iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022412

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02020459

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003462.3	ENSCPOT00000003506.2	ENSCPOP00000003127.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.50e-10	40.9	30	96
E3 activity/RING/RING	5.40e-09	36.4	34	73

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawce 70
           + f C++ le+ ++Pv + +G+++ rs+I   l+s++ tcP +r+ l +e +    + rr+  ++++
   Q: 30   ASFDCAVCLEVLHQPVRTRCGHVFCRSCITTSLKSSKWTCPYCRAYLPSEGVPATDVARRMRAEYRN 96
           68**********************************************9999999999999999875 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+Cle + + p+ ++CgHvf+++C+   +      +s +++CP+Cr
   Q: 34   CAVCLEVLHQ-PVRTRCGHVFCRSCItTSL------KSSKWTCPYCR 73
           ********99.777***********95555......**********8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MGSLLSSDGG RGPPAPRAPE RSAEAPLPLA SFDCAVCLEV LHQPVRTRCG HVFCRSCITT 60
SLKSSKWTCP YCRAYLPSEG VPATDVARRM RAEYRNCAEC DTLVCLSEMR AHIRTCEKYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGTCCC TGCTGAGCAG CGACGGCGGC CGCGGGCCCC CCGCGCCGCG CGCCCCGGAG 60
CGCAGCGCCG AAGCCCCGCT GCCGCTCGCG TCCTTCGACT GCGCCGTGTG CTTGGAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	82.76	9.00e-115	405.00
IUUC-Aca-004839	Anolis carolinensis	58.99	3.00e-63	234.00
IUUC-Bta-012827	Bos taurus	79.65	5.00e-110	389.00
IUUC-Cja-018794	Callithrix jacchus	79.74	1.00e-110	391.00
IUUC-Cfa-021234	Canis familiaris	85.24	4.00e-108	383.00
IUUC-Csa-023406	Chlorocebus sabaeus	81.90	1.00e-113	401.00
IUUC-Cho-024427	Choloepus hoffmanni	69.49	1.00e-69	254.00
IUUC-Dno-030085	Dasypus novemcinctus	81.90	3.00e-113	400.00
IUUC-Dor-030911	Dipodomys ordii	61.64	6.00e-65	239.00
IUUC-Ete-032469	Echinops telfairi	76.29	8.00e-105	372.00
IUUC-Eca-034352	Equus caballus	81.90	5.00e-113	399.00
IUUC-Eeu-034889	Erinaceus europaeus	68.53	2.00e-89	321.00
IUUC-Fca-036116	Felis catus	85.51	9.00e-110	389.00
IUUC-Hsa-046518	Homo sapiens	81.90	3.00e-113	400.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	87.01	2.00e-92	331.00
IUUC-Laf-053363	Loxodonta africana	80.34	3.00e-111	393.00
IUUC-Meu-056101	Macropus eugenii	75.36	3.00e-92	330.00
IUUC-Mdo-062046	Monodelphis domestica	72.96	1.00e-97	348.00
IUUC-Mmu-063184	Mus musculus	79.29	2.00e-55	207.00
IUUC-Mpu-065708	Mustela putorius furo	81.90	4.00e-113	400.00
IUUC-Mlu-067561	Myotis lucifugus	83.62	3.00e-88	317.00
IUUC-Nle-069665	Nomascus leucogenys	80.37	3.00e-102	363.00
IUUC-Opr-070301	Ochotona princeps	69.83	2.00e-92	331.00
IUUC-Ocu-074562	Oryctolagus cuniculus	86.51	7.00e-63	231.00
IUUC-Oga-088958	Otolemur garnettii	81.90	2.00e-113	401.00
IUUC-Oar-089541	Ovis aries	85.23	4.00e-90	323.00
IUUC-Ptr-090989	Pan troglodytes	82.33	2.00e-114	404.00
IUUC-Pan-092372	Papio anubis	81.03	9.00e-113	399.00
IUUC-Pab-098718	Pongo abelii	71.12	4.00e-91	326.00
IUUC-Pca-100453	Procavia capensis	78.45	2.00e-108	384.00
IUUC-Pva-102931	Pteropus vampyrus	79.74	7.00e-109	385.00
IUUC-Rno-105771	Rattus norvegicus	79.15	6.00e-91	326.00
IUUC-Sha-107557	Sarcophilus harrisii	71.79	2.00e-100	358.00
IUUC-Sar-113435	Sorex araneus	84.92	3.00e-62	229.00
IUUC-Ssc-116388	Sus scrofa	81.47	9.00e-114	402.00
IUUC-Tsy-119439	Tarsius syrichta	84.18	3.00e-90	323.00
IUUC-Tbe-127417	Tupaia belangeri	54.46	6.00e-57	213.00
IUUC-Ttr-129212	Tursiops truncatus	80.60	1.00e-112	399.00
IUUC-Vpa-130153	Vicugna pacos	79.74	7.00e-111	392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence