iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052222

Ensembl Protein ID

ENSLOCP00000002964.1

UniProt Accession

W5M3K6; W5M3K6_LEPOC

Genbank Protein ID

ENSLOCP00000002964

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01009465

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000002518.1	ENSLOCT00000002970.1	ENSLOCP00000002964.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.70e-15	56.9	58	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++v+++y+ye++++++L ++kG++++++  ++ d++W ++++ ++gk G +P+nFv+kl+
   Q: 58   DNLVIAIYSYEPNHSEDLGFEKGEKLKLL--NTDDQEWYMAQSLATGKTGYIPHNFVAKLD 116
           5799*************************..88999**********************996 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGCNCSSEYD DDWVENLDEY CEHCNCPLPP QSKNQYTDMR DGLIPYPSHT PPSSPLPDNL 60
VIAIYSYEPN HSEDLGFEKG EKLKLLNTDD QEWYMAQSLA TGKTGYIPHN FVAKLDTMET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAACATGGG CTGCAACTGC AGCTCGGAAT ATGACGACGA CTGGGTGGAA AACCTGGACG 60
AATACTGTGA GCACTGCAAC TGCCCGCTGC CTCCTCAGAG CAAAAACCAG GTAAGGGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001315	Ailuropoda melanoleuca	63.67	0.00e+00	684.00
IUUC-Ame-010831	Astyanax mexicanus	70.40	0.00e+00	629.00
IUUC-Bta-013264	Bos taurus	66.80	0.00e+00	697.00
IUUC-Cfa-021161	Canis familiaris	63.49	0.00e+00	683.00
IUUC-Cpo-022492	Cavia porcellus	67.96	0.00e+00	706.00
IUUC-Dre-028005	Danio rerio	71.99	0.00e+00	729.00
IUUC-Dno-029365	Dasypus novemcinctus	64.27	0.00e+00	655.00
IUUC-Eca-033325	Equus caballus	65.50	0.00e+00	667.00
IUUC-Fca-035908	Felis catus	67.18	0.00e+00	698.00
IUUC-Gmo-038984	Gadus morhua	67.38	0.00e+00	711.00
IUUC-Gga-040997	Gallus gallus	68.09	0.00e+00	726.00
IUUC-Gac-041854	Gasterosteus aculeatus	72.69	0.00e+00	767.00
IUUC-Ggo-045238	Gorilla gorilla	63.67	0.00e+00	687.00
IUUC-Hsa-047039	Homo sapiens	67.38	0.00e+00	702.00
IUUC-Itr-048479	Ictidomys tridecemlineatus	67.57	0.00e+00	702.00
IUUC-Lch-049568	Latimeria chalumnae	69.05	0.00e+00	741.00
IUUC-Meu-056879	Macropus eugenii	66.28	0.00e+00	686.00
IUUC-Mmr-060740	Microcebus murinus	67.38	0.00e+00	701.00
IUUC-Mdo-062192	Monodelphis domestica	67.96	0.00e+00	704.00
IUUC-Mmu-064241	Mus musculus	66.99	0.00e+00	700.00
IUUC-Mpu-066595	Mustela putorius furo	66.99	0.00e+00	697.00
IUUC-Mlu-067069	Myotis lucifugus	67.05	0.00e+00	697.00
IUUC-Opr-070472	Ochotona princeps	64.26	0.00e+00	684.00
IUUC-Ont-071711	Oreochromis niloticus	74.46	0.00e+00	758.00
IUUC-Ocu-074221	Oryctolagus cuniculus	66.67	0.00e+00	689.00
IUUC-Ola-087000	Oryzias latipes	70.67	0.00e+00	724.00
IUUC-Pan-091804	Papio anubis	67.18	0.00e+00	702.00
IUUC-Psi-093252	Pelodiscus sinensis	60.89	9.00e-176	609.00
IUUC-Pfo-096542	Poecilia formosa	71.84	0.00e+00	765.00
IUUC-Rno-105542	Rattus norvegicus	67.18	0.00e+00	700.00
IUUC-Sha-107524	Sarcophilus harrisii	67.96	0.00e+00	705.00
IUUC-Sar-113235	Sorex araneus	61.43	2.00e-163	568.00
IUUC-Tru-118559	Takifugu rubripes	69.63	0.00e+00	717.00
IUUC-Tni-119928	Tetraodon nigroviridis	67.63	0.00e+00	698.00
IUUC-Ttr-129002	Tursiops truncatus	60.37	0.00e+00	635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence