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Tag Content
UUCD2 ID IUUC-Oga-088367
UUCD1 version UUC-OtG-00775
Ensembl Protein ID ENSOGAP00000007590.2
UniProt Accession H0WYJ8; H0WYJ8_OTOGA
Genbank Protein ID ENSOGAP00000007590
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAQR03016783
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000008473.2 ENSOGAT00000008476.2 ENSOGAP00000007590.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.90e-97 324.6 273 678
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenp.................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+           ++        +                                    
   Q: 273  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnqwlavtaSD--------Ktrssykhppvtdtlvcqmnecqekdtsfvrsrhysl 353
           7******************************8777666654422........1334444568889999999999988899999999999 PP
   S: 43   ......................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk 109
                                 +++  +l+++l++lf+ +w++++  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el  
   Q: 354  ssglsggasksrkmeliqprepSSQYISLCHELHTLFQVMWSGRWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHEL-- 440
           999999998888888888877777777************************************************************.. PP
   S: 110  eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcL 191
                  e+++++  +l   +++k  k+  ++++++F+gql sq++cl+cdn+s++ epf+dlsl++p++ +++ +        ++++L
   Q: 441  -------ETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKdaasqpcLVTEML 522
           .......7889999999999************************************************888877668888888****** PP
   S: 192  esftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspe 269
           ++ft++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++++
   Q: 523  AKFTETEALEGKI-YVCDQCNSKRRrfssksvvlteAQKQLMICHLPQVLRLHLKRFRWSGR-NNREKIGVHVGFEEILNMEPYCCRET 609
           **********965.*******999999999999999***********************998.7778********************99 PP
   S: 270  ekqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
            k+ +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 610  LKSLRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSLCTMDEVCK---AQAYILFYTQ 678
           88876779***************************9999********************...********98 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
MLTMDKCKHV GQLRLAQDHS ILNPQKWHCV DCNTTESIWA CLSCSHVACG RYIEEHALKH 60
FQESSHPVAL EVNEMYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY YCTTRSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088367|DUB,USP|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGTTTTCAG ATACTTCAAG TATTGTGAAC AGAGACTGAT TTGGATTATG TGTTTCTCAG 60
CTAGACTAAA TAAATGTTAA CAATGGATAA ATGCAAACAC GTTGGGCAGT TGCGACTTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088367|DUB,USP|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 93.13 0.00e+00 1323.00
IUUC-Apl-003673 Anas platyrhynchos 76.16 0.00e+00 1066.00
IUUC-Aca-004434 Anolis carolinensis 73.26 0.00e+00 1045.00
IUUC-Ame-010986 Astyanax mexicanus 64.91 0.00e+00 885.00
IUUC-Bta-012774 Bos taurus 90.88 0.00e+00 1284.00
IUUC-Cja-019619 Callithrix jacchus 92.57 0.00e+00 1294.00
IUUC-Cfa-020957 Canis familiaris 92.29 0.00e+00 1335.00
IUUC-Csa-023177 Chlorocebus sabaeus 92.43 0.00e+00 1293.00
IUUC-Cho-024877 Choloepus hoffmanni 90.36 0.00e+00 845.00
IUUC-Cin-025587 Ciona intestinalis 48.97 4.00e-109 389.00
IUUC-Csv-025814 Ciona savignyi 44.89 9.00e-153 533.00
IUUC-Dre-027878 Danio rerio 73.13 0.00e+00 627.00
IUUC-Dno-029832 Dasypus novemcinctus 91.58 0.00e+00 1308.00
IUUC-Ete-032627 Echinops telfairi 87.54 0.00e+00 1239.00
IUUC-Eca-033863 Equus caballus 88.03 0.00e+00 1229.00
IUUC-Eeu-035225 Erinaceus europaeus 86.26 0.00e+00 1191.00
IUUC-Fca-036288 Felis catus 92.57 0.00e+00 1322.00
IUUC-Fal-037207 Ficedula albicollis 74.23 0.00e+00 1014.00
IUUC-Gga-040457 Gallus gallus 74.47 0.00e+00 1030.00
IUUC-Ggo-044926 Gorilla gorilla 92.71 0.00e+00 1291.00
IUUC-Hsa-046079 Homo sapiens 92.15 0.00e+00 1289.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 91.44 0.00e+00 1281.00
IUUC-Lch-050260 Latimeria chalumnae 67.79 0.00e+00 931.00
IUUC-Laf-054491 Loxodonta africana 89.57 0.00e+00 1221.00
IUUC-Mcc-055694 Macaca mulatta 92.85 0.00e+00 1295.00
IUUC-Mga-059523 Meleagris gallopavo 74.44 0.00e+00 1046.00
IUUC-Mmr-060885 Microcebus murinus 94.81 0.00e+00 1345.00
IUUC-Mdo-063018 Monodelphis domestica 80.06 0.00e+00 1124.00
IUUC-Mmu-064012 Mus musculus 81.07 0.00e+00 1101.00
IUUC-Mpu-066207 Mustela putorius furo 91.30 0.00e+00 1330.00
IUUC-Mlu-066929 Myotis lucifugus 88.14 0.00e+00 1191.00
IUUC-Nle-069313 Nomascus leucogenys 82.66 0.00e+00 1113.00
IUUC-Opr-070375 Ochotona princeps 82.91 0.00e+00 1129.00
IUUC-Ont-071637 Oreochromis niloticus 63.57 0.00e+00 867.00
IUUC-Oan-073030 Ornithorhynchus anatinus 79.04 0.00e+00 859.00
IUUC-Ocu-074836 Oryctolagus cuniculus 88.31 0.00e+00 1243.00
IUUC-Oar-089953 Ovis aries 91.88 0.00e+00 1320.00
IUUC-Ptr-090980 Pan troglodytes 92.29 0.00e+00 1291.00
IUUC-Pan-092748 Papio anubis 93.13 0.00e+00 1296.00
IUUC-Pab-098514 Pongo abelii 92.57 0.00e+00 1294.00
IUUC-Pva-102984 Pteropus vampyrus 91.97 0.00e+00 1274.00
IUUC-Rno-106019 Rattus norvegicus 80.17 0.00e+00 1129.00
IUUC-Sha-106965 Sarcophilus harrisii 79.15 0.00e+00 1118.00
IUUC-Ssc-115299 Sus scrofa 91.87 0.00e+00 1324.00
IUUC-Tgu-117160 Taeniopygia guttata 74.74 0.00e+00 1019.00
IUUC-Tru-118156 Takifugu rubripes 61.21 0.00e+00 841.00
IUUC-Tni-119733 Tetraodon nigroviridis 62.21 0.00e+00 857.00
IUUC-Tbe-128084 Tupaia belangeri 85.39 0.00e+00 1233.00
IUUC-Ttr-128928 Tursiops truncatus 93.41 0.00e+00 1330.00
IUUC-Vpa-130706 Vicugna pacos 92.57 0.00e+00 1318.00
IUUC-Xtr-132061 Xenopus tropicalis 72.15 0.00e+00 957.00
Created Date 25-Jun-2017

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