iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041105

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000707

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000013348.5	ENSGALT00000021781.5	ENSGALP00000021745.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	2.20e-37	128.9	170	351

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++ l++ + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 170  LPLATTGDGNCLLHAASLGMWGFHDRDLvLRKSLYTLMDKGVEREALKRRWRWQQTQQNKesglvyteeewQKEWNELIKLASSEprvh 258
           6899*********************************************************************************8877 PP
   S: 75   ..akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYda 134
             + g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p++k +++p+vL+Y+++H++a
   Q: 259  ygTNGggcggvesseepvyeslEEFHVFVLAHVLKRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPANKcHRSPLVLAYDQAHFSA 347
           7522367788******************************************************************************* PP
   S: 135  Lval 138
           Lv++
   Q: 348  LVSM 351
           *986 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MDIVLSDFVR STGAEPGLAR DLLEGKNWDV SAALSDFEQL RQVHAGNLPH SFNEGRSYKP 60
PEKEAARPGR PPLQRQDDIV QEKRLSRGIS HASSTIVSLA RSHVSSNGSS EHLLEMPIST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTTTCTT CTGCCTTCCA AAAGGCCTCT TGCTTTTAAG TGCTGAACCC ACCAGAAGGA 60
AGTTACCTTT TGCTCCGGCG ATGCTGAGTT TTCACTGAGA AACCCCACTC GCTGCTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR002653--Znf_A20

PROSITE

PS50802--OTU
PS51036--ZF_A20

Pfam

PF02338--OTU
PF01754--zf-A20

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

KEGG

gga:426041

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	68.34	0.00e+00	1004.00
IUUC-Apl-003567	Anas platyrhynchos	86.89	0.00e+00	1276.00
IUUC-Bta-013398	Bos taurus	68.48	0.00e+00	982.00
IUUC-Cel-018468	Caenorhabditis elegans	49.16	5.00e-84	305.00
IUUC-Cja-019965	Callithrix jacchus	67.05	0.00e+00	1000.00
IUUC-Cfa-020191	Canis familiaris	68.78	0.00e+00	999.00
IUUC-Cpo-022232	Cavia porcellus	67.90	0.00e+00	970.00
IUUC-Csa-023593	Chlorocebus sabaeus	68.63	0.00e+00	1049.00
IUUC-Csv-026177	Ciona savignyi	33.90	2.00e-03	35.00
IUUC-Dno-029900	Dasypus novemcinctus	67.66	0.00e+00	970.00
IUUC-Dor-031121	Dipodomys ordii	75.88	5.00e-174	603.00
IUUC-Ete-032473	Echinops telfairi	71.10	0.00e+00	824.00
IUUC-Eca-033946	Equus caballus	75.84	0.00e+00	851.00
IUUC-Eeu-034670	Erinaceus europaeus	67.24	0.00e+00	960.00
IUUC-Fca-035871	Felis catus	66.86	0.00e+00	960.00
IUUC-Gmo-039373	Gadus morhua	82.71	0.00e+00	712.00
IUUC-Gac-041806	Gasterosteus aculeatus	82.74	0.00e+00	766.00
IUUC-Ggo-045472	Gorilla gorilla	67.46	0.00e+00	1013.00
IUUC-Hsa-046473	Homo sapiens	67.46	0.00e+00	1021.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	68.93	0.00e+00	1002.00
IUUC-Lch-050432	Latimeria chalumnae	71.61	0.00e+00	1102.00
IUUC-Mcc-055261	Macaca mulatta	68.52	0.00e+00	1050.00
IUUC-Meu-056477	Macropus eugenii	66.45	0.00e+00	792.00
IUUC-Mga-059533	Meleagris gallopavo	93.71	0.00e+00	1445.00
IUUC-Mdo-062847	Monodelphis domestica	66.04	0.00e+00	971.00
IUUC-Mmu-064260	Mus musculus	67.20	0.00e+00	939.00
IUUC-Mpu-066876	Mustela putorius furo	64.89	0.00e+00	928.00
IUUC-Mlu-068039	Myotis lucifugus	67.23	0.00e+00	1007.00
IUUC-Nle-069260	Nomascus leucogenys	67.87	0.00e+00	1019.00
IUUC-Ola-086490	Oryzias latipes	57.54	0.00e+00	847.00
IUUC-Oga-088124	Otolemur garnettii	67.51	0.00e+00	980.00
IUUC-Oar-090086	Ovis aries	68.47	0.00e+00	978.00
IUUC-Ptr-091622	Pan troglodytes	76.55	0.00e+00	897.00
IUUC-Pan-092724	Papio anubis	68.52	0.00e+00	1043.00
IUUC-Psi-093333	Pelodiscus sinensis	81.14	0.00e+00	1265.00
IUUC-Pab-098667	Pongo abelii	67.98	0.00e+00	1011.00
IUUC-Pva-102136	Pteropus vampyrus	67.67	0.00e+00	978.00
IUUC-Rno-105546	Rattus norvegicus	68.22	0.00e+00	957.00
IUUC-Sha-106732	Sarcophilus harrisii	66.78	0.00e+00	891.00
IUUC-Sar-113562	Sorex araneus	62.39	0.00e+00	799.00
IUUC-Ssc-116191	Sus scrofa	68.60	0.00e+00	994.00
IUUC-Tgu-116942	Taeniopygia guttata	91.40	0.00e+00	963.00
IUUC-Tru-117911	Takifugu rubripes	80.53	0.00e+00	748.00
IUUC-Tsy-119343	Tarsius syrichta	69.37	0.00e+00	885.00
IUUC-Tbe-127283	Tupaia belangeri	81.03	0.00e+00	668.00
IUUC-Ttr-128692	Tursiops truncatus	63.99	0.00e+00	900.00
IUUC-Xtr-132888	Xenopus tropicalis	70.59	0.00e+00	1072.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence