iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-116562

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01042043

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002586.1	ENSTGUT00000002686.1	ENSTGUP00000002658.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.50e-19	68.4	29	91
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.60e-07	28.6	128	157

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           Dv++v gg+ef ah++vLaa+S +F+a+f + l+es+  ++v +++v+pe++  ll+F Ytg++
   Q: 29   DVTVVAGGREFGAHRAVLAAASGYFRAMFGGALRESR-AERVRLHGVEPECLGRLLDFAYTGRV 91
           9************************************.************************97 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkh 30
           + N+l++ +fA+++ cp+L+ aa++f+l+h
   Q: 128  PANALDMQDFAEAFACPELAAAAHRFVLRH 157
           57***************************9 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

AAAAAGEPAH AVSLLRGLSA LRAERSLLDV TVVAGGREFG AHRAVLAAAS GYFRAMFGGA 60
LRESRAERVR LHGVEPECLG RLLDFAYTGR VGRLGPDIAE RLLRAADLLQ FPAVKEACGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGG CGGCGGGAGA ACCGGCACAC GCGGTGTCGC TGCTGCGGGG TCTGAGCGCG 60
CTGCGGGCCG AGCGGAGCCT GCTGGACGTG ACGGTGGTGG CCGGCGGGCG AGAGTTCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	76.00	0.00e+00	773.00
IUUC-Apl-003189	Anas platyrhynchos	96.68	9.00e-160	555.00
IUUC-Ani-009467	Aspergillus nidulans	31.30	1.00e-08	53.10
IUUC-Ame-011774	Astyanax mexicanus	63.69	2.00e-121	428.00
IUUC-Bta-012367	Bos taurus	83.66	0.00e+00	926.00
IUUC-Cja-019501	Callithrix jacchus	79.02	0.00e+00	857.00
IUUC-Cfa-020550	Canis familiaris	83.48	0.00e+00	927.00
IUUC-Cpo-022072	Cavia porcellus	83.39	0.00e+00	906.00
IUUC-Csa-023364	Chlorocebus sabaeus	84.47	0.00e+00	870.00
IUUC-Cin-025253	Ciona intestinalis	42.88	1.00e-138	486.00
IUUC-Csv-025871	Ciona savignyi	43.54	1.00e-141	496.00
IUUC-Dre-028694	Danio rerio	70.04	0.00e+00	808.00
IUUC-Dno-029082	Dasypus novemcinctus	84.25	0.00e+00	821.00
IUUC-Dor-030680	Dipodomys ordii	83.72	0.00e+00	923.00
IUUC-Dse-031222	Dothistroma septosporum	28.38	5.00e-05	41.20
IUUC-Ete-032315	Echinops telfairi	84.39	0.00e+00	821.00
IUUC-Eca-033570	Equus caballus	86.23	2.00e-177	614.00
IUUC-Eeu-035067	Erinaceus europaeus	86.61	2.00e-126	446.00
IUUC-Fca-035663	Felis catus	81.65	4.00e-105	373.00
IUUC-Fal-037103	Ficedula albicollis	99.47	0.00e+00	1055.00
IUUC-Gmo-039420	Gadus morhua	67.02	0.00e+00	775.00
IUUC-Ggr-039934	Gaeumannomyces graminis	32.18	3.00e-09	55.50
IUUC-Gga-040161	Gallus gallus	95.92	0.00e+00	1007.00
IUUC-Gac-041755	Gasterosteus aculeatus	69.95	0.00e+00	802.00
IUUC-Ggo-044899	Gorilla gorilla	83.57	0.00e+00	926.00
IUUC-Hsa-045834	Homo sapiens	83.57	0.00e+00	926.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	83.57	0.00e+00	923.00
IUUC-Lch-050338	Latimeria chalumnae	68.80	0.00e+00	805.00
IUUC-Loc-051780	Lepisosteus oculatus	72.08	0.00e+00	811.00
IUUC-Laf-053725	Loxodonta africana	70.54	0.00e+00	758.00
IUUC-Mcc-055032	Macaca mulatta	84.47	0.00e+00	800.00
IUUC-Meu-056661	Macropus eugenii	88.25	0.00e+00	719.00
IUUC-Mga-059821	Meleagris gallopavo	95.47	4.00e-141	493.00
IUUC-Mdo-062095	Monodelphis domestica	83.84	0.00e+00	798.00
IUUC-Mmu-063138	Mus musculus	85.25	0.00e+00	929.00
IUUC-Mpu-066386	Mustela putorius furo	86.56	3.00e-162	563.00
IUUC-Mlu-067807	Myotis lucifugus	87.54	0.00e+00	629.00
IUUC-Nle-069181	Nomascus leucogenys	81.90	0.00e+00	910.00
IUUC-Opr-070658	Ochotona princeps	83.24	0.00e+00	946.00
IUUC-Ont-072209	Oreochromis niloticus	70.70	0.00e+00	803.00
IUUC-Oan-072861	Ornithorhynchus anatinus	87.62	4.00e-112	396.00
IUUC-Ocu-074631	Oryctolagus cuniculus	74.34	0.00e+00	791.00
IUUC-Ola-087553	Oryzias latipes	68.86	0.00e+00	787.00
IUUC-Oga-088782	Otolemur garnettii	83.57	0.00e+00	924.00
IUUC-Oar-089634	Ovis aries	83.30	0.00e+00	924.00
IUUC-Ptr-091259	Pan troglodytes	86.12	0.00e+00	744.00
IUUC-Pan-091734	Papio anubis	83.75	0.00e+00	928.00
IUUC-Psi-092979	Pelodiscus sinensis	92.32	0.00e+00	1022.00
IUUC-Pma-094459	Petromyzon marinus	52.05	1.00e-115	409.00
IUUC-Pno-094945	Phaeosphaeria nodorum	29.41	2.00e-06	45.40
IUUC-Pfo-097446	Poecilia formosa	69.96	0.00e+00	794.00
IUUC-Pab-098765	Pongo abelii	82.95	0.00e+00	928.00
IUUC-Pva-102730	Pteropus vampyrus	79.93	0.00e+00	876.00
IUUC-Rno-104972	Rattus norvegicus	84.52	0.00e+00	924.00
IUUC-Ssc-115869	Sus scrofa	84.36	0.00e+00	801.00
IUUC-Tru-118490	Takifugu rubripes	69.60	0.00e+00	787.00
IUUC-Tni-119898	Tetraodon nigroviridis	67.95	0.00e+00	758.00
IUUC-Ttr-128976	Tursiops truncatus	85.77	2.00e-125	442.00
IUUC-Xtr-132876	Xenopus tropicalis	71.56	0.00e+00	843.00
IUUC-Xma-133540	Xiphophorus maculatus	70.15	0.00e+00	797.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence