iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089516

Ensembl Protein ID

ENSOARP00000010430.1

UniProt Accession

W5PJ10; W5PJ10_SHEEP

Genbank Protein ID

ENSOARP00000010430

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01048358

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009726.1	ENSOART00000010585.1	ENSOARP00000010430.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.80e-08	32.9	16	78
E3 activity/RING/RING	4.40e-07	30.5	21	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrl 64
            ee+lC++ ++++rd v+l +G+ + r ++ ++ + +   tcPv++ + ++ dl  n+tl +l
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRGCVTRCWEVQVApTCPVCKDRAAPADLRTNHTLNNL 78
           689******************************9776666********************887 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f++ C+  +w     + + + +CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRGCVtRCW-----EVQVAPTCPVCK 61
           ********99.999***********99999.....789999*****6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGAGAPRPPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRGCVTRCWE VQVAPTCPVC 60
KDRAAPADLR TNHTLNNLAA HKLPHGEAEG ARWTGHRSPR LCRLHRGQFN FFCLDDKELL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGCAG GCGCCCCCCG CCCCCCTGGG CCTTCCCGCT CCTTCAAAGA GGAGCTGCTG 60
TGCGCCGTCT GCTATGACCC CTTCCGCGAT GCCGTGACTC TGCGCTGCGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	90.47	0.00e+00	924.00
IUUC-Apl-003958	Anas platyrhynchos	52.39	8.00e-128	450.00
IUUC-Aca-005199	Anolis carolinensis	45.87	7.00e-121	427.00
IUUC-Ame-011964	Astyanax mexicanus	35.62	1.00e-70	260.00
IUUC-Bta-013359	Bos taurus	97.30	0.00e+00	970.00
IUUC-Cja-018900	Callithrix jacchus	74.65	0.00e+00	750.00
IUUC-Cfa-020685	Canis familiaris	90.08	0.00e+00	920.00
IUUC-Cpo-022253	Cavia porcellus	78.35	0.00e+00	766.00
IUUC-Csa-023777	Chlorocebus sabaeus	88.45	0.00e+00	898.00
IUUC-Dre-028296	Danio rerio	32.02	7.00e-69	254.00
IUUC-Dno-029065	Dasypus novemcinctus	84.95	0.00e+00	856.00
IUUC-Dor-030248	Dipodomys ordii	59.70	4.00e-93	333.00
IUUC-Ete-033183	Echinops telfairi	74.49	0.00e+00	717.00
IUUC-Eca-033263	Equus caballus	88.77	0.00e+00	816.00
IUUC-Eeu-034699	Erinaceus europaeus	81.59	1.00e-115	409.00
IUUC-Fca-036366	Felis catus	88.64	0.00e+00	906.00
IUUC-Fal-037257	Ficedula albicollis	54.36	1.00e-150	526.00
IUUC-Gmo-038512	Gadus morhua	35.15	2.00e-69	256.00
IUUC-Gga-041125	Gallus gallus	53.49	3.00e-104	371.00
IUUC-Gac-042136	Gasterosteus aculeatus	35.37	9.00e-68	250.00
IUUC-Ggo-045233	Gorilla gorilla	88.25	7.00e-168	582.00
IUUC-Hsa-046042	Homo sapiens	88.45	0.00e+00	899.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	86.49	0.00e+00	870.00
IUUC-Loc-051729	Lepisosteus oculatus	35.12	6.00e-79	288.00
IUUC-Laf-054322	Loxodonta africana	88.31	0.00e+00	891.00
IUUC-Mcc-055555	Macaca mulatta	86.35	0.00e+00	879.00
IUUC-Meu-055900	Macropus eugenii	76.52	0.00e+00	761.00
IUUC-Mga-059380	Meleagris gallopavo	55.17	2.00e-100	358.00
IUUC-Mmr-061296	Microcebus murinus	86.39	0.00e+00	867.00
IUUC-Mdo-062811	Monodelphis domestica	76.15	0.00e+00	763.00
IUUC-Mmu-063718	Mus musculus	76.59	0.00e+00	775.00
IUUC-Mpu-066219	Mustela putorius furo	91.06	0.00e+00	909.00
IUUC-Mlu-067033	Myotis lucifugus	83.95	0.00e+00	861.00
IUUC-Nle-069806	Nomascus leucogenys	88.33	0.00e+00	838.00
IUUC-Opr-070248	Ochotona princeps	76.73	0.00e+00	745.00
IUUC-Ont-072083	Oreochromis niloticus	31.44	3.00e-67	249.00
IUUC-Oan-073364	Ornithorhynchus anatinus	67.74	1.00e-97	349.00
IUUC-Ocu-074572	Oryctolagus cuniculus	87.42	0.00e+00	905.00
IUUC-Ola-086686	Oryzias latipes	32.07	8.00e-59	221.00
IUUC-Oga-088378	Otolemur garnettii	84.77	0.00e+00	847.00
IUUC-Ptr-091313	Pan troglodytes	88.45	0.00e+00	899.00
IUUC-Pan-092877	Papio anubis	88.66	0.00e+00	899.00
IUUC-Psi-093928	Pelodiscus sinensis	57.59	1.00e-157	549.00
IUUC-Pfo-096690	Poecilia formosa	34.87	4.00e-69	255.00
IUUC-Pab-098624	Pongo abelii	88.04	0.00e+00	890.00
IUUC-Pca-100469	Procavia capensis	80.62	0.00e+00	815.00
IUUC-Pva-103227	Pteropus vampyrus	90.41	0.00e+00	915.00
IUUC-Rno-105778	Rattus norvegicus	76.39	0.00e+00	775.00
IUUC-Sha-107392	Sarcophilus harrisii	67.07	0.00e+00	650.00
IUUC-Sar-113297	Sorex araneus	69.23	8.00e-50	190.00
IUUC-Ssc-115739	Sus scrofa	91.06	0.00e+00	912.00
IUUC-Tru-117718	Takifugu rubripes	30.83	2.00e-60	226.00
IUUC-Tbe-127926	Tupaia belangeri	73.08	0.00e+00	697.00
IUUC-Ttr-129293	Tursiops truncatus	91.68	0.00e+00	934.00
IUUC-Vpa-130379	Vicugna pacos	91.61	6.00e-162	562.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence