iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059214

UUCD1 version

UUC-MeG-00481

Ensembl Protein ID

ENSMGAP00000010749.2

UniProt Accession

G1ND55; G1ND55_MELGA

Protein Name

Uncharacterized protein

Gene Name

SOCS5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010361.2	ENSMGAT00000011612.2	ENSMGAP00000010749.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	7.70e-16	57.5	475	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            l r+ p+SLq++CR +I+rc++++++   d LPLP++L+d+L++++y+
   Q: 475  SLNRTFPFSLQYICRAVICRCTTYDGI---DDLPLPSMLQDFLKEYHYK 520
           577899*********************...****************985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDKVGKMWNN FKYRCQNLFS HEGGSQNENV VINSSSCSSA KDRTVQITGL TQQRPSSPLR 60
ENIALQLGLS PSKNSVRRNQ NCVTEIPQIV EISIEKENDS CVTTGARLAR RDSYSRHAPW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGATAACAT AATCCATGGA TAAAGTGGGA AAGATGTGGA ACAATTTCAA ATACAGGTGC 60
CAGAATCTCT TCAGTCATGA AGGCGGAAGC CAAAATGAAA ATGTAGTCAT TAACTCCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0071404--P:cellular response to low-density lipoprotein particle stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0050728--P:negative regulation of inflammatory response
GO:0032715--P:negative regulation of interleukin-6 production
GO:0071638--P:negative regulation of monocyte chemotactic protein-1 production
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045627--P:positive regulation of T-helper 1 cell differentiation
GO:0016567--P:protein ubiquitination
GO:0097699--P:vascular endothelial cell response to fluid shear stress

KEGG

mgp:100546544

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	32.65	1.00e-01	29.30
IUUC-Aml-001789	Ailuropoda melanoleuca	54.45	4.00e-113	401.00
IUUC-Apl-003815	Anas platyrhynchos	97.01	0.00e+00	1070.00
IUUC-Aca-004504	Anolis carolinensis	86.01	0.00e+00	878.00
IUUC-Ame-010677	Astyanax mexicanus	63.07	0.00e+00	634.00
IUUC-Bta-012338	Bos taurus	90.30	0.00e+00	977.00
IUUC-Bol-016597	Brassica oleracea	41.03	3.30e-01	29.60
IUUC-Cja-019828	Callithrix jacchus	90.67	0.00e+00	961.00
IUUC-Cfa-020369	Canis familiaris	90.67	0.00e+00	981.00
IUUC-Cpo-021397	Cavia porcellus	88.62	0.00e+00	984.00
IUUC-Csa-023856	Chlorocebus sabaeus	90.49	0.00e+00	978.00
IUUC-Cho-024700	Choloepus hoffmanni	54.91	1.00e-118	419.00
IUUC-Dre-028262	Danio rerio	63.23	3.00e-170	590.00
IUUC-Dno-029019	Dasypus novemcinctus	90.67	0.00e+00	1001.00
IUUC-Dor-030273	Dipodomys ordii	54.83	2.00e-113	402.00
IUUC-Dme-031965	Drosophila melanogaster	67.44	8.00e-70	258.00
IUUC-Ete-032972	Echinops telfairi	58.20	1.00e-99	355.00
IUUC-Eca-033867	Equus caballus	89.93	0.00e+00	992.00
IUUC-Eeu-035208	Erinaceus europaeus	54.99	3.00e-112	397.00
IUUC-Fca-035806	Felis catus	90.49	0.00e+00	972.00
IUUC-Fal-037117	Ficedula albicollis	95.90	0.00e+00	1043.00
IUUC-Gmo-039066	Gadus morhua	83.89	3.00e-107	382.00
IUUC-Gga-040876	Gallus gallus	98.69	0.00e+00	1050.00
IUUC-Gac-042149	Gasterosteus aculeatus	65.93	0.00e+00	636.00
IUUC-Ggo-045169	Gorilla gorilla	89.74	0.00e+00	973.00
IUUC-Hsa-045805	Homo sapiens	90.86	0.00e+00	980.00
IUUC-Hvu-047122	Hordeum vulgare	39.02	8.00e-03	33.50
IUUC-Itr-049048	Ictidomys tridecemlineatus	89.93	0.00e+00	994.00
IUUC-Lch-049686	Latimeria chalumnae	80.52	0.00e+00	856.00
IUUC-Lpe-051639	Leersia perrieri	29.23	2.00e-01	30.40
IUUC-Loc-051745	Lepisosteus oculatus	72.79	0.00e+00	721.00
IUUC-Lma-053042	Leptosphaeria maculans	25.00	1.00e+00	30.80
IUUC-Laf-054124	Loxodonta africana	88.45	0.00e+00	975.00
IUUC-Mcc-055175	Macaca mulatta	90.49	0.00e+00	978.00
IUUC-Meu-056557	Macropus eugenii	89.98	0.00e+00	990.00
IUUC-Mvi-060418	Microbotryum violaceum	29.63	5.50e-01	27.30
IUUC-Mmr-060613	Microcebus murinus	76.12	0.00e+00	763.00
IUUC-Mdo-062788	Monodelphis domestica	89.98	0.00e+00	954.00
IUUC-Mmu-064333	Mus musculus	88.62	0.00e+00	963.00
IUUC-Mpu-066048	Mustela putorius furo	90.86	0.00e+00	981.00
IUUC-Mlu-067430	Myotis lucifugus	90.11	0.00e+00	956.00
IUUC-Nle-069086	Nomascus leucogenys	90.49	0.00e+00	1000.00
IUUC-Opr-070312	Ochotona princeps	86.57	0.00e+00	931.00
IUUC-Ont-072299	Oreochromis niloticus	63.96	0.00e+00	635.00
IUUC-Ocu-074123	Oryctolagus cuniculus	85.82	0.00e+00	919.00
IUUC-Ola-086934	Oryzias latipes	68.02	0.00e+00	666.00
IUUC-Oga-088535	Otolemur garnettii	90.49	0.00e+00	1003.00
IUUC-Oar-089875	Ovis aries	90.11	0.00e+00	978.00
IUUC-Ptr-090541	Pan troglodytes	90.86	0.00e+00	980.00
IUUC-Pan-092416	Papio anubis	90.49	0.00e+00	978.00
IUUC-Psi-092960	Pelodiscus sinensis	89.74	0.00e+00	988.00
IUUC-Pma-094222	Petromyzon marinus	50.54	1.00e-136	479.00
IUUC-Pfo-096930	Poecilia formosa	64.30	0.00e+00	652.00
IUUC-Pab-098659	Pongo abelii	90.67	0.00e+00	980.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.40
IUUC-Pca-100222	Procavia capensis	87.90	0.00e+00	966.00
IUUC-Pva-102387	Pteropus vampyrus	90.11	0.00e+00	974.00
IUUC-Rno-105698	Rattus norvegicus	89.18	0.00e+00	966.00
IUUC-Sha-107234	Sarcophilus harrisii	88.87	0.00e+00	957.00
IUUC-Sar-113698	Sorex araneus	85.07	0.00e+00	875.00
IUUC-Ssc-115985	Sus scrofa	89.37	0.00e+00	988.00
IUUC-Tgu-116676	Taeniopygia guttata	95.90	0.00e+00	1051.00
IUUC-Tru-118441	Takifugu rubripes	59.85	2.00e-152	531.00
IUUC-Tsy-119163	Tarsius syrichta	84.14	0.00e+00	927.00
IUUC-Tni-120436	Tetraodon nigroviridis	66.11	0.00e+00	640.00
IUUC-Tae-124846	Triticum aestivum	32.65	1.70e-01	28.90
IUUC-Tbe-127353	Tupaia belangeri	90.49	0.00e+00	979.00
IUUC-Ttr-128907	Tursiops truncatus	90.49	0.00e+00	959.00
IUUC-Vpa-130140	Vicugna pacos	90.11	0.00e+00	978.00
IUUC-Vvi-131327	Vitis vinifera	43.75	1.00e-01	30.80
IUUC-Xtr-132817	Xenopus tropicalis	79.70	0.00e+00	867.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence