iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048543

Ensembl Protein ID

ENSSTOP00000016302.1

UniProt Accession

I3MW07; I3MW07_ICTTR

Genbank Protein ID

ENSSTOP00000016302

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01009233

Gene Name

NOD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000025139.1	ENSSTOT00000028427.1	ENSSTOP00000016302.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	81.37	0.00e+00	1476.00	IUUC-Hsa-046093

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

CEMCSPEALQ AQRSHLVGLL VSGSLEGFES ILDWLLSWEV LSWEDYESLS LPGQPLSRLA 60
RRLLDTVGNK GAWGCEKLVA ALQEAQAGGQ SPEPRGGWDP HSLHPARDLQ SHRPAIVRRL 120

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Nucleotide Sequence
(Fasta)

GGGCTGGACT GTCCACATGA GAAGGCGGTA GCGGATGTCC CTCCCTGGGC ATCCCCGGGT 60
AAGAGGAGGG GCGCTGCCTG GGCTCGGCCT GGTCTTCACC GTCCTCTTCT CCTGGCTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS51450--LRR
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001822	Ailuropoda melanoleuca	79.23	0.00e+00	1343.00
IUUC-Ame-011021	Astyanax mexicanus	46.14	0.00e+00	847.00
IUUC-Bta-013241	Bos taurus	79.31	0.00e+00	1476.00
IUUC-Cja-019633	Callithrix jacchus	78.45	0.00e+00	1151.00
IUUC-Cfa-020039	Canis familiaris	79.72	0.00e+00	1462.00
IUUC-Cpo-022337	Cavia porcellus	78.87	0.00e+00	1431.00
IUUC-Csa-023906	Chlorocebus sabaeus	81.77	0.00e+00	1518.00
IUUC-Dre-027568	Danio rerio	46.64	0.00e+00	816.00
IUUC-Dno-029098	Dasypus novemcinctus	78.69	0.00e+00	1347.00
IUUC-Dor-031102	Dipodomys ordii	74.41	0.00e+00	671.00
IUUC-Ete-032943	Echinops telfairi	77.36	0.00e+00	1045.00
IUUC-Eca-034310	Equus caballus	82.18	0.00e+00	1468.00
IUUC-Eeu-034589	Erinaceus europaeus	79.04	2.00e-150	526.00
IUUC-Fca-036252	Felis catus	79.68	0.00e+00	756.00
IUUC-Gac-041442	Gasterosteus aculeatus	45.73	0.00e+00	782.00
IUUC-Ggo-044861	Gorilla gorilla	81.67	0.00e+00	1471.00
IUUC-Hsa-046093	Homo sapiens	81.47	0.00e+00	1466.00
IUUC-Lch-049454	Latimeria chalumnae	52.31	0.00e+00	872.00
IUUC-Laf-053553	Loxodonta africana	80.46	0.00e+00	1356.00
IUUC-Mcc-055772	Macaca mulatta	81.47	0.00e+00	1501.00
IUUC-Meu-056785	Macropus eugenii	67.97	6.00e-114	405.00
IUUC-Mmr-060596	Microcebus murinus	82.18	0.00e+00	1494.00
IUUC-Mdo-062983	Monodelphis domestica	66.35	0.00e+00	1041.00
IUUC-Mmu-063951	Mus musculus	75.72	0.00e+00	1417.00
IUUC-Mpu-066412	Mustela putorius furo	78.91	0.00e+00	1444.00
IUUC-Mlu-067601	Myotis lucifugus	77.98	0.00e+00	1330.00
IUUC-Nle-069913	Nomascus leucogenys	81.45	0.00e+00	1229.00
IUUC-Opr-070999	Ochotona princeps	79.78	0.00e+00	890.00
IUUC-Ont-072512	Oreochromis niloticus	46.14	0.00e+00	833.00
IUUC-Oan-073564	Ornithorhynchus anatinus	61.16	0.00e+00	1040.00
IUUC-Ocu-074837	Oryctolagus cuniculus	82.58	0.00e+00	1503.00
IUUC-Ola-086555	Oryzias latipes	44.97	0.00e+00	782.00
IUUC-Oga-088909	Otolemur garnettii	80.56	0.00e+00	1434.00
IUUC-Oar-089315	Ovis aries	78.61	0.00e+00	1417.00
IUUC-Ptr-090542	Pan troglodytes	81.67	0.00e+00	1473.00
IUUC-Pan-092545	Papio anubis	81.67	0.00e+00	1502.00
IUUC-Pma-094167	Petromyzon marinus	34.80	2.00e-65	243.00
IUUC-Pfo-096976	Poecilia formosa	45.15	0.00e+00	802.00
IUUC-Pab-098481	Pongo abelii	81.35	0.00e+00	1459.00
IUUC-Pca-100135	Procavia capensis	73.76	0.00e+00	1228.00
IUUC-Pva-102127	Pteropus vampyrus	77.14	0.00e+00	1298.00
IUUC-Rno-105783	Rattus norvegicus	78.81	0.00e+00	1452.00
IUUC-Sar-113448	Sorex araneus	73.05	0.00e+00	874.00
IUUC-Tru-118708	Takifugu rubripes	45.05	0.00e+00	749.00
IUUC-Tni-120172	Tetraodon nigroviridis	36.42	7.00e-33	134.00
IUUC-Tbe-127661	Tupaia belangeri	83.23	0.00e+00	759.00
IUUC-Ttr-128318	Tursiops truncatus	73.92	0.00e+00	1264.00
IUUC-Vpa-130502	Vicugna pacos	71.05	6.00e-150	524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence