iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035371

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02089114

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008031.2	ENSFCAT00000008032.2	ENSFCAP00000007439.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-08	34.2	27	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk  p+++pCgH f+ +Cl + w     ++ +  +CP Cr
   Q: 27   CSICLEHFKV-PVTTPCGHNFCSSCLdETW----AVQEPPYLCPQCR 68
           ********88.*******************....999*********8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

ARSASASRPV PRSAMAELVP LAEELSCSIC LEHFKVPVTT PCGHNFCSSC LDETWAVQEP 60
PYLCPQCRAS YQERPQLHKN TVLCAVVEQF LQAEVARVAP SPPDGCTPPA RAAEPSPPCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTGTGGG GCGGCCGCGC GGCGTTCGCG CCCGAAGTGC CAGCGCGTCT CGTCCGGTCC 60
CCAGGAGCGC CATGGCGGAG CTGGTCCCCC TGGCCGAGGA GCTGTCGTGC TCCATCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	81.92	0.00e+00	1036.00
IUUC-Apl-004101	Anas platyrhynchos	49.06	1.00e-168	586.00
IUUC-Aca-005025	Anolis carolinensis	47.96	2.00e-169	588.00
IUUC-Bta-012735	Bos taurus	73.63	0.00e+00	919.00
IUUC-Cja-019996	Callithrix jacchus	68.41	2.00e-175	608.00
IUUC-Cfa-020466	Canis familiaris	81.50	0.00e+00	1043.00
IUUC-Cpo-021737	Cavia porcellus	67.19	0.00e+00	847.00
IUUC-Csa-023217	Chlorocebus sabaeus	76.89	0.00e+00	953.00
IUUC-Cho-024346	Choloepus hoffmanni	50.00	6.00e-70	257.00
IUUC-Dno-030082	Dasypus novemcinctus	72.51	0.00e+00	927.00
IUUC-Dor-030335	Dipodomys ordii	50.87	1.00e-119	423.00
IUUC-Ete-032923	Echinops telfairi	68.03	0.00e+00	773.00
IUUC-Eca-033411	Equus caballus	73.38	0.00e+00	938.00
IUUC-Eeu-034656	Erinaceus europaeus	73.40	2.00e-161	561.00
IUUC-Fal-037008	Ficedula albicollis	47.33	3.00e-161	561.00
IUUC-Gmo-038668	Gadus morhua	35.28	8.00e-106	377.00
IUUC-Gga-040608	Gallus gallus	47.74	9.00e-161	560.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.27	3.00e-113	402.00
IUUC-Ggo-044518	Gorilla gorilla	77.17	0.00e+00	928.00
IUUC-Hsa-045828	Homo sapiens	77.60	0.00e+00	954.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	66.48	5.00e-133	468.00
IUUC-Lch-050478	Latimeria chalumnae	37.89	1.00e-125	443.00
IUUC-Loc-052864	Lepisosteus oculatus	36.31	1.00e-114	407.00
IUUC-Laf-054325	Loxodonta africana	77.57	4.00e-167	580.00
IUUC-Mcc-054920	Macaca mulatta	77.20	0.00e+00	954.00
IUUC-Meu-056367	Macropus eugenii	70.29	6.00e-72	265.00
IUUC-Mga-059975	Meleagris gallopavo	48.73	2.00e-162	565.00
IUUC-Mmr-060748	Microcebus murinus	75.51	0.00e+00	920.00
IUUC-Mdo-062904	Monodelphis domestica	58.51	0.00e+00	690.00
IUUC-Mmu-063891	Mus musculus	68.97	0.00e+00	882.00
IUUC-Mpu-066473	Mustela putorius furo	80.28	0.00e+00	1038.00
IUUC-Mlu-068185	Myotis lucifugus	71.99	0.00e+00	907.00
IUUC-Nle-070177	Nomascus leucogenys	76.81	0.00e+00	952.00
IUUC-Opr-070558	Ochotona princeps	59.12	2.00e-141	495.00
IUUC-Ont-071368	Oreochromis niloticus	36.33	4.00e-109	388.00
IUUC-Ocu-074461	Oryctolagus cuniculus	68.91	2.00e-150	526.00
IUUC-Ola-087394	Oryzias latipes	27.29	2.00e-56	213.00
IUUC-Oga-088937	Otolemur garnettii	68.60	0.00e+00	857.00
IUUC-Oar-089781	Ovis aries	70.85	0.00e+00	629.00
IUUC-Ptr-090771	Pan troglodytes	77.60	0.00e+00	937.00
IUUC-Pan-092830	Papio anubis	77.20	0.00e+00	956.00
IUUC-Psi-093664	Pelodiscus sinensis	50.00	3.00e-174	605.00
IUUC-Pma-094147	Petromyzon marinus	26.59	9.00e-57	214.00
IUUC-Pfo-096528	Poecilia formosa	35.87	5.00e-117	414.00
IUUC-Pab-097588	Pongo abelii	77.13	0.00e+00	947.00
IUUC-Pca-100890	Procavia capensis	70.19	0.00e+00	846.00
IUUC-Pva-102314	Pteropus vampyrus	79.28	0.00e+00	952.00
IUUC-Pgr-103377	Puccinia graminis	37.50	2.00e-05	43.90
IUUC-Ptt-103758	Puccinia triticina	31.52	2.00e-05	42.70
IUUC-Rno-105234	Rattus norvegicus	66.31	0.00e+00	848.00
IUUC-Sce-106362	Saccharomyces cerevisiae	44.93	6.00e-10	58.50
IUUC-Sha-106807	Sarcophilus harrisii	54.51	0.00e+00	663.00
IUUC-Sar-113283	Sorex araneus	58.35	2.00e-131	461.00
IUUC-Ssc-115878	Sus scrofa	82.40	1.00e-105	375.00
IUUC-Tgu-117026	Taeniopygia guttata	44.78	5.00e-126	444.00
IUUC-Tru-117794	Takifugu rubripes	34.53	2.00e-98	353.00
IUUC-Tbe-127580	Tupaia belangeri	70.34	8.00e-146	509.00
IUUC-Ttr-128648	Tursiops truncatus	71.76	0.00e+00	634.00
IUUC-Vpa-130254	Vicugna pacos	83.52	4.00e-90	325.00
IUUC-Xtr-132892	Xenopus tropicalis	40.69	3.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence