iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073393

Ensembl Protein ID

ENSOANP00000006008.1

UniProt Accession

F6V085; F6V085_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000003791.3	ENSOANT00000006010.2	ENSOANP00000006008.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-09	38.3	532	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++   ++p+ e wiC+ Cr
   Q: 532  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LMNFPSGE-WICTFCR 576
           79*********....*******************.*******8.******8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

LHSFIHSIIE VNQNQKQVEQ DIKVAIFTLM VEINKKGKAL LHQLESLAKD HRMKLLQQQQ 60
EVAGLSKQLE HVMHFSKWAV SSSSSTALLY SKRLITYRLR YLLRARCDAS PATNTTIQFH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCATTCAT TCATTCATTC AGTAGTATTT ATTGAGCGCT TACTATGTGC AGAGCACTGT 60
ACTAAGCGCT TGGAATATAC AACTCGGCAA GAGATAGAGA CAATCCCTGC CCAATGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD

SMART

SM00502--BBC
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	81.32	0.00e+00	1026.00
IUUC-Apl-003697	Anas platyrhynchos	75.92	0.00e+00	897.00
IUUC-Bta-013282	Bos taurus	80.47	0.00e+00	1020.00
IUUC-Cja-018920	Callithrix jacchus	80.26	0.00e+00	1044.00
IUUC-Cfa-020984	Canis familiaris	81.45	0.00e+00	1035.00
IUUC-Cpo-022035	Cavia porcellus	80.66	0.00e+00	1046.00
IUUC-Csa-024208	Chlorocebus sabaeus	80.66	0.00e+00	1045.00
IUUC-Cho-024413	Choloepus hoffmanni	63.72	4.00e-110	392.00
IUUC-Dno-029145	Dasypus novemcinctus	81.18	0.00e+00	1068.00
IUUC-Dor-030396	Dipodomys ordii	80.66	0.00e+00	1039.00
IUUC-Dme-032143	Drosophila melanogaster	37.75	4.00e-34	139.00
IUUC-Ete-032414	Echinops telfairi	75.00	6.00e-133	468.00
IUUC-Eca-033489	Equus caballus	81.71	0.00e+00	1045.00
IUUC-Eeu-034654	Erinaceus europaeus	80.40	0.00e+00	637.00
IUUC-Fca-035844	Felis catus	77.82	0.00e+00	927.00
IUUC-Fal-036735	Ficedula albicollis	75.73	0.00e+00	953.00
IUUC-Gga-041124	Gallus gallus	74.61	0.00e+00	881.00
IUUC-Ggo-044542	Gorilla gorilla	80.79	0.00e+00	1047.00
IUUC-Hsa-046785	Homo sapiens	80.79	0.00e+00	1046.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	81.45	0.00e+00	1037.00
IUUC-Lch-050136	Latimeria chalumnae	64.47	6.00e-117	413.00
IUUC-Laf-054279	Loxodonta africana	79.37	0.00e+00	1027.00
IUUC-Mcc-055668	Macaca mulatta	80.79	0.00e+00	1046.00
IUUC-Meu-056195	Macropus eugenii	76.81	0.00e+00	753.00
IUUC-Mga-059272	Meleagris gallopavo	75.00	0.00e+00	886.00
IUUC-Mmr-060936	Microcebus murinus	79.74	0.00e+00	1028.00
IUUC-Mdo-062848	Monodelphis domestica	84.65	0.00e+00	1048.00
IUUC-Mmu-063598	Mus musculus	79.81	0.00e+00	1018.00
IUUC-Mpu-066272	Mustela putorius furo	81.05	0.00e+00	1023.00
IUUC-Mlu-067958	Myotis lucifugus	78.87	0.00e+00	1028.00
IUUC-Nle-069375	Nomascus leucogenys	80.79	0.00e+00	1046.00
IUUC-Opr-070836	Ochotona princeps	70.89	7.00e-162	563.00
IUUC-Ocu-074873	Oryctolagus cuniculus	79.29	0.00e+00	1014.00
IUUC-Oga-088692	Otolemur garnettii	79.87	0.00e+00	1008.00
IUUC-Oar-090160	Ovis aries	80.79	0.00e+00	1025.00
IUUC-Ptr-090756	Pan troglodytes	80.79	0.00e+00	1046.00
IUUC-Pan-091719	Papio anubis	80.53	0.00e+00	1041.00
IUUC-Psi-093433	Pelodiscus sinensis	77.29	0.00e+00	956.00
IUUC-Pab-098599	Pongo abelii	80.79	0.00e+00	1046.00
IUUC-Pca-100540	Procavia capensis	82.74	1.00e-149	523.00
IUUC-Pva-102478	Pteropus vampyrus	72.89	0.00e+00	852.00
IUUC-Rno-105478	Rattus norvegicus	64.93	1.00e-145	509.00
IUUC-Sha-106740	Sarcophilus harrisii	79.55	0.00e+00	963.00
IUUC-Sar-113615	Sorex araneus	80.66	0.00e+00	1031.00
IUUC-Ssc-115513	Sus scrofa	81.11	1.00e-120	424.00
IUUC-Tgu-117368	Taeniopygia guttata	77.20	0.00e+00	942.00
IUUC-Tsy-118904	Tarsius syrichta	80.79	0.00e+00	1054.00
IUUC-Tbe-127354	Tupaia belangeri	72.69	1.00e-174	606.00
IUUC-Ttr-128983	Tursiops truncatus	78.73	0.00e+00	922.00
IUUC-Vpa-130420	Vicugna pacos	79.34	0.00e+00	1003.00
IUUC-Vvi-131561	Vitis vinifera	47.17	2.00e-12	67.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence