iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044969

Ensembl Protein ID

ENSGGOP00000015859.2

UniProt Accession

G3RJG8; G3RJG8_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016254.2	ENSGGOT00000016311.2	ENSGGOP00000015859.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.90e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	6.00e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAESGESGGP PGSQDSAAGA EGAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATTTCGCTA ACCGTGACGT CATCTCGGTG CGCCGTTACA GCGCTTAACT GGAAACTGCG 60
ATTTAGTTTT TGGTGAAAGG AGTGGAAAAA AACCCATGAA CTGACCTACC CCGCCCCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ggo:101131379

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	8.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	95.88	0.00e+00	809.00
IUUC-Atr-002470	Amborella trichopoda	39.78	4.00e-44	172.00
IUUC-Apl-003241	Anas platyrhynchos	83.40	0.00e+00	717.00
IUUC-Aca-004511	Anolis carolinensis	80.11	0.00e+00	724.00
IUUC-Aly-005419	Arabidopsis lyrata	34.28	1.00e-51	197.00
IUUC-Ath-007350	Arabidopsis thaliana	34.46	9.00e-52	197.00
IUUC-Ago-007963	Ashbya gossypii	37.68	1.00e-08	53.90
IUUC-Bta-013048	Bos taurus	94.55	0.00e+00	827.00
IUUC-Bdi-014506	Brachypodium distachyon	35.45	9.00e-52	197.00
IUUC-Bol-015326	Brassica oleracea	33.22	5.00e-53	201.00
IUUC-Bra-018014	Brassica rapa	37.37	1.00e-41	163.00
IUUC-Cel-018631	Caenorhabditis elegans	38.48	2.00e-67	249.00
IUUC-Cja-019976	Callithrix jacchus	98.02	0.00e+00	843.00
IUUC-Cfa-020092	Canis familiaris	96.04	0.00e+00	834.00
IUUC-Cpo-022388	Cavia porcellus	96.04	0.00e+00	830.00
IUUC-Csa-024087	Chlorocebus sabaeus	99.27	0.00e+00	844.00
IUUC-Cho-024834	Choloepus hoffmanni	96.53	0.00e+00	844.00
IUUC-Cin-025136	Ciona intestinalis	51.10	1.00e-113	403.00
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dor-030519	Dipodomys ordii	92.81	0.00e+00	805.00
IUUC-Dme-032013	Drosophila melanogaster	46.75	2.00e-115	409.00
IUUC-Ete-032273	Echinops telfairi	94.90	0.00e+00	808.00
IUUC-Eca-033667	Equus caballus	95.08	0.00e+00	834.00
IUUC-Fca-036179	Felis catus	92.81	0.00e+00	789.00
IUUC-Fal-037642	Ficedula albicollis	82.47	0.00e+00	771.00
IUUC-Gga-041264	Gallus gallus	83.33	0.00e+00	804.00
IUUC-Gma-043430	Glycine max	35.27	2.00e-44	173.00
IUUC-Hsa-046669	Homo sapiens	99.82	0.00e+00	857.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	96.71	0.00e+00	687.00
IUUC-Lch-050192	Latimeria chalumnae	77.26	0.00e+00	674.00
IUUC-Lpe-051401	Leersia perrieri	37.38	4.00e-36	145.00
IUUC-Loc-052846	Lepisosteus oculatus	77.61	0.00e+00	670.00
IUUC-Lma-053152	Leptosphaeria maculans	30.29	2.00e-11	64.30
IUUC-Laf-054278	Loxodonta africana	94.91	0.00e+00	797.00
IUUC-Mcc-055680	Macaca mulatta	99.28	0.00e+00	857.00
IUUC-Meu-056414	Macropus eugenii	79.39	6.00e-156	543.00
IUUC-Mtr-058674	Medicago truncatula	34.88	2.00e-47	183.00
IUUC-Mga-059894	Meleagris gallopavo	82.44	0.00e+00	647.00
IUUC-Mmr-061094	Microcebus murinus	97.12	0.00e+00	830.00
IUUC-Mdo-062728	Monodelphis domestica	86.03	0.00e+00	772.00
IUUC-Mmu-064088	Mus musculus	86.15	0.00e+00	835.00
IUUC-Mac-065458	Musa acuminata	36.02	3.00e-44	172.00
IUUC-Mpu-066282	Mustela putorius furo	92.27	0.00e+00	803.00
IUUC-Mlu-068158	Myotis lucifugus	94.23	0.00e+00	793.00
IUUC-Nle-069321	Nomascus leucogenys	99.64	0.00e+00	857.00
IUUC-Opr-071098	Ochotona princeps	89.50	0.00e+00	626.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.64	0.00e+00	737.00
IUUC-Ocu-074301	Oryctolagus cuniculus	87.96	0.00e+00	786.00
IUUC-Oba-074973	Oryza barthii	38.69	4.00e-43	169.00
IUUC-Obr-076444	Oryza brachyantha	49.66	5.00e-32	132.00
IUUC-Ogl-077319	Oryza glaberrima	38.69	1.00e-43	171.00
IUUC-Ogu-078074	Oryza glumaepatula	35.07	1.00e-50	194.00
IUUC-Oin-079142	Oryza indica	38.36	1.00e-43	171.00
IUUC-Olo-080565	Oryza longistaminata	34.84	7.00e-49	188.00
IUUC-Ome-081155	Oryza meridionalis	45.67	4.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	38.36	1.00e-43	171.00
IUUC-Opu-083241	Oryza punctata	36.75	4.00e-52	199.00
IUUC-Oru-085257	Oryza rufipogon	38.36	1.00e-43	171.00
IUUC-Osa-086257	Oryza sativa	38.69	1.00e-43	171.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.12	9.00e-26	111.00
IUUC-Oga-088495	Otolemur garnettii	96.58	0.00e+00	806.00
IUUC-Oar-089711	Ovis aries	94.06	0.00e+00	803.00
IUUC-Ptr-091439	Pan troglodytes	99.46	0.00e+00	850.00
IUUC-Pan-092641	Papio anubis	99.28	0.00e+00	857.00
IUUC-Psi-093518	Pelodiscus sinensis	83.33	0.00e+00	719.00
IUUC-Pma-094727	Petromyzon marinus	43.58	2.00e-52	200.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	1.00e-35	144.00
IUUC-Pfo-096638	Poecilia formosa	67.68	1.00e-173	602.00
IUUC-Pab-098699	Pongo abelii	97.30	0.00e+00	848.00
IUUC-Pop-099549	Populus trichocarpa	36.87	7.00e-55	208.00
IUUC-Pca-100497	Procavia capensis	83.81	9.00e-135	473.00
IUUC-Ppe-101901	Prunus persica	35.00	4.00e-57	215.00
IUUC-Pva-102513	Pteropus vampyrus	83.48	6.00e-147	514.00
IUUC-Rno-104908	Rattus norvegicus	86.66	0.00e+00	872.00
IUUC-Sha-106881	Sarcophilus harrisii	84.14	0.00e+00	698.00
IUUC-Smo-108910	Selaginella moellendorffii	35.47	6.00e-38	151.00
IUUC-Sit-110766	Setaria italica	39.34	2.00e-36	146.00
IUUC-Sar-113648	Sorex araneus	87.47	0.00e+00	632.00
IUUC-Sbi-114307	Sorghum bicolor	37.46	7.00e-45	174.00
IUUC-Ssc-115820	Sus scrofa	96.58	0.00e+00	837.00
IUUC-Tgu-116845	Taeniopygia guttata	78.20	0.00e+00	685.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.78	2.00e-171	595.00
IUUC-Tca-121558	Theobroma cacao	35.31	1.00e-54	207.00
IUUC-Tae-125419	Triticum aestivum	49.65	8.00e-38	151.00
IUUC-Tur-126783	Triticum urartu	54.48	3.00e-38	152.00
IUUC-Tbe-127379	Tupaia belangeri	83.21	0.00e+00	674.00
IUUC-Ttr-128630	Tursiops truncatus	93.58	0.00e+00	837.00
IUUC-Vpa-130413	Vicugna pacos	70.73	3.00e-159	554.00
IUUC-Vvi-131599	Vitis vinifera	39.67	9.00e-43	168.00
IUUC-Xtr-132595	Xenopus tropicalis	79.15	0.00e+00	707.00
IUUC-Xma-134155	Xiphophorus maculatus	64.66	2.00e-168	585.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence