iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071821

Ensembl Protein ID

ENSONIP00000004105.1

UniProt Accession

I3J5G5; I3J5G5_ORENI

Genbank Protein ID

ENSONIP00000004105

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01013942

Gene Name

wdsub1; LOC100694862

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000003270.1	ENSONIT00000004106.1	ENSONIP00000004105.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-34	116.7	279	312
E3 activity/RING/U-box	9.70e-22	77.3	401	473
UBD/Beta-Prp	6.60e-52	176.9	5	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+  vt++af ++ +l+++Gs D+t+ +W+l +g
   Q: 279  HERYVTACAFsPTsPLIATGSMDKTVNIWRLEDG 312
           999********777****************9988 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp...sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +p+eflCpI+ elM++Pv+++   +G++y++++Ie w++++++++P+t+ pl  + l+Pn+tl+  i +w  +
   Q: 401  IPDEFLCPITRELMKEPVIAAvqtDGYSYEKEAIESWISTKNRSSPMTNLPLLTTLLTPNHTLKMAIGRWKTS 473
           8*****************9877679*********************************************876 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           i+tl++h+++v    +f    +llat s d+t++++d+++ +   ++ l gh  +v +++fs  g++l+++s+D+t  +w++ +g++  
   Q: 5    ICTLQHHQDDVNW-CAF--AAKLLATCSGDKTLRIYDARDFSElpFSPLTGHGYTVHCCCFSACGQFLASCSTDATTVIWSMVSGEIEA 90
           7999999998877.677..79*******************777899******************************************* PP
   S: 89   tlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +l+    + v+ ++fsp++ +lvsG +d t+ +wd +++q  + t +++d +    +++p ++++++Gs+ + +rlWdl++++l  +  
   Q: 91   VLEhPGRSPVRICAFSPDSLHLVSGASDGTLALWDFPSRQLRR-TGAVNDTTMVACSFSPCSQMFMTGSTYGDLRLWDLRMNQLHAEKN 178
           *99334678*********************************9.******999999****99***********************9998 PP
   S: 177  gghtdsvyslsfdsng........kelvsgsldgtvklwdlq 210
             h+  v + +f ++         ++++s+++d+ +k+w + 
   Q: 179  A-HDLGVSCCTFAPSIlsggqvvqFRVASCGQDSLLKIWAIN 219
           7.*********9998799999******************986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTSLICTLQH HQDDVNWCAF AAKLLATCSG DKTLRIYDAR DFSELPFSPL TGHGYTVHCC 60
CFSACGQFLA SCSTDATTVI WSMVSGEIEA VLEHPGRSPV RICAFSPDSL HLVSGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGCCGCA TTACGTCATG GTCAGGTGAT TGACGAGGAA GTAAACAACT CCTAAGAGAA 60
GAGACATCTC GACGGGGAAA GGTGAGGAGA CGTTACACGT TACATTACAA CCAGATTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	57.74	8.00e-152	530.00
IUUC-Apl-003529	Anas platyrhynchos	58.02	9.00e-148	516.00
IUUC-Aca-004257	Anolis carolinensis	55.83	2.00e-147	516.00
IUUC-Ame-011357	Astyanax mexicanus	62.08	1.00e-154	539.00
IUUC-Bta-013032	Bos taurus	57.38	1.00e-149	523.00
IUUC-Cja-018743	Callithrix jacchus	57.32	5.00e-150	524.00
IUUC-Cfa-021197	Canis familiaris	57.32	1.00e-151	529.00
IUUC-Cpo-022279	Cavia porcellus	57.11	1.00e-149	523.00
IUUC-Csa-023954	Chlorocebus sabaeus	57.74	1.00e-150	526.00
IUUC-Cho-025083	Choloepus hoffmanni	44.95	3.00e-78	285.00
IUUC-Dre-028087	Danio rerio	71.84	0.00e+00	678.00
IUUC-Dno-028919	Dasypus novemcinctus	57.11	1.00e-149	523.00
IUUC-Dor-031112	Dipodomys ordii	57.95	4.00e-151	528.00
IUUC-Eca-033254	Equus caballus	57.02	2.00e-152	532.00
IUUC-Eeu-034545	Erinaceus europaeus	57.11	3.00e-146	511.00
IUUC-Fca-035482	Felis catus	57.74	3.00e-151	528.00
IUUC-Fal-036976	Ficedula albicollis	48.02	6.00e-105	374.00
IUUC-Gmo-039213	Gadus morhua	72.63	0.00e+00	665.00
IUUC-Gga-040561	Gallus gallus	57.11	3.00e-144	504.00
IUUC-Gac-041471	Gasterosteus aculeatus	85.05	0.00e+00	768.00
IUUC-Ggo-045503	Gorilla gorilla	56.90	6.00e-150	524.00
IUUC-Hsa-045910	Homo sapiens	56.90	3.00e-149	521.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	54.50	1.00e-115	409.00
IUUC-Loc-052307	Lepisosteus oculatus	65.61	0.00e+00	654.00
IUUC-Laf-053587	Loxodonta africana	57.95	1.00e-151	529.00
IUUC-Mcc-055679	Macaca mulatta	57.11	1.00e-149	523.00
IUUC-Meu-055962	Macropus eugenii	49.37	3.00e-114	405.00
IUUC-Mga-059652	Meleagris gallopavo	57.11	2.00e-146	512.00
IUUC-Mmr-060943	Microcebus murinus	56.13	2.00e-142	498.00
IUUC-Mdo-062592	Monodelphis domestica	56.94	2.00e-147	515.00
IUUC-Mmu-063577	Mus musculus	57.62	5.00e-149	521.00
IUUC-Mpu-066422	Mustela putorius furo	57.74	6.00e-151	527.00
IUUC-Mlu-067250	Myotis lucifugus	57.53	2.00e-149	521.00
IUUC-Nle-069517	Nomascus leucogenys	57.32	6.00e-150	524.00
IUUC-Opr-070776	Ochotona princeps	59.07	2.00e-153	535.00
IUUC-Oan-073706	Ornithorhynchus anatinus	57.38	3.00e-149	521.00
IUUC-Ocu-074766	Oryctolagus cuniculus	53.73	8.00e-135	473.00
IUUC-Ola-086531	Oryzias latipes	85.23	0.00e+00	796.00
IUUC-Oga-088388	Otolemur garnettii	57.32	8.00e-151	526.00
IUUC-Oar-089748	Ovis aries	58.02	7.00e-151	526.00
IUUC-Ptr-090616	Pan troglodytes	56.63	1.00e-147	516.00
IUUC-Pan-091769	Papio anubis	56.98	9.00e-102	363.00
IUUC-Psi-093334	Pelodiscus sinensis	57.38	1.00e-137	483.00
IUUC-Pfo-096801	Poecilia formosa	78.67	0.00e+00	744.00
IUUC-Pab-098139	Pongo abelii	56.04	7.00e-116	410.00
IUUC-Pca-100523	Procavia capensis	52.56	8.00e-94	337.00
IUUC-Pva-102286	Pteropus vampyrus	56.96	2.00e-142	499.00
IUUC-Rno-104831	Rattus norvegicus	56.88	2.00e-148	519.00
IUUC-Sha-107499	Sarcophilus harrisii	57.11	4.00e-149	521.00
IUUC-Sar-113389	Sorex araneus	57.11	1.00e-149	522.00
IUUC-Tgu-116769	Taeniopygia guttata	55.72	3.00e-144	504.00
IUUC-Tru-118774	Takifugu rubripes	78.03	0.00e+00	723.00
IUUC-Tsy-119595	Tarsius syrichta	48.28	1.00e-92	333.00
IUUC-Tni-119850	Tetraodon nigroviridis	80.04	0.00e+00	760.00
IUUC-Tbe-127938	Tupaia belangeri	51.30	1.00e-84	306.00
IUUC-Ttr-128193	Tursiops truncatus	56.94	1.00e-130	459.00
IUUC-Vpa-130275	Vicugna pacos	57.53	4.00e-150	524.00
IUUC-Xtr-131982	Xenopus tropicalis	51.06	9.00e-132	463.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence