iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033537

Ensembl Protein ID

ENSECAP00000001260.1

UniProt Accession

F6VDB9; F6VDB9_HORSE

Protein Name

Uncharacterized protein

Gene Name

SHARPIN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000001400.1	ENSECAT00000001684.1	ENSECAP00000001260.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.90e-13	49.8	339	367
ULD/UDP/UBQ/UBQ_Other	6.90e-14	51.7	220	281

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRgc 30
           +++W+C++CTf+N+P++++CemCs++R+c
   Q: 339  QPGWSCPSCTFINAPSRPGCEMCSTQRPC 367
           689*************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
           qvtv+++ +s + +l+v+p++t+a L+e++++++g+pp+ qr+++ G++L  + ++La+yg++
   Q: 220  QVTVEDAASSaHVSLQVHPHCTIAALQEQVFSEFGFPPAVQRWVI-GRCLcVPECSLASYGIQ 281
           89*******************************************.**************996 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MATPAGGTLV PDPDSAMVLL AVHVAVRALG AGPDTEAQLR RLQLSADPER PGRFRLELLG 60
AGPGAVNLEW PLESVSYTVR GPSQHELQPP PGGPGTLSLH FPNPQEAQRW AALVRGATVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACTC CAGCGGGCGG CACGTTAGTA CCGGACCCGG ACTCGGCCAT GGTGCTCCTT 60
GCCGTACACG TCGCGGTGAG GGCGCTGGGC GCGGGGCCGG ACACCGAGGC GCAGCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR031912--Sharpin_PH
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF16764--Sharpin_PH
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000111	Aegilops tauschii	35.29	6.10e-02	31.60
IUUC-Aml-001223	Ailuropoda melanoleuca	85.79	2.00e-146	511.00
IUUC-Apl-004151	Anas platyrhynchos	68.09	3.00e-17	79.30
IUUC-Bta-012948	Bos taurus	86.77	4.00e-154	537.00
IUUC-Cja-019031	Callithrix jacchus	80.28	5.00e-133	467.00
IUUC-Cfa-020863	Canis familiaris	80.11	7.00e-127	446.00
IUUC-Cpo-022499	Cavia porcellus	74.06	7.00e-127	446.00
IUUC-Csa-023641	Chlorocebus sabaeus	80.11	1.00e-133	469.00
IUUC-Dre-027612	Danio rerio	39.72	2.00e-44	172.00
IUUC-Dno-029459	Dasypus novemcinctus	67.15	2.00e-64	238.00
IUUC-Dor-030914	Dipodomys ordii	62.22	1.00e-88	319.00
IUUC-Ete-032940	Echinops telfairi	71.07	3.00e-106	378.00
IUUC-Eeu-035176	Erinaceus europaeus	70.41	6.00e-68	251.00
IUUC-Fca-035971	Felis catus	87.27	2.00e-138	485.00
IUUC-Fal-037440	Ficedula albicollis	63.16	5.00e-10	55.50
IUUC-Gmo-039219	Gadus morhua	38.78	6.00e-53	201.00
IUUC-Gga-040198	Gallus gallus	43.53	3.00e-30	125.00
IUUC-Ggo-044678	Gorilla gorilla	80.55	4.00e-134	470.00
IUUC-Hsa-046578	Homo sapiens	81.67	7.00e-140	489.00
IUUC-Itr-047913	Ictidomys tridecemlineatus	75.96	9.00e-142	496.00
IUUC-Mcc-055686	Macaca mulatta	75.96	9.00e-135	473.00
IUUC-Meu-055912	Macropus eugenii	54.13	1.00e-68	253.00
IUUC-Mmr-060584	Microcebus murinus	77.32	5.00e-142	497.00
IUUC-Mdo-062191	Monodelphis domestica	57.78	1.00e-86	313.00
IUUC-Mmu-063740	Mus musculus	71.47	8.00e-116	410.00
IUUC-Mpu-066878	Mustela putorius furo	83.89	6.00e-120	423.00
IUUC-Mlu-067878	Myotis lucifugus	84.30	9.00e-150	522.00
IUUC-Nle-069748	Nomascus leucogenys	80.89	6.00e-127	446.00
IUUC-Ont-072270	Oreochromis niloticus	38.33	9.00e-55	207.00
IUUC-Oba-075102	Oryza barthii	42.22	1.00e-03	37.40
IUUC-Obr-076087	Oryza brachyantha	51.52	2.00e-04	38.90
IUUC-Ogl-077291	Oryza glaberrima	42.22	1.00e-03	37.40
IUUC-Oin-079800	Oryza indica	44.68	4.00e-04	38.90
IUUC-Ome-081262	Oryza meridionalis	42.22	2.00e-03	36.60
IUUC-Oni-082829	Oryza nivara	44.68	4.00e-04	38.90
IUUC-Opu-083275	Oryza punctata	40.91	5.00e-03	35.40
IUUC-Oru-084564	Oryza rufipogon	42.22	3.00e-03	35.80
IUUC-Osa-085600	Oryza sativa	42.22	3.00e-03	35.80
IUUC-Oga-088300	Otolemur garnettii	77.34	2.00e-144	505.00
IUUC-Oar-089549	Ovis aries	86.24	6.00e-157	546.00
IUUC-Ptr-090961	Pan troglodytes	81.33	9.00e-127	446.00
IUUC-Pan-092687	Papio anubis	82.79	1.00e-136	479.00
IUUC-Pma-094669	Petromyzon marinus	37.89	3.00e-29	121.00
IUUC-Pab-097872	Pongo abelii	77.15	8.00e-124	436.00
IUUC-Pca-100363	Procavia capensis	72.86	1.00e-72	266.00
IUUC-Pva-102595	Pteropus vampyrus	86.01	5.00e-137	480.00
IUUC-Rno-105856	Rattus norvegicus	71.31	1.00e-112	399.00
IUUC-Sha-106838	Sarcophilus harrisii	54.62	8.00e-78	284.00
IUUC-Sar-113611	Sorex araneus	67.02	2.00e-26	112.00
IUUC-Ssc-116263	Sus scrofa	84.57	2.00e-154	538.00
IUUC-Tru-118089	Takifugu rubripes	41.80	1.00e-62	233.00
IUUC-Tni-120004	Tetraodon nigroviridis	42.32	2.00e-49	189.00
IUUC-Tbe-127471	Tupaia belangeri	66.96	1.00e-104	373.00
IUUC-Ttr-128534	Tursiops truncatus	80.95	1.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence