iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cgl-026526

Ensembl Protein ID

ELA37702

UniProt Accession

L2GGE0; L2GGE0_COLGN

Genbank Protein ID

ELA37702.1

Protein Name

Ubiquitin-protein ligase

Genbank Nucleotide ID

KB020351

Gene Name

CGGC5_2938

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CGGC5_2938	ELA37702	ELA37702

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-80	271.1	856	1200

Active Site

Position(s)	Description	Evidence
1169	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklll 101
           +d+kk l++ f+gEegld+gG+++e++ ll++e++npd g+f y+e+++ + + np+s+    e  + + ++G+++g+a++++ +ld+ l+++ +++ll
   Q: 856  EDIKKGLRIVFKGEEGLDAGGLKKEWFLLLVREVFNPDHGMFIYDEDSQFC-YFNPNSF----ETSDQYFLVGVVMGLAIYNSTILDVALPPFAFRKLL 949
           6899**************************************999975544.6788888....34555559***************************9 PP
   S: 102  gk................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
                             +++ledl+e  p l+  l +++e  + d+ee+ ++l f v+ e++g ++++ L+pgGe+  Vtn+Nk eYv+l+v y l++
   Q: 950  ASapssstgpsahprpsmNYTLEDLAEYRPRLAAGLRQLLEF-DGDVEET-FQLDFVVDVEKYGIITQVPLCPGGERKAVTNANKWEYVNLYVRYLLET 1046
           8888888888888777777*********************99.7799997.************************************************ PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky....kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgG 278
            +++q+e f++Gf++v+  + lslF++ee+ell+ G+ + +dv++l+  ++y    ++     +p+i wFwe+++e + +e++++L F+Tg++r+P+ G
   Q: 1047 AVTRQFEPFKRGFYTVCGGNALSLFRPEEIELLVRGSdTALDVDALRGVAEYdnwgTKTPDGVEPVIGWFWETFKEATPDEQRKLLSFITGTDRVPAMG 1145
           *************************************99*************544333334457999******************************** PP
   S: 279  faelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            a l+ +++++ +  +++r+P + TCfn+L L +Y s e l+++L +A++e++gF+l
   Q: 1146 AALLPIKITCLGE--DENRYPIARTCFNMLSLRRYGSRERLEQMLWTAVHESEGFGL 1200
           *****99999888..88**************************************98 PP

Organism

Colletotrichum gloeosporioides

Protein Sequence
(Fasta)

MAPWSQRHAP PLRPPPLRRP SADVISRIHS HSSLTAPPGQ LGRLPDYVLL DNSQLHAADE 60
SSSESDFHPR RPRRPTHSRS MSHPFPALFS KKKRPEPTTY ETDSDSDDAP VMTKPLGNTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCTT GGTCGCAACG TCATGCTCCA CCTCTTCGTC CTCCTCCTCT CCGTCGCCCT 60
TCCGCCGATG TTATCTCTCG GATACACAGC CACTCCTCTT TAACTGCACC GCCTGGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	32.31	7.00e-104	369.00
IUUC-Atr-003144	Amborella trichopoda	37.90	4.00e-87	313.00
IUUC-Apl-003589	Anas platyrhynchos	31.95	5.00e-94	337.00
IUUC-Aca-004350	Anolis carolinensis	41.10	2.00e-97	348.00
IUUC-Ago-007908	Ashbya gossypii	36.26	1.00e-89	322.00
IUUC-Acl-008288	Aspergillus clavatus	46.11	0.00e+00	949.00
IUUC-Afl-008402	Aspergillus flavus	56.26	0.00e+00	741.00
IUUC-Afu-008762	Aspergillus fumigatus	47.06	0.00e+00	971.00
IUUC-Ani-009176	Aspergillus nidulans	58.37	0.00e+00	716.00
IUUC-Ang-009791	Aspergillus niger	46.44	0.00e+00	877.00
IUUC-Aor-009921	Aspergillus oryzae	59.63	0.00e+00	708.00
IUUC-Ate-010295	Aspergillus terreus	52.40	0.00e+00	863.00
IUUC-Ame-011166	Astyanax mexicanus	38.08	6.00e-81	293.00
IUUC-Bgr-011981	Blumeria graminis	48.89	0.00e+00	1052.00
IUUC-Bta-012945	Bos taurus	42.30	1.00e-101	362.00
IUUC-Cel-018150	Caenorhabditis elegans	31.14	2.00e-53	202.00
IUUC-Cja-019263	Callithrix jacchus	42.17	3.00e-100	358.00
IUUC-Cfa-020486	Canis familiaris	32.49	7.00e-105	372.00
IUUC-Cpo-021755	Cavia porcellus	32.57	1.00e-104	372.00
IUUC-Cre-022963	Chlamydomonas reinhardtii	40.48	9.00e-65	238.00
IUUC-Csa-023814	Chlorocebus sabaeus	42.03	6.00e-90	323.00
IUUC-Cho-024325	Choloepus hoffmanni	36.94	4.00e-66	244.00
IUUC-Cin-025643	Ciona intestinalis	35.13	5.00e-68	251.00
IUUC-Csv-026282	Ciona savignyi	35.67	1.00e-62	233.00
IUUC-Cme-027151	Cyanidioschyzon merolae	37.53	7.00e-80	290.00
IUUC-Dre-028551	Danio rerio	41.02	3.00e-95	340.00
IUUC-Dno-029497	Dasypus novemcinctus	42.23	4.00e-101	360.00
IUUC-Dor-030867	Dipodomys ordii	35.95	2.00e-75	275.00
IUUC-Dse-031239	Dothistroma septosporum	49.61	0.00e+00	848.00
IUUC-Dme-032103	Drosophila melanogaster	34.68	1.00e-68	253.00
IUUC-Ete-032902	Echinops telfairi	33.99	3.00e-92	331.00
IUUC-Eca-033678	Equus caballus	32.49	2.00e-105	375.00
IUUC-Eeu-035109	Erinaceus europaeus	37.19	2.00e-69	255.00
IUUC-Fca-035590	Felis catus	32.35	2.00e-105	375.00
IUUC-Fal-037123	Ficedula albicollis	31.96	4.00e-86	310.00
IUUC-Fox-037941	Fusarium oxysporum	58.72	0.00e+00	1260.00
IUUC-Fso-038388	Fusarium solani	56.79	0.00e+00	1257.00
IUUC-Gmo-039553	Gadus morhua	40.44	1.00e-83	302.00
IUUC-Ggr-040110	Gaeumannomyces graminis	52.91	0.00e+00	1110.00
IUUC-Gga-040406	Gallus gallus	31.91	1.00e-97	349.00
IUUC-Gac-042141	Gasterosteus aculeatus	38.37	1.00e-94	339.00
IUUC-Ggo-045504	Gorilla gorilla	42.30	3.00e-101	361.00
IUUC-Hsa-045786	Homo sapiens	42.30	2.00e-101	361.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	38.31	6.00e-77	280.00
IUUC-Kpa-049152	Komagataella pastoris	33.24	5.00e-97	347.00
IUUC-Lch-049824	Latimeria chalumnae	43.52	5.00e-86	310.00
IUUC-Loc-052173	Lepisosteus oculatus	31.73	3.00e-101	361.00
IUUC-Laf-054017	Loxodonta africana	42.14	5.00e-100	357.00
IUUC-Mcc-055713	Macaca mulatta	42.08	1.00e-100	359.00
IUUC-Meu-056061	Macropus eugenii	38.08	2.00e-76	278.00
IUUC-Mor-057045	Magnaporthe oryzae	53.56	0.00e+00	1137.00
IUUC-Mla-059187	Melampsora laricipopulina	42.80	3.00e-91	327.00
IUUC-Mga-059884	Meleagris gallopavo	41.55	4.00e-89	320.00
IUUC-Mmr-061344	Microcebus murinus	32.31	4.00e-105	374.00
IUUC-Mdo-062653	Monodelphis domestica	43.23	7.00e-102	363.00
IUUC-Mmu-063775	Mus musculus	41.52	5.00e-101	360.00
IUUC-Mpu-066069	Mustela putorius furo	32.22	6.00e-104	369.00
IUUC-Mlu-067925	Myotis lucifugus	42.52	2.00e-102	365.00
IUUC-Nfi-068439	Neosartorya fischeri	51.53	0.00e+00	887.00
IUUC-Ncr-068903	Neurospora crassa	53.72	0.00e+00	1090.00
IUUC-Nle-070046	Nomascus leucogenys	32.18	2.00e-103	368.00
IUUC-Opr-070570	Ochotona princeps	33.63	2.00e-58	219.00
IUUC-Ont-072126	Oreochromis niloticus	31.50	2.00e-95	341.00
IUUC-Oan-072933	Ornithorhynchus anatinus	42.51	3.00e-100	357.00
IUUC-Ocu-073800	Oryctolagus cuniculus	41.87	3.00e-100	357.00
IUUC-Ola-086988	Oryzias latipes	32.13	1.00e-97	348.00
IUUC-Oga-088117	Otolemur garnettii	42.08	3.00e-100	357.00
IUUC-Oar-089371	Ovis aries	42.30	2.00e-101	361.00
IUUC-Ptr-090551	Pan troglodytes	42.30	1.00e-101	362.00
IUUC-Pan-092067	Papio anubis	42.08	2.00e-100	358.00
IUUC-Psi-092963	Pelodiscus sinensis	42.20	4.00e-98	350.00
IUUC-Pma-094643	Petromyzon marinus	37.75	8.00e-80	290.00
IUUC-Ppa-095354	Physcomitrella patens	40.92	7.00e-94	337.00
IUUC-Pfo-096562	Poecilia formosa	30.72	1.00e-94	339.00
IUUC-Pab-098680	Pongo abelii	42.08	1.00e-100	359.00
IUUC-Pca-100869	Procavia capensis	37.64	7.00e-76	276.00
IUUC-Pva-102219	Pteropus vampyrus	39.95	5.00e-81	293.00
IUUC-Pgr-103315	Puccinia graminis	40.45	2.00e-98	352.00
IUUC-Ptt-103736	Puccinia triticina	41.00	7.00e-97	347.00
IUUC-Rno-105270	Rattus norvegicus	41.61	5.00e-101	360.00
IUUC-Sce-106306	Saccharomyces cerevisiae	30.14	6.00e-76	277.00
IUUC-Sha-106819	Sarcophilus harrisii	33.47	4.00e-109	387.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	35.29	3.00e-55	207.00
IUUC-Spo-108271	Schizosaccharomyces pombe	35.74	5.00e-105	374.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	56.65	0.00e+00	956.00
IUUC-Smo-108858	Selaginella moellendorffii	40.97	4.00e-85	307.00
IUUC-Sar-113134	Sorex araneus	37.77	6.00e-85	306.00
IUUC-Ssc-115441	Sus scrofa	42.21	1.00e-101	362.00
IUUC-Tgu-117166	Taeniopygia guttata	32.54	5.00e-94	337.00
IUUC-Tru-118368	Takifugu rubripes	37.69	9.00e-80	290.00
IUUC-Tsy-118898	Tarsius syrichta	37.83	1.00e-80	292.00
IUUC-Tni-120143	Tetraodon nigroviridis	37.91	5.00e-80	290.00
IUUC-Tre-122108	Trichoderma reesei	56.17	0.00e+00	1157.00
IUUC-Tvi-122644	Trichoderma virens	56.70	0.00e+00	1179.00
IUUC-Tme-127004	Tuber melanosporum	47.31	0.00e+00	762.00
IUUC-Tbe-127640	Tupaia belangeri	37.41	6.00e-67	247.00
IUUC-Ttr-128352	Tursiops truncatus	40.31	3.00e-93	334.00
IUUC-Vda-129969	Verticillium dahliae	59.61	0.00e+00	1266.00
IUUC-Vpa-130448	Vicugna pacos	33.47	2.00e-69	256.00
IUUC-Xtr-132594	Xenopus tropicalis	40.31	2.00e-87	315.00
IUUC-Xma-134157	Xiphophorus maculatus	31.39	6.00e-89	320.00
IUUC-Yli-134470	Yarrowia lipolytica	38.07	4.00e-96	344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence