iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036420

Ensembl Protein ID

ENSFCAP00000011715.2

UniProt Accession

M3WHA5; M3WHA5_FELCA

Genbank Protein ID

ENSFCAP00000011715

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02164687

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000012631.3	ENSFCAT00000012634.3	ENSFCAP00000011715.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-13	50.8	367	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 367  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 421
           689********************9999.999********7.99************86 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MAPEEDAGGE ALEGSFWEAG NYRRTVQRVE DGHRLCGDLI SCFQERARIE KAYAQQLADW 60
ARKWRGTVEK GPQYGTLEKA WHAFFTAAER LSALHLEVRE KLQGQDSERV RSWQRGAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGAGAGCGG CAGGACTCTG GCCGGAGCGT GGCCGGACCC CCACCCTCCG AGACGCCCAG 60
GGAGGACGCG GTGAGTGCTG CCCCGGCGGG AACCACGGGG AGGCGGCGGC GGGAGAGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

fca:101091971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	97.00	0.00e+00	660.00
IUUC-Apl-003211	Anas platyrhynchos	65.94	0.00e+00	629.00
IUUC-Aca-004256	Anolis carolinensis	65.05	1.00e-179	622.00
IUUC-Ame-011049	Astyanax mexicanus	60.59	2.00e-155	542.00
IUUC-Bta-013322	Bos taurus	92.12	0.00e+00	778.00
IUUC-Cja-018907	Callithrix jacchus	95.05	0.00e+00	801.00
IUUC-Cfa-021126	Canis familiaris	96.93	0.00e+00	808.00
IUUC-Cpo-021491	Cavia porcellus	92.22	0.00e+00	785.00
IUUC-Csa-023107	Chlorocebus sabaeus	96.46	0.00e+00	808.00
IUUC-Dre-027933	Danio rerio	60.18	8.00e-149	520.00
IUUC-Dno-029002	Dasypus novemcinctus	94.81	0.00e+00	766.00
IUUC-Eca-033824	Equus caballus	96.23	0.00e+00	811.00
IUUC-Eeu-035122	Erinaceus europaeus	85.55	6.00e-174	602.00
IUUC-Fal-037277	Ficedula albicollis	65.65	0.00e+00	631.00
IUUC-Gga-040941	Gallus gallus	66.30	0.00e+00	633.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.27	8.00e-143	499.00
IUUC-Ggo-045211	Gorilla gorilla	95.99	0.00e+00	804.00
IUUC-Hsa-046053	Homo sapiens	96.46	0.00e+00	808.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	94.10	0.00e+00	794.00
IUUC-Loc-052808	Lepisosteus oculatus	62.41	2.00e-159	555.00
IUUC-Laf-054211	Loxodonta africana	93.87	0.00e+00	764.00
IUUC-Mcc-055044	Macaca mulatta	96.46	0.00e+00	808.00
IUUC-Mga-059216	Meleagris gallopavo	66.45	0.00e+00	635.00
IUUC-Mmr-061172	Microcebus murinus	96.23	0.00e+00	812.00
IUUC-Mdo-062600	Monodelphis domestica	87.26	0.00e+00	777.00
IUUC-Mmu-063218	Mus musculus	92.69	0.00e+00	786.00
IUUC-Mpu-066819	Mustela putorius furo	96.70	0.00e+00	662.00
IUUC-Mlu-067597	Myotis lucifugus	92.34	0.00e+00	806.00
IUUC-Nle-069195	Nomascus leucogenys	95.99	0.00e+00	804.00
IUUC-Opr-071050	Ochotona princeps	94.35	0.00e+00	790.00
IUUC-Ont-071612	Oreochromis niloticus	56.49	6.00e-143	500.00
IUUC-Oan-073256	Ornithorhynchus anatinus	87.09	0.00e+00	735.00
IUUC-Ocu-074653	Oryctolagus cuniculus	95.75	0.00e+00	773.00
IUUC-Oga-089040	Otolemur garnettii	94.34	0.00e+00	802.00
IUUC-Oar-089918	Ovis aries	95.85	0.00e+00	787.00
IUUC-Ptr-091307	Pan troglodytes	96.46	0.00e+00	808.00
IUUC-Pan-092512	Papio anubis	96.46	0.00e+00	808.00
IUUC-Pfo-096881	Poecilia formosa	60.90	7.00e-156	543.00
IUUC-Pab-098620	Pongo abelii	96.46	0.00e+00	808.00
IUUC-Pva-102464	Pteropus vampyrus	93.40	0.00e+00	783.00
IUUC-Rno-106091	Rattus norvegicus	92.69	0.00e+00	784.00
IUUC-Sha-107474	Sarcophilus harrisii	88.44	0.00e+00	778.00
IUUC-Ssc-116128	Sus scrofa	96.23	0.00e+00	812.00
IUUC-Tgu-117511	Taeniopygia guttata	63.16	2.00e-178	618.00
IUUC-Tru-118005	Takifugu rubripes	60.41	3.00e-141	494.00
IUUC-Tni-119851	Tetraodon nigroviridis	65.22	3.00e-143	501.00
IUUC-Ttr-129313	Tursiops truncatus	96.70	0.00e+00	841.00
IUUC-Vpa-130760	Vicugna pacos	97.27	4.00e-102	364.00
IUUC-Xtr-132697	Xenopus tropicalis	56.94	8.00e-139	486.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence