iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020109

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006497

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000016629.3	ENSCAFT00000026342.3	ENSCAFP00000024464.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.50e-14	53.9	418	465

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 418  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 465
           567899*********************998...*************99976 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

PGPWPPSAPL PRAAGPAGLP AAAADGVPQR GSAAGGGGRG GGPSLETNSC SEEELSPGRG 60
GGGGGRLLLQ SPGPELPPVP FPMQDLVPPG RLGRGEQQQP PPPPPPPGPL RPLAGPSRKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGGCCAT GGCCCCCCTC CGCCCCCCTT CCTCGCGCGG CCGGGCCCGC GGGGCTCCCG 60
GCCGCCGCAG CTGATGGTGT TCCGCAACGT GGGTCGGCCG CCGGAGGAGG AGGACGCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	92.84	0.00e+00	652.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	8.00e-73	265.00
IUUC-Aca-004639	Anolis carolinensis	97.28	1.00e-107	381.00
IUUC-Ame-011301	Astyanax mexicanus	69.74	3.00e-130	458.00
IUUC-Bta-013483	Bos taurus	96.89	0.00e+00	689.00
IUUC-Cja-019765	Callithrix jacchus	100.00	6.00e-163	566.00
IUUC-Cpo-021555	Cavia porcellus	95.23	3.00e-177	614.00
IUUC-Csa-023580	Chlorocebus sabaeus	95.65	0.00e+00	651.00
IUUC-Cho-024431	Choloepus hoffmanni	99.21	1.00e-71	263.00
IUUC-Dre-028183	Danio rerio	70.71	8.00e-139	487.00
IUUC-Dno-028858	Dasypus novemcinctus	94.43	0.00e+00	670.00
IUUC-Dor-031071	Dipodomys ordii	79.56	2.00e-113	402.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	2.00e-43	171.00
IUUC-Ete-032928	Echinops telfairi	71.47	4.00e-101	361.00
IUUC-Eca-033250	Equus caballus	93.67	1.00e-176	612.00
IUUC-Eeu-034946	Erinaceus europaeus	91.45	1.00e-52	200.00
IUUC-Fca-036589	Felis catus	98.31	0.00e+00	656.00
IUUC-Fal-037316	Ficedula albicollis	93.07	1.00e-111	395.00
IUUC-Gmo-038552	Gadus morhua	91.26	2.00e-53	200.00
IUUC-Gga-041248	Gallus gallus	96.76	2.00e-107	380.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	1.00e-56	211.00
IUUC-Ggo-045282	Gorilla gorilla	99.69	4.00e-162	563.00
IUUC-Hsa-045926	Homo sapiens	95.41	0.00e+00	650.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	96.13	6.00e-148	517.00
IUUC-Lch-049768	Latimeria chalumnae	71.55	4.00e-147	514.00
IUUC-Loc-051949	Lepisosteus oculatus	74.30	2.00e-129	456.00
IUUC-Laf-053410	Loxodonta africana	98.41	0.00e+00	651.00
IUUC-Mcc-054605	Macaca mulatta	86.49	0.00e+00	629.00
IUUC-Meu-056773	Macropus eugenii	80.19	2.00e-106	378.00
IUUC-Mvi-060489	Microbotryum violaceum	24.37	9.60e+00	24.60
IUUC-Mmr-060927	Microcebus murinus	97.56	0.00e+00	655.00
IUUC-Mdo-061892	Monodelphis domestica	88.50	4.00e-178	617.00
IUUC-Mmu-064246	Mus musculus	96.59	0.00e+00	651.00
IUUC-Mpu-065995	Mustela putorius furo	98.55	0.00e+00	638.00
IUUC-Mlu-067526	Myotis lucifugus	96.18	0.00e+00	678.00
IUUC-Nle-069317	Nomascus leucogenys	97.62	4.00e-163	567.00
IUUC-Ont-072258	Oreochromis niloticus	65.71	3.00e-117	415.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	2.00e-36	142.00
IUUC-Ocu-074577	Oryctolagus cuniculus	93.16	0.00e+00	656.00
IUUC-Oga-088426	Otolemur garnettii	93.92	0.00e+00	646.00
IUUC-Oar-089407	Ovis aries	97.12	0.00e+00	662.00
IUUC-Ptr-091327	Pan troglodytes	98.41	0.00e+00	632.00
IUUC-Pan-092064	Papio anubis	98.67	0.00e+00	644.00
IUUC-Psi-093834	Pelodiscus sinensis	94.36	3.00e-153	534.00
IUUC-Pfo-097100	Poecilia formosa	61.21	1.00e-115	410.00
IUUC-Pab-097695	Pongo abelii	94.50	0.00e+00	630.00
IUUC-Pca-100569	Procavia capensis	90.40	2.00e-169	589.00
IUUC-Pva-102784	Pteropus vampyrus	94.66	0.00e+00	641.00
IUUC-Ptt-103775	Puccinia triticina	38.46	2.00e+00	28.10
IUUC-Rno-105485	Rattus norvegicus	96.84	0.00e+00	652.00
IUUC-Sha-106720	Sarcophilus harrisii	94.72	2.00e-173	602.00
IUUC-Sar-112975	Sorex araneus	84.59	4.00e-128	450.00
IUUC-Ssc-116369	Sus scrofa	95.48	0.00e+00	653.00
IUUC-Tgu-116867	Taeniopygia guttata	87.15	1.00e-124	439.00
IUUC-Tru-117562	Takifugu rubripes	82.21	3.00e-100	358.00
IUUC-Tsy-118999	Tarsius syrichta	93.71	1.00e-145	509.00
IUUC-Tni-120793	Tetraodon nigroviridis	68.62	2.00e-128	452.00
IUUC-Tbe-127671	Tupaia belangeri	99.07	6.00e-128	450.00
IUUC-Ttr-128491	Tursiops truncatus	83.65	1.00e-127	449.00
IUUC-Vpa-130104	Vicugna pacos	91.50	4.00e-176	610.00
IUUC-Xtr-132507	Xenopus tropicalis	80.90	1.00e-144	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence