaginella moellendorffii	36.57	2.00e-28	120.00
IUUC-Sit-110678	Setaria italica	33.33	2.00e-26	113.00
IUUC-Sly-111526	Solanum lycopersicum	36.93	3.00e-25	109.00
IUUC-Stu-112494	Solanum tuberosum	36.36	7.00e-26	111.00
IUUC-Sar-112929	Sorex araneus	96.36	3.00e-161	561.00
IUUC-Sbi-114242	Sorghum bicolor	33.60	9.00e-29	121.00
IUUC-Sre-115224	Sporisorium reilianum	31.79	1.00e-29	125.00
IUUC-Ssc-115239	Sus scrofa	97.56	0.00e+00	891.00
IUUC-Tgu-117499	Taeniopygia guttata	89.23	0.00e+00	818.00
IUUC-Tru-118027	Takifugu rubripes	63.02	2.00e-141	496.00
IUUC-Tsy-119462	Tarsius syrichta	96.44	0.00e+00	856.00
IUUC-Tni-120855	Tetraodon nigroviridis	60.36	3.00e-173	601.00
IUUC-Tca-121213	Theobroma cacao	33.03	3.00e-25	109.00
IUUC-Tre-122186	Trichoderma reesei	29.51	5.00e-28	119.00
IUUC-Tvi-122541	Trichoderma virens	29.59	3.00e-28	120.00
IUUC-Tae-122942	Triticum aestivum	34.51	2.00e-27	116.00
IUUC-Tur-126572	Triticum urartu	39.33	2.00e-26	113.00
IUUC-Tme-127023	Tuber melanosporum	32.93	9.00e-32	132.00
IUUC-Tbe-127453	Tupaia belangeri	97.15	0.00e+00	776.00
IUUC-Ttr-128526	Tursiops truncatus	96.95	0.00e+00	880.00
IUUC-Uma-129660	Ustilago maydis	32.56	6.00e-30	126.00
IUUC-Vda-129737	Verticillium dahliae	28.57	4.00e-24	106.00
IUUC-Vpa-130505	Vicugna pacos	89.90	0.00e+00	707.00
IUUC-Vvi-131088	Vitis vinifera	37.08	5.00e-24	105.00
IUUC-Xtr-132799	Xenopus tropicalis	75.30	0.00e+00	740.00
IUUC-Xma-133345	Xiphophorus maculatus	65.69	3.00e-175	608.00
IUUC-Yli-134416	Yarrowia lipolytica	32.48	5.00e-32	132.00
IUUC-Zma-134750	Zea mays	33.73	4.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence