iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Sce-106405

UUCD1 version

UUC-SaC-00044

Ensembl Protein ID

YDR460W

UniProt Accession

Q03290; D6VT84; P89104; TFB3_YEAST

Genbank Protein ID

AAB40629.1; AAB64899.1; DAA12294.1

Protein Name

RNA polymerase II transcription factor B subunit 3; RNA polymerase II transcription factor B 38 kDa subunit; RNA polymerase II transcription factor B p38 subunit

Genbank Nucleotide ID

U62805; U33050; BK006938

Gene Name

TFB3; RIG2; YDR460W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YDR460W	YDR460W	YDR460W

Annotation

mRNA Expression
GEO	FFGED
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15837426

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	0.00099	18.1	13	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.....kdgplvlp.CgHvfhadClqkwpglknssskefrCPl 44
           C+iC++d       +  lv+p C H ++++C+ ++     +s + ++CP+
   Q: 13   CPICKTDRylspdVK-FLVNPeCYHRICESCVDRI-----FSLGPAQCPY 56
           ****99776775333.556779**********999.....8999999**7 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.

Protein Sequence
(Fasta)

MLMDEYEENK DMCPICKTDR YLSPDVKFLV NPECYHRICE SCVDRIFSLG PAQCPYKGCD 60
KILRKNKFKT QIFDDVEVEK EVDIRKRVFN VFNKTIDDFN GDLVEYNKYL EEVEDIIYKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTATGG ATGAGTATGA GGAAAACAAG GACATGTGTC CGATCTGTAA GACAGATCGA 60
TACCTTTCTC CGGATGTGAA ATTTTTGGTG AATCCTGAAT GCTATCACAG GATCTGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015877--Cdk-activating_kinase_MAT1_cen
IPR004575--MAT1/Tfb3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF06391--MAT1
PF17121--zf-C3HC4_5

Gene Ontology

GO:0005675--C:holo TFIIH complex
GO:0070985--C:TFIIK complex
GO:0061575--F:cyclin-dependent protein serine/threonine kinase activator activity
GO:0008270--F:zinc ion binding
GO:0007049--P:cell cycle
GO:0006289--P:nucleotide-excision repair
GO:0070816--P:phosphorylation of RNA polymerase II C-terminal domain
GO:0000079--P:regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

sce:YDR460W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000821	Aegilops tauschii	34.29	1.00e-03	34.70
IUUC-Aml-002414	Ailuropoda melanoleuca	28.66	9.00e-30	121.00
IUUC-Atr-002627	Amborella trichopoda	51.47	4.00e-14	68.90
IUUC-Apl-003312	Anas platyrhynchos	44.04	2.00e-22	97.10
IUUC-Aca-004731	Anolis carolinensis	38.10	6.00e-31	125.00
IUUC-Aly-006244	Arabidopsis lyrata	37.18	6.00e-10	55.10
IUUC-Ath-007136	Arabidopsis thaliana	35.90	2.00e-09	53.10
IUUC-Ago-007788	Ashbya gossypii	71.96	4.00e-136	475.00
IUUC-Acl-008179	Aspergillus clavatus	36.69	8.00e-57	212.00
IUUC-Afl-008465	Aspergillus flavus	38.42	3.00e-58	216.00
IUUC-Afu-009056	Aspergillus fumigatus	36.20	2.00e-49	187.00
IUUC-Ani-009235	Aspergillus nidulans	27.95	6.00e-15	72.40
IUUC-Ang-009677	Aspergillus niger	35.76	1.00e-53	201.00
IUUC-Aor-010017	Aspergillus oryzae	38.42	3.00e-58	216.00
IUUC-Ate-010259	Aspergillus terreus	34.83	2.00e-50	190.00
IUUC-Ame-010934	Astyanax mexicanus	39.26	3.00e-23	100.00
IUUC-Bgr-012074	Blumeria graminis	34.29	1.00e-48	184.00
IUUC-Bta-013329	Bos taurus	29.30	9.00e-30	121.00
IUUC-Bci-013704	Botrytis cinerea	35.47	3.00e-51	193.00
IUUC-Bdi-014606	Brachypodium distachyon	46.15	6.00e-11	58.50
IUUC-Bol-015807	Brassica oleracea	35.90	6.00e-06	42.40
IUUC-Bra-017894	Brassica rapa	43.66	1.00e-11	60.80
IUUC-Cel-018428	Caenorhabditis elegans	32.08	2.00e-20	90.50
IUUC-Cja-019720	Callithrix jacchus	45.19	1.00e-29	121.00
IUUC-Cfa-020319	Canis familiaris	28.98	5.00e-30	122.00
IUUC-Cpo-021652	Cavia porcellus	45.19	4.00e-30	122.00
IUUC-Cre-022749	Chlamydomonas reinhardtii	38.57	5.00e-12	62.00
IUUC-Csa-023560	Chlorocebus sabaeus	29.52	4.00e-30	123.00
IUUC-Cho-024696	Choloepus hoffmanni	35.53	3.00e-04	38.50
IUUC-Cin-025502	Ciona intestinalis	28.48	7.00e-32	129.00
IUUC-Csv-026302	Ciona savignyi	29.90	4.00e-33	132.00
IUUC-Cgl-026541	Colletotrichum gloeosporioides	52.63	3.00e-10	56.60
IUUC-Cne-027055	Cryptococcus neoformans	44.30	3.00e-36	143.00
IUUC-Cme-027128	Cyanidioschyzon merolae	50.00	2.00e-09	53.90
IUUC-Dre-027714	Danio rerio	45.93	3.00e-30	123.00
IUUC-Dno-029232	Dasypus novemcinctus	45.19	3.00e-29	119.00
IUUC-Dor-030996	Dipodomys ordii	48.72	2.00e-13	67.40
IUUC-Dse-031359	Dothistroma septosporum	39.32	1.00e-49	187.00
IUUC-Dme-031992	Drosophila melanogaster	46.38	7.00e-31	125.00
IUUC-Ete-032973	Echinops telfairi	41.07	1.00e-06	45.10
IUUC-Eca-034116	Equus caballus	45.19	1.00e-29	121.00
IUUC-Eeu-035143	Erinaceus europaeus	34.07	9.00e-17	78.60
IUUC-Fca-035960	Felis catus	45.19	9.00e-30	121.00
IUUC-Fal-037039	Ficedula albicollis	43.12	2.00e-21	93.60
IUUC-Fox-037882	Fusarium oxysporum	36.51	8.00e-41	159.00
IUUC-Fso-038318	Fusarium solani	35.49	1.00e-46	178.00
IUUC-Gmo-038905	Gadus morhua	41.48	2.00e-26	110.00
IUUC-Ggr-039857	Gaeumannomyces graminis	44.44	7.00e-22	95.90
IUUC-Gga-041216	Gallus gallus	45.19	4.00e-30	123.00
IUUC-Gac-041987	Gasterosteus aculeatus	43.70	4.00e-27	112.00
IUUC-Gma-044312	Glycine max	51.47	1.00e-13	67.40
IUUC-Ggo-044930	Gorilla gorilla	25.40	5.00e-19	85.90
IUUC-Hsa-045876	Homo sapiens	29.52	4.00e-30	123.00
IUUC-Hvu-047088	Hordeum vulgare	43.08	7.00e-10	54.70
IUUC-Itr-048476	Ictidomys tridecemlineatus	44.74	2.00e-24	103.00
IUUC-Kpa-049202	Komagataella pastoris	42.63	2.00e-62	230.00
IUUC-Lch-049886	Latimeria chalumnae	42.96	3.00e-27	113.00
IUUC-Lpe-050952	Leersia perrieri	45.21	2.00e-11	59.70
IUUC-Loc-052556	Lepisosteus oculatus	45.19	2.00e-28	117.00
IUUC-Lma-053002	Leptosphaeria maculans	54.86	6.00e-44	169.00
IUUC-Laf-054516	Loxodonta africana	45.19	5.00e-30	122.00
IUUC-Mcc-054761	Macaca mulatta	45.19	1.00e-29	121.00
IUUC-Mor-057048	Magnaporthe oryzae	46.32	3.00e-31	127.00
IUUC-Mpo-057598	Magnaporthe poae	45.30	4.00e-20	88.60
IUUC-Mtr-058131	Medicago truncatula	52.94	6.00e-14	68.20
IUUC-Mla-059009	Melampsora laricipopulina	53.47	1.00e-39	153.00
IUUC-Mga-060199	Meleagris gallopavo	44.95	1.00e-22	97.40
IUUC-Mvi-060382	Microbotryum violaceum	33.54	1.00e-39	155.00
IUUC-Mmr-061671	Microcebus murinus	45.19	2.00e-29	120.00
IUUC-Mdo-062228	Monodelphis domestica	28.98	9.00e-29	118.00
IUUC-Mmu-064416	Mus musculus	45.19	6.00e-30	122.00
IUUC-Mac-064807	Musa acuminata	52.24	6.00e-13	65.10
IUUC-Mpu-066455	Mustela putorius furo	45.19	9.00e-30	121.00
IUUC-Mlu-067325	Myotis lucifugus	44.74	8.00e-24	101.00
IUUC-Nfi-068566	Neosartorya fischeri	37.17	2.00e-51	194.00
IUUC-Ncr-068687	Neurospora crassa	28.91	2.00e-39	154.00
IUUC-Nle-069937	Nomascus leucogenys	29.52	4.00e-30	123.00
IUUC-Opr-070321	Ochotona princeps	45.35	4.00e-18	83.20
IUUC-Ont-072636	Oreochromis niloticus	44.44	2.00e-28	117.00
IUUC-Oan-072915	Ornithorhynchus anatinus	40.37	9.00e-19	84.70
IUUC-Ocu-074547	Oryctolagus cuniculus	47.01	3.00e-26	110.00
IUUC-Oba-075318	Oryza barthii	47.69	6.00e-11	58.50
IUUC-Obr-076081	Oryza brachyantha	46.15	3.00e-11	59.70
IUUC-Ogl-077072	Oryza glaberrima	47.69	6.00e-11	58.50
IUUC-Ogu-078667	Oryza glumaepatula	46.15	1.00e-10	57.80
IUUC-Oin-079796	Oryza indica	47.69	3.00e-11	59.30
IUUC-Olo-080344	Oryza longistaminata	47.17	3.00e-07	46.20
IUUC-Ome-081805	Oryza meridionalis	47.69	5.00e-11	59.30
IUUC-Oni-082783	Oryza nivara	47.69	6.00e-11	58.50
IUUC-Opu-083247	Oryza punctata	44.62	2.00e-10	57.00
IUUC-Oru-084336	Oryza rufipogon	47.69	6.00e-11	58.50
IUUC-Osa-086047	Oryza sativa	47.69	3.00e-11	59.30
IUUC-Ola-086780	Oryzias latipes	44.44	2.00e-28	117.00
IUUC-Olu-087653	Ostreococcus lucimarinus	35.71	7.00e-08	47.80
IUUC-Oga-088012	Otolemur garnettii	45.19	4.00e-29	119.00
IUUC-Oar-090274	Ovis aries	25.48	3.00e-20	90.10
IUUC-Ptr-090780	Pan troglodytes	29.52	4.00e-30	123.00
IUUC-Pan-091815	Papio anubis	40.16	2.00e-19	87.00
IUUC-Psi-093883	Pelodiscus sinensis	44.44	2.00e-30	124.00
IUUC-Pma-094717	Petromyzon marinus	42.42	3.00e-10	56.60
IUUC-Pno-094958	Phaeosphaeria nodorum	35.22	8.00e-45	172.00
IUUC-Ppa-095445	Physcomitrella patens	57.81	5.00e-15	72.00
IUUC-Pfo-096051	Poecilia formosa	44.44	1.00e-28	118.00
IUUC-Pab-097609	Pongo abelii	45.19	3.00e-29	120.00
IUUC-Pop-099332	Populus trichocarpa	50.00	5.00e-14	67.40
IUUC-Pca-101094	Procavia capensis	45.87	2.00e-22	97.40
IUUC-Ppe-101481	Prunus persica	50.00	2.00e-12	63.20
IUUC-Pva-103219	Pteropus vampyrus	45.19	2.00e-29	120.00
IUUC-Pgr-103557	Puccinia graminis	54.35	2.00e-40	157.00
IUUC-Ptt-103719	Puccinia triticina	54.35	4.00e-40	156.00
IUUC-Pte-104301	Pyrenophora teres	45.32	2.00e-33	133.00
IUUC-Pyt-104486	Pyrenophora triticirepentis	47.29	1.00e-32	131.00
IUUC-Rno-105846	Rattus norvegicus	45.19	8.00e-30	122.00
IUUC-Sha-107594	Sarcophilus harrisii	44.04	9.00e-21	90.90
IUUC-Sja-107951	Schizosaccharomyces japonicus	38.08	1.00e-50	191.00
IUUC-Spo-108137	Schizosaccharomyces pombe	37.17	2.00e-47	181.00
IUUC-Ssl-108503	Sclerotinia sclerotiorum	35.78	4.00e-57	213.00
IUUC-Smo-108895	Selaginella moellendorffii	33.58	4.00e-15	72.00
IUUC-Sit-110672	Setaria italica	41.10	3.00e-10	56.20
IUUC-Sly-111744	Solanum lycopersicum	50.00	3.00e-12	62.80
IUUC-Stu-112343	Solanum tuberosum	50.00	3.00e-12	62.80
IUUC-Sar-113298	Sorex araneus	45.93	4.00e-30	122.00
IUUC-Sbi-113918	Sorghum bicolor	46.15	1.00e-10	57.80
IUUC-Sre-114991	Sporisorium reilianum	49.34	1.00e-34	138.00
IUUC-Ssc-116152	Sus scrofa	44.95	3.00e-22	96.30
IUUC-Tgu-116452	Taeniopygia guttata	43.70	1.00e-28	118.00
IUUC-Tru-118621	Takifugu rubripes	29.21	7.00e-28	115.00
IUUC-Tsy-119500	Tarsius syrichta	44.44	6.00e-29	119.00
IUUC-Tni-120454	Tetraodon nigroviridis	39.64	9.00e-17	78.60
IUUC-Tca-121192	Theobroma cacao	50.70	1.00e-13	67.00
IUUC-Tre-122011	Trichoderma reesei	35.02	1.00e-43	167.00
IUUC-Tvi-122317	Trichoderma virens	36.88	3.00e-49	186.00
IUUC-Tae-123854	Triticum aestivum	43.08	3.00e-10	56.20
IUUC-Tur-126556	Triticum urartu	43.08	4.00e-10	55.80
IUUC-Tme-127135	Tuber melanosporum	40.07	5.00e-41	159.00
IUUC-Tbe-127287	Tupaia belangeri	44.04	5.00e-19	85.90
IUUC-Ttr-128864	Tursiops truncatus	45.19	1.00e-29	121.00
IUUC-Uma-129539	Ustilago maydis	50.75	2.00e-35	140.00
IUUC-Vda-129713	Verticillium dahliae	32.74	4.00e-36	143.00
IUUC-Vpa-130462	Vicugna pacos	44.04	1.00e-21	95.10
IUUC-Vvi-130988	Vitis vinifera	51.47	8.00e-13	64.70
IUUC-Xtr-131830	Xenopus tropicalis	36.51	2.00e-28	116.00
IUUC-Xma-133952	Xiphophorus maculatus	45.19	6.00e-29	119.00
IUUC-Yli-134433	Yarrowia lipolytica	42.90	1.00e-65	241.00
IUUC-Zma-134867	Zea mays	44.62	2.00e-10	56.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence