iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053730

UUCD1 version

UUC-LoA-01090

Ensembl Protein ID

ENSLAFP00000013671.3

UniProt Accession

G3TGQ0; G3TGQ0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016286.3	ENSLAFT00000016285.3	ENSLAFP00000013671.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-88	296.6	212	559

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************667777776...5789***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  ++     ee e ++ ++ +  +++  ++++s i+dlF gqlks +kc++
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrappilannpapsppRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQA 386
           ********************9988777777776666655544555555555555555555***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilh...LkRfsfseeq 243
           c+ +s+++e f+dlslp+p++     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P++L+lh   L+Rf  s ++
   Q: 387  CGYRSTTFEVFCDLSLPIPKRGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHildLNRF--SASR 473
           *******************887441456**********************************************994445677..7777 PP
   S: 244  ksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaY 331
           +s +k +  v+fpl+ L+l  f +++      + +Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++v+e++v +   s++Y
   Q: 474  GSIKKSSVGVDFPLQrLSLGDFASDKAG----SPIYQLYALCNHSGSVHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVAS---SEGY 554
           999***********99*******99543....78*************************.777*******************...**** PP
   S: 332  vlfYk 336
           vlfY+
   Q: 555  VLFYQ 559
           ****8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPVNVQ PRVGSKLPLA PRARSKEHRN PAPGPNPMLR PLPPRPGPPE 60
ERLKKLELGQ GRTSGPRPRG PLRADHGVPL PGSPPSTVAV PLPSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAGG CCTCTGAGCA CCGCCTGGGC CGAACCCGAG AGCCACCTGT TAATGTCCAG 60
CCCCGGGTGG GATCCAAGCT ACCACTTGCC CCCCGGGCCC GCAGCAAGGA GCACCGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	95.07	0.00e+00	984.00
IUUC-Aca-004612	Anolis carolinensis	58.71	1.00e-172	599.00
IUUC-Ame-011548	Astyanax mexicanus	52.10	1.00e-102	366.00
IUUC-Bta-012626	Bos taurus	94.72	0.00e+00	951.00
IUUC-Cja-018853	Callithrix jacchus	94.54	0.00e+00	995.00
IUUC-Cfa-021167	Canis familiaris	95.60	0.00e+00	969.00
IUUC-Cpo-021305	Cavia porcellus	93.85	0.00e+00	924.00
IUUC-Csa-023454	Chlorocebus sabaeus	95.07	0.00e+00	1003.00
IUUC-Cho-024836	Choloepus hoffmanni	94.90	9.00e-107	380.00
IUUC-Dre-028454	Danio rerio	52.79	3.00e-106	378.00
IUUC-Dno-029955	Dasypus novemcinctus	90.89	0.00e+00	629.00
IUUC-Dor-031053	Dipodomys ordii	94.19	0.00e+00	1017.00
IUUC-Ete-032416	Echinops telfairi	95.19	5.00e-143	501.00
IUUC-Eca-033817	Equus caballus	95.07	0.00e+00	988.00
IUUC-Fca-036400	Felis catus	94.91	0.00e+00	961.00
IUUC-Gmo-038926	Gadus morhua	54.06	2.00e-103	369.00
IUUC-Gac-041331	Gasterosteus aculeatus	52.88	1.00e-105	376.00
IUUC-Ggo-045174	Gorilla gorilla	95.07	0.00e+00	1003.00
IUUC-Hsa-046443	Homo sapiens	94.89	0.00e+00	1003.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	94.05	0.00e+00	979.00
IUUC-Lch-050539	Latimeria chalumnae	61.06	1.00e-103	370.00
IUUC-Loc-051808	Lepisosteus oculatus	55.89	3.00e-115	408.00
IUUC-Mcc-055541	Macaca mulatta	95.07	0.00e+00	1003.00
IUUC-Meu-056279	Macropus eugenii	88.93	0.00e+00	942.00
IUUC-Mmr-060913	Microcebus murinus	95.25	0.00e+00	931.00
IUUC-Mdo-061807	Monodelphis domestica	88.75	0.00e+00	873.00
IUUC-Mmu-063599	Mus musculus	93.18	0.00e+00	941.00
IUUC-Mpu-066329	Mustela putorius furo	95.60	0.00e+00	967.00
IUUC-Mlu-067359	Myotis lucifugus	92.41	0.00e+00	868.00
IUUC-Nle-068975	Nomascus leucogenys	92.78	0.00e+00	970.00
IUUC-Opr-071096	Ochotona princeps	91.90	0.00e+00	928.00
IUUC-Ocu-074228	Oryctolagus cuniculus	94.57	0.00e+00	958.00
IUUC-Ola-086684	Oryzias latipes	50.28	4.00e-100	357.00
IUUC-Oga-088007	Otolemur garnettii	76.76	0.00e+00	749.00
IUUC-Oar-090226	Ovis aries	94.01	0.00e+00	741.00
IUUC-Ptr-091522	Pan troglodytes	95.07	0.00e+00	1003.00
IUUC-Pan-091954	Papio anubis	94.89	0.00e+00	997.00
IUUC-Psi-093216	Pelodiscus sinensis	59.56	0.00e+00	666.00
IUUC-Pfo-096257	Poecilia formosa	50.00	2.00e-100	359.00
IUUC-Pab-098691	Pongo abelii	95.25	0.00e+00	1004.00
IUUC-Pca-101133	Procavia capensis	88.91	0.00e+00	951.00
IUUC-Pva-102681	Pteropus vampyrus	92.78	0.00e+00	919.00
IUUC-Rno-105132	Rattus norvegicus	93.49	0.00e+00	965.00
IUUC-Sha-107145	Sarcophilus harrisii	88.33	0.00e+00	857.00
IUUC-Ssc-115586	Sus scrofa	96.13	0.00e+00	949.00
IUUC-Tgu-117491	Taeniopygia guttata	81.07	4.00e-114	403.00
IUUC-Tni-120746	Tetraodon nigroviridis	51.48	1.00e-94	339.00
IUUC-Tbe-127465	Tupaia belangeri	97.25	4.00e-125	441.00
IUUC-Ttr-128274	Tursiops truncatus	93.31	0.00e+00	938.00
IUUC-Xtr-131989	Xenopus tropicalis	48.53	8.00e-124	437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence