iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105139

Ensembl Protein ID

ENSRNOP00000024786.3

UniProt Accession

G3V8D3; G3V8D3_RAT

Genbank Protein ID

EDL93526.1

Protein Name

BTB (POZ) domain containing 14A; Nucleus accumbens-associated protein 2

Genbank Nucleotide ID

AABR07072841

Gene Name

Nacc2; Btbd14a; rCG_45787

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000018231.6	ENSRNOT00000024786.6	ENSRNOP00000024786.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.40e-16	58.7	30	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv +vv+g+ f+ah++vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytgkl++
   Q: 30   CDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGN-----SKSAFELPGtVPPACFQQILSFCYTGKLTM 92
           8*****************************774.....46778***88*****************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS 60
GNSKSAFELP GTVPPACFQQ ILSFCYTGKL TMAASEQLVV MYTAGFLQIQ HIVERGTDLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGACGCCG GAGCACTTCC TGCCGCGGGC GGCGCCGCAG CTGCCCAGGC CGGACTGGGC 60
CGGGTGCCCG CAGGTACGGC CAACTTGGCG CGCGTCGCGC CGTTTCCGCC GCGGGCCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

KEGG

rno:296583

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	87.72	0.00e+00	835.00
IUUC-Apl-004203	Anas platyrhynchos	79.56	0.00e+00	947.00
IUUC-Ame-011046	Astyanax mexicanus	56.20	4.00e-147	514.00
IUUC-Bta-012908	Bos taurus	90.89	0.00e+00	957.00
IUUC-Cja-019140	Callithrix jacchus	90.14	0.00e+00	1034.00
IUUC-Cfa-020493	Canis familiaris	86.71	5.00e-168	583.00
IUUC-Cpo-022399	Cavia porcellus	89.66	0.00e+00	1056.00
IUUC-Csa-024135	Chlorocebus sabaeus	90.15	0.00e+00	1018.00
IUUC-Dre-027761	Danio rerio	70.45	2.00e-81	296.00
IUUC-Dno-029271	Dasypus novemcinctus	77.63	0.00e+00	739.00
IUUC-Ete-032427	Echinops telfairi	83.59	0.00e+00	896.00
IUUC-Eca-033986	Equus caballus	89.13	0.00e+00	1012.00
IUUC-Eeu-035211	Erinaceus europaeus	88.25	0.00e+00	987.00
IUUC-Fca-035733	Felis catus	87.78	0.00e+00	907.00
IUUC-Fal-037348	Ficedula albicollis	81.49	0.00e+00	947.00
IUUC-Gmo-039529	Gadus morhua	81.46	3.00e-93	335.00
IUUC-Gga-040405	Gallus gallus	82.45	0.00e+00	978.00
IUUC-Gac-041308	Gasterosteus aculeatus	68.79	1.00e-173	602.00
IUUC-Ggo-044687	Gorilla gorilla	71.07	0.00e+00	781.00
IUUC-Hsa-045955	Homo sapiens	88.79	0.00e+00	999.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	92.88	0.00e+00	1028.00
IUUC-Lch-049615	Latimeria chalumnae	75.89	0.00e+00	915.00
IUUC-Loc-051881	Lepisosteus oculatus	69.81	0.00e+00	685.00
IUUC-Lma-053325	Leptosphaeria maculans	36.84	1.00e-06	47.00
IUUC-Laf-054170	Loxodonta africana	85.91	0.00e+00	948.00
IUUC-Mga-059627	Meleagris gallopavo	81.60	0.00e+00	972.00
IUUC-Mdo-063014	Monodelphis domestica	84.70	9.00e-178	616.00
IUUC-Mmu-063897	Mus musculus	97.78	0.00e+00	1133.00
IUUC-Mpu-066806	Mustela putorius furo	87.10	0.00e+00	927.00
IUUC-Nle-069114	Nomascus leucogenys	89.50	0.00e+00	922.00
IUUC-Opr-071127	Ochotona princeps	95.35	6.00e-72	265.00
IUUC-Ont-071693	Oreochromis niloticus	68.71	6.00e-175	607.00
IUUC-Oan-073510	Ornithorhynchus anatinus	85.08	0.00e+00	1015.00
IUUC-Ola-086572	Oryzias latipes	65.18	0.00e+00	644.00
IUUC-Oga-088653	Otolemur garnettii	87.73	0.00e+00	1018.00
IUUC-Oar-089811	Ovis aries	87.35	0.00e+00	798.00
IUUC-Ptr-090703	Pan troglodytes	88.27	0.00e+00	983.00
IUUC-Pan-092388	Papio anubis	89.86	0.00e+00	1031.00
IUUC-Psi-093786	Pelodiscus sinensis	82.28	0.00e+00	986.00
IUUC-Pma-094566	Petromyzon marinus	49.70	3.00e-107	382.00
IUUC-Pno-095029	Phaeosphaeria nodorum	29.11	2.00e-05	42.40
IUUC-Pfo-096554	Poecilia formosa	64.26	0.00e+00	628.00
IUUC-Pca-101090	Procavia capensis	86.51	0.00e+00	959.00
IUUC-Ppe-101171	Prunus persica	39.19	4.00e-06	46.60
IUUC-Pva-102843	Pteropus vampyrus	87.27	0.00e+00	977.00
IUUC-Sha-107545	Sarcophilus harrisii	85.37	0.00e+00	1003.00
IUUC-Tgu-117401	Taeniopygia guttata	81.43	0.00e+00	959.00
IUUC-Tru-118080	Takifugu rubripes	68.07	3.00e-168	584.00
IUUC-Tni-120321	Tetraodon nigroviridis	64.89	4.00e-170	590.00
IUUC-Ttr-128369	Tursiops truncatus	92.34	0.00e+00	716.00
IUUC-Xtr-131793	Xenopus tropicalis	77.44	1.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence