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Tag Content
UUCD2 ID IUUC-Cja-019619
UUCD1 version UUC-CaJ-01111
Ensembl Protein ID ENSCJAP00000051800.1
UniProt Accession F6TR57; F6TR57_CALJA
Genbank Protein ID ENSCJAP00000004969
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ACFV01061277
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000002734.2 ENSCJAT00000063539.1 ENSCJAP00000051800.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.40e-97 327.1 273 677
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.........kkkeklneenp...................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+          ++e      +                                      
   Q: 273  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnqwlavTTSE------Ktrsykhppvtdtvvyqmdecqekdagfvrsrhsslssg 355
           7******************************8887666652222......133444577899999999999999999999999999999 PP
   S: 43   ...................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkekn 112
                              +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el     
   Q: 356  lsggaskgrkmeliqprepTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHEL----- 439
           999998888888888877777777************************************************************..... PP
   S: 113  kpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcLesf 194
               e+++++  +l   +++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ +++ +        ++++L++f
   Q: 440  ----ETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKdtasqpcLVTEMLAKF 524
           ....7889999999999************************************************877776667777777********* PP
   S: 195  tkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekq 272
           t++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++++ k+
   Q: 525  TETEALEGKI-YVCDQCNSKRRrfsskpvvlteAQKQLMICHLPQVLRLHLKRFRWSGR-SNREKIGVHVVFEEILNMEPYCCRETLKS 611
           *******965.*******999999999999999***********************998.7778********************99888 PP
   S: 273  ke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
            +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 612  LRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSMCTMDEVCK---AQAYILFYTQ 677
           76779***************************9999********************...********98 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MLTMDTCKHV GQLQLAQDHS ILDPQKWHCM DCNTTESIWA CLSCSHVACG RYIEEHALKH 60
FQESSHPVAL EVNEMYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY HCTTHSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-019619|DUB,USP|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTCAGGAAAG CAGTTTCCAG GAGCTGAGAG TTTAAGCCAG ACCTGAAAGA GGTTGATTTG 60
TAATGATTTT CAGGAGGCCA CTGGAGGCAG CGGCCAGGGT TTCCACTTAG GAGATCAACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-019619|DUB,USP|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cjc:100410482
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 91.16 0.00e+00 1310.00
IUUC-Apl-003673 Anas platyrhynchos 74.51 0.00e+00 1039.00
IUUC-Aca-004434 Anolis carolinensis 71.55 0.00e+00 1012.00
IUUC-Ame-010986 Astyanax mexicanus 64.57 0.00e+00 869.00
IUUC-Bta-012774 Bos taurus 89.06 0.00e+00 1273.00
IUUC-Cfa-020957 Canis familiaris 90.46 0.00e+00 1317.00
IUUC-Csa-023177 Chlorocebus sabaeus 92.99 0.00e+00 1317.00
IUUC-Cho-024877 Choloepus hoffmanni 87.18 0.00e+00 840.00
IUUC-Csv-025814 Ciona savignyi 44.06 8.00e-150 524.00
IUUC-Dre-027878 Danio rerio 63.81 0.00e+00 842.00
IUUC-Dno-029832 Dasypus novemcinctus 90.31 0.00e+00 1314.00
IUUC-Ete-032627 Echinops telfairi 85.41 0.00e+00 1239.00
IUUC-Eca-033863 Equus caballus 86.76 0.00e+00 1211.00
IUUC-Eeu-035225 Erinaceus europaeus 85.55 0.00e+00 1195.00
IUUC-Fca-036288 Felis catus 90.74 0.00e+00 1309.00
IUUC-Fal-037207 Ficedula albicollis 75.14 0.00e+00 1008.00
IUUC-Gga-040457 Gallus gallus 73.66 0.00e+00 1011.00
IUUC-Ggo-044926 Gorilla gorilla 93.40 0.00e+00 1318.00
IUUC-Hsa-046079 Homo sapiens 93.68 0.00e+00 1323.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 90.45 0.00e+00 1290.00
IUUC-Lch-050260 Latimeria chalumnae 66.29 0.00e+00 916.00
IUUC-Laf-054491 Loxodonta africana 87.54 0.00e+00 1208.00
IUUC-Mcc-055694 Macaca mulatta 92.99 0.00e+00 1314.00
IUUC-Mga-059523 Meleagris gallopavo 73.63 0.00e+00 1028.00
IUUC-Mmr-060885 Microcebus murinus 93.13 0.00e+00 1331.00
IUUC-Mdo-063018 Monodelphis domestica 79.07 0.00e+00 1108.00
IUUC-Mmu-064012 Mus musculus 80.62 0.00e+00 1107.00
IUUC-Mpu-066207 Mustela putorius furo 89.34 0.00e+00 1313.00
IUUC-Mlu-066929 Myotis lucifugus 86.79 0.00e+00 1182.00
IUUC-Nle-069313 Nomascus leucogenys 82.80 0.00e+00 1130.00
IUUC-Opr-070375 Ochotona princeps 82.05 0.00e+00 1129.00
IUUC-Ont-071637 Oreochromis niloticus 63.04 0.00e+00 855.00
IUUC-Oan-073030 Ornithorhynchus anatinus 77.49 0.00e+00 839.00
IUUC-Ocu-074836 Oryctolagus cuniculus 87.31 0.00e+00 1256.00
IUUC-Oga-088367 Otolemur garnettii 92.57 0.00e+00 1305.00
IUUC-Oar-089953 Ovis aries 90.20 0.00e+00 1308.00
IUUC-Ptr-090980 Pan troglodytes 93.54 0.00e+00 1322.00
IUUC-Pan-092748 Papio anubis 93.41 0.00e+00 1318.00
IUUC-Pab-098514 Pongo abelii 92.85 0.00e+00 1311.00
IUUC-Pva-102984 Pteropus vampyrus 88.50 0.00e+00 1238.00
IUUC-Rno-106019 Rattus norvegicus 80.56 0.00e+00 1141.00
IUUC-Sha-106965 Sarcophilus harrisii 78.12 0.00e+00 1102.00
IUUC-Ssc-115299 Sus scrofa 90.74 0.00e+00 1320.00
IUUC-Tgu-117160 Taeniopygia guttata 73.58 0.00e+00 1003.00
IUUC-Tru-118156 Takifugu rubripes 60.68 0.00e+00 827.00
IUUC-Tni-119733 Tetraodon nigroviridis 61.35 0.00e+00 843.00
IUUC-Tbe-128084 Tupaia belangeri 85.11 0.00e+00 1211.00
IUUC-Ttr-128928 Tursiops truncatus 91.58 0.00e+00 1323.00
IUUC-Vpa-130706 Vicugna pacos 91.44 0.00e+00 1313.00
IUUC-Xtr-132061 Xenopus tropicalis 70.62 0.00e+00 910.00
Created Date 25-Jun-2017

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